Common cause of heart attacks in younger adults linked to gene variants
Mutations in genes that direct the production of fibrillar collagens, essential components of blood vessel walls, appear to predispose individuals to SCAD.
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Dr. Mark Lindsay is a cardiologist specializing in Genetic Aortic Disease, Massachusetts General Hospital and Massachusetts General Hospital for Children Assistant Professor of Medicine, Harvard Medical School.
Departments, Centers, & Programs:
Clinical Interests:
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Mass General Heart Center: Thoracic Aortic Center
55 Fruit St.
Boston, MA 02114
Phone: 866-644-8910
Medical Education
American Board Certifications
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My research interest is the clinical expression and molecular etiology of human arterial disease. In my research I utilize human and murine genetics as well as animal modeling to investigate the etiology and pathologic progression of inherited and sporadic arterial diseases. Through this work I hope to discover better diagnostics and novel therapies for patients with these serious conditions.
My research biography is available at: https://www.ncbi.nlm.nih.gov/myncbi/browse/collection/51274044/?sort=date&direction=descending
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Mutations in genes that direct the production of fibrillar collagens, essential components of blood vessel walls, appear to predispose individuals to SCAD.
The results could also lead to new strategies to prevent and treat enlarged aortas.
Tapping expertise from MassGeneral Hospital for Children, the Myhre Syndrome Foundation launched its inaugural conference on July 10-11, 2021.
Tapping expertise from MassGeneral Hospital for Children (MGHfC), the Myhre Syndrome Foundation (MSF) launched its inaugural conference on July 10 - 11, 2021.
At 16, Anna Young was diagnosed with Myhre Syndrome, a very rare genetic condition. Since coming to the Myhre Syndrome Clinic at MGHfC, she has found her place in the world and learned the skills to thrive as a young adult.
A Massachusetts General Hospital research team has identified a nucleoprotein complex that is responsible for breaking down the arterial wall in aortic aneurysm.