Departments, Centers, & Programs:
Spaulding Rehabilitation Hospital
300 First Avenue
Charlestown, MA 02129-3109
- PhD, Hofstra University
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For the last two decades, my clinical and research activities have centered on assessment and treatment interventions designed for persons with severe acquired brain injury (ABI). My work in assessment has focused on developing neurobehavioral and functional neuroimaging methodologies to characterize the pathophysiologic, neurocognitive, neurobehavioral and functional sequelae of severe ABI. Over the last 10 years, I have been involved in development projects and multicenter clinical trials concerning novel neuromodulatory interventions aimed at promoting functional improvement during the subacute and chronic phases of recovery from brain injury. I served as Project Director on a recently-completed 11-site randomized controlled trial testing the effectiveness of a medication intended to improve functional outcome in patients recovering from severe traumatic brain injury and Co-PI on a three-center pilot trial of thalamic deep brain stimulation for treatment of post-traumatic minimally conscious state. I am currently chairing a joint initiative between the American Academy of Neurology, American Congress of Rehabilitation Medicine and the National Institute on Disability and Rehabilitation Research Traumatic Brain Injury Model Systems to update existing assessment and treatment guidelines for management of patients with disorders of consciousness.
GiacinoJT, Ashwal S, Childs N,et al. The minimally conscious state: Definition and diagnostic criteria Neurology 2002;58:349-53.
GiacinoJT, Kalmar K, Whyte J. The JFK coma recovery scale-revised: Measurement characteristics and diagnostic utility. Arch Phys Med Rehabil 2004;85:2020-9.
SchiffND, Rodriguez-Moreno D, Kamal A, Kim KHS, Giacino J, Plum F, Hirsch J. Functional MRI reveals largescale network activation in minimally conscious patients. Neurology 2005;64:514-23.
VossHU, Ulug AM, Dyke JP, Watts R, Kobylarz EJ, McCandliss B, Heier LA, Beattie BJ,Hamacher KA, Vallabhajosula S, Goldsmith SJ, Ballon D, Giacino JT, Schiff ND. Axonalre-growth in late recovery from the minimally conscious state. J Clin Invest2006;116:205-11.
Schiff ND, GiacinoJT (co-lead author),Kalmar K, et al.Behavioral improvements with thalamic stimulation after severe traumatic braininjury. Nature 2007;448:600-4.
Rodriguez-MorenoD, Schiff ND, Giacino JT, et al. A network approach to assess cognition in disorders of consciousness.Neurology 2010;75:1871-78.