About James Meigs, MD

James B. Meigs MD, MPH is Professor of Medicine at Harvard Medical School, Physician, Division of General Internal Medicine, Massachusetts General Hospital and Co-Director of the MGH Clinical Research Program’s Clinical Effectiveness Research Group.

For over 25 years Dr. Meigs has been a practicing primary care general internist in the MGH Internal Medicine Associates.

Dr. Meigs' research interest for over 20 years has been the cause and prevention of type 2 diabetes and cardiovascular disease. He has authored more than 400 peer-reviewed scientific papers (Thomson Reuters Highly Cited Researcher 2014), supported by multiple NIH and foundation research grants, currently including 2R01 DK078616: Common Genetic Variation and Diabetes Quantitative Traits (PI), U01 DK085526: Multiethnic Study of Type 2 Diabetes Genetics (Co-PI) and K24 DK080140: Epidemiology of Precursors to Type 2 Diabetes (PI). He is a senior scientific leader of several large international type 2 diabetes-related genetic consortia, including MAGIC (Meta Analysis of Glucose and Insulin Consortium), AAGILE (African American Glucose and Insulin genetic Epidemiology) and CHARGE (Cohorts for Heart and Aging Genetic Epidemiology).

Dr. Meigs has mentored over 50 junior clinical research investigators, supported in part by the NIDDK K24 award. In 2009, he was awarded the American Diabetes Association’s Kelly West Award for Outstanding Achievement in Diabetes Epidemiology.

Departments, Centers, & Programs:

Clinical Interests:

Treats:

Locations

Internal Medicine Associates Team 3
15 Parkman Street
Boston, MA 02114-3117
617-724-2700
Fax: 617-726-6861

Medical Education

  • MD, Harvard Medical School
  • Residency, Massachusetts General Hospital
  • Fellowship, Massachusetts General Hospital

American Board Certifications

  • Internal Medicine, American Board of Internal Medicine

Accepted Insurance Plans

Note: This provider may accept more insurance plans than shown; please call the practice to find out if your plan is accepted.


Research

Dr. Meigs' research interest for more than 20 years has been the cause and prevention of type 2 diabetes and cardiovascular disease using molecular and genetic epidemiology and translational health services research approaches. He has authored more than 400 peer-reviewed scientific papers, supported by multiple National Institutes of Health and foundation research grants.

Publications

  • Selected publications:

    1. Berkowitz SA, Meigs JB, Wexler DJ. Age at type 2 diabetes onset and glycaemic control: results from the National Health and Nutrition Examination Survey (NHANES) 2005-2010. Diabetologia. 2013 Sep 1. [Epub ahead of print] PMID: 23995472
    2. DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium. Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nat Genet. 2014 Mar;46(3):234-44. PMID: 24509480
    3. Vassy JL, Hivert MF, Porneala B, Dauriz M, Florez JC, Dupuis J, Siscovick DS, Fornage M, Rasmussen-Torvik LJ, Bouchard C, Meigs JB. Polygenic type 2 diabetes prediction at the limit of common variant detection. Diabetes. 2014 Feb 11. [Epub ahead of print] PMID: 24520119
    4. Cornes BK, Brody JA, Nikpoor N, Morrison AC, Dang HCP, Ahn BS, Wang S, Dauriz M, Barzilay JI, Dupuis J, Florez JC, Coresh J, Gibbs RA, Kao WHL, Liu C-T, McKnight B, MuznyD, Pankow JS, Reid JG, White CC, Johnson AD, Wong TY, Psaty BM, Boerwinkle E, Rotter JI, Siscovick DS, Sladek R, Meigs JB. Association of Levels of Fasting Glucose and Insulin with Rare Variants at the Chromosome 11p11.2-MADD Locus: the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Targeted Sequencing Study. Circulation Cardiovascular Genetics 2014, in press.
    5. Meigs JB, Grant RW, Piccolo R, Lopez L, Florez JC, Porneala B, Marceau L, McKinlay JB. Association of African Genetic Ancestry with Fasting Glucose and Hemoglobin A1c Levels in Non-Diabetic Individuals: The Boston Area Community Health (BACH) Prediabetes Study. Diabetologia 2014; in press.