Departments, Centers, & Programs:
55 Fruit Street
Boston, MA 02114-2696
MGH Waltham Allergy
52 Second Avenue
Waltham, MA 02451-1132
- MD, University of Maryland School of Medicine
- Residency, University of Chicago Medical Center
- Fellowship, Massachusetts General Hospital
American Board Certifications
- Allergy & Immunology, American Board of Allergy and Immunology
Accepted Insurance Plans
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My current research is focused on two main areas of interest: 1) the role of chemokines in allergic diseases and 2) allergen-specific T cell immune responses in human asthma. Our lab has identified CCR8 as a human CCL18 receptor, which may have important implications for understanding the pathogenesis of allergic/eosinophilic diseases. I plan to develop novel reporter mouse models to investigate the role of this CCR8 and its chemokine ligands in allergic diseases, including asthma and atopic dermatitis. I am also investigating and characterizing allergen-specific T cell immune responses, activation/memory markers, cytokine release, and gene expression in human asthma, with a goal toward elucidating the differences between allergic asthmatics and allergic nonasthmatics, which may help reveal the mechanisms that underlie the immunopathogenesis of asthma.
- Cho JL*, Ling MF* (contributed equally), et al. Allergic asthma is distinguished by sensitivity of allergen-specific CD4+ T cells and airway structural cells to type 2 inflammation. Science Translational Medicine, 2016;8:359ra132.
- Islam S*, Ling MF* (*contributed equally), Leung J, Shreffler WG, Luster AD. Identification of human CCR8 as a CCL18 receptor. Journal of Experimental Medicine, 2013;210:1889-98.
- Wong JT, Ling M, Patil, S, Banerji A, Long A. Oxaliplatin Hypersensitivity: Evaluation, Implications of Skin Testing, and Desensitization. Journal of Allergy and Clinical Immunology: In Practice, 2014;2:40-5
- Patil, SU, Long AA, Ling M, et al. A protocol for risk stratification of patients with carboplatin-induced hypersensitivity reactions. Journal of Allergy and Clinical Immunology, 2012;129:443-447.
- Kim TW, Hung CF, Ling M, Juang J, He L, Hardwick JM, Kumar S, Wu TC. Enhancing DNA vaccine potency by coadministration of DNA encoding antiapoptotic proteins. Journal of Clinical Investigation, 2003;112:109-17.
- Cheng WF, Hung CF, Chai CY, Hsu KF, He L, Ling M, Wu TC. Tumor-specific immunity and antiangiogenesis generated by a DNA vaccine encoding calreticulin linked to a tumor antigen. Journal of Clinical Investigation, 2001;108:669-78.
- Wang TL, Ling M, et al. Intramuscular administration of E7-transfected dendritic cells generates the most potent E7-specific anti-tumor immunity. Gene Therapy, 2000;7:726-33.