Endocrinology
Kobayashi Laboratory
Endocrine Unit Research Laboratories
Thier Building
50 Blossom Street
Boston,
MA
2114
Phone: 617-724-7448
Fax: 617-726-7543
Email: tkobayashi1@mgh.harvard.edu
Explore This Research Lab
About the Lab
The Kobayashi laboratory uses genetically manipulated mice to study the role of regulatory systems of gene expression during cartilage and bone development. At the genetic and molecular levels, understanding how gene expression is regulated during skeletal cell differentiation is the central question. One of my current interests is to elucidate the role of the posttranscriptional gene regulatory mechanisms through the microRNA pathway in bone development.
Group Members
Principal Investigator
Research Projects
Investigation in roles of miR-140, let-7 miRNAs, miR-17-92 miRNAs in mouse skeletal development and homeostasis.
Roles of histone modifiers in skeletal development and homeostasis.