Departments, Centers, & Programs:
Massachusetts General Hospital
55 Fruit Street
Boston, MA 02114-2696
- MBBS, Kings College @ University of Durham
- MD, Newcastle University
- Residency, Boston Children's Hospital
- Fellowship, Children's Cancer Research Foundation
American Board Certifications
- Anatomic Pathology, American Board of Pathology
- Neuropathology, American Board of Pathology
Accepted Insurance Plans
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Dr. Hedley-Whyte is co-investigator of the Neuropathology Core of the Massachusetts Alzheimer's Disease Research Center (ADRC). The Core's mission is to conduct neuropathological examinations on brains submitted to the Harvard Brain Tissue Resource Center and distribute tissue to ADRC investigators. The ADRC includes investigators with expertise in neuropathology, morphometry, immunocytochemistry, microarray technology, gene chip applications, laser capture techniques and in situ hybridization, and brain banking procedures. With Dr. Matthew Frosch, we use procedures to enhance the value of the brain tissues to investigators whose specific research projects depend upon receiving carefully prepared and diagnosed tissue. Standardized protocols for tissue acquisition, and dissection procedures ensure complete and reproducible examinations across all cases. The Tissue Resource Center maintains a rich collection of paraffin blocks with frozen, and formalin-fixed tissue. Frozen tissue is available as small blocks, and thin whole coronal brain slices, in which all anatomical structures are clearly visible. Separate databases within the Harvard Brain Tissue Resource Center contain information on tissue availability, location, and investigator allocation.
Dr. Hedley-Whyte's other research interests include predictive histological markers of pituitary tumor behavior.
- Pathologic and clinical features of pituitary adenomas showing TSH immunoreactivity. Tritos NA, Eppakayala S, Swearingen B, Hedley-Whyte ET, Miller KK, Nachtigall LB, Grinspoon SK, Biller BM, Klibanski A. Pituitary. 2013 Sep; 16(3):287-93.
- Ataxia, dementia, and hypogonadotropism caused by disordered ubiquitination.Margolin DH, Kousi M, Chan YM, Lim ET, Schmahmann JD, Hadjivassiliou M, Hall JE, Adam I, Dwyer A, Plummer L, Aldrin SV, O'Rourke J, Kirby A, Lage K, Milunsky A, Milunsky JM, Chan J, Hedley-Whyte ET, Daly MJ, Katsanis N, Seminara SB. N Engl J Med. 2013 May 23; 368(21):1992-2003
- Bifocal intracranial tumors of nongerminomatous germ cell etiology: diagnostic and therapeutic implications. Aizer AA, Sethi RV, Hedley-Whyte ET, Ebb D, Tarbell NJ, Yock TI, Macdonald SM. Neuro Oncol. 2013 Jul; 15(7):955-60.