Photo of Jagmeet (Jag) P. Singh, MD, PhD

Jagmeet (Jag) P. Singh, MD, PhD

  • Associate Chief, Cardiology Division


Accepting New Patients


Jag Singh, MD, PhD, is the Associate Chief of the Cardiology Division and the Roman W. DeSanctis Endowed Chair in Cardiology. He is a Professor of Medicine at Harvard Medical School and also the Founding Director of the Resynchronization and Advanced Cardiac Therapeutics Program, at the Massachusetts General Hospital Heart Center.




Centers & Specialties

Heart Center

Clinical Interests
  • Cardiac resynchronization therapy for heart failure
  • Catheter ablation of atrial fibrillation
  • Implantable cardioverter defibrillators (ICD) and pacemakers
  • Syncope
  • Drug-induced arrhythmias
  • Long QT syndrome
  • Cardiac arrhythmia
Medical Education
  • MD, BJ Medical College
  • PhD, Oxford University
  • Residency, Massachusetts General Hospital
  • Fellowship, Massachusetts General Hospital
Board Certifications
  • Cardiovascular Disease
  • Clinical Cardiac Electrophysiology
Foreign Languages
  • Hindi
  • Panjabi
  • Marathi
  • Boston: Massachusetts General Hospital
Insurances Accepted
  • Aetna Health Inc.
  • AllWays Health (NHP) - ACD
  • AllWays Health (NHP) - PBO
  • Beech Street
  • Blue Cross Blue Shield - Blue Care 65
  • Blue Cross Blue Shield - Indemnity
  • Blue Cross Blue Shield - Managed Care
  • Blue Cross Blue Shield - Partners Plus
  • BMC HealthNet Mass Health MCO/ACO
  • Cigna (PAL #'s)
  • Commonwealth Care Alliance
  • Fallon Community HealthCare
  • Great-West Healthcare (formally One Health Plan)
  • Harvard Pilgrim Health Plan - ACD
  • Harvard Pilgrim Health Plan - PBO
  • Health Care Value Management (HCVM)
  • Humana/Choice Care PPO
  • Maine Community Health Options (MCHO)
  • MassHealth
  • Medicare
  • Medicare - ACD
  • OSW - Connecticut
  • OSW - Maine
  • OSW - New Hampshire
  • OSW - Rhode Island
  • OSW - Vermont
  • Private Health Care Systems (PHCS)
  • Railroad Medicare
  • Railroad Medicare - ACD
  • Senior Whole Health
  • TriCare
  • Tufts Health Plan
  • Unicare
  • United Healthcare (non-HMO) - ACD
  • United Healthcare (non-HMO) - PBO
  • Well Sense Pediatrics

Note: This provider may accept more insurance plans than shown; please call the practice to find out if your plan is accepted.

Patient Age Group
Provider Gender


Jag Singh, MD, DPhil, is the Associate Chief of the Cardiology Division and the Roman W. DeSanctis Endowed Chair in Cardiology.  He is a Professor of Medicine at Harvard Medical School and also the Founding Director of the Resynchronization and Advanced Cardiac Therapeutics Program, at the Massachusetts General Hospital Heart Center. Dr. Singh received his medical degree from BJ Medical College, Pune University, India. He completed his internal medicine residency, cardiology and cardiac electrophysiology fellowships at Mass General. He also earned a doctorate from Oxford University, a master of science in clinical investigation from MIT-Harvard and a research fellowship at the Framingham Heart Study.

Dr. Singh's research interests are in clinical cardiac electrophysiology. Dr. Singh is the national & global principal investigator on 5 ongoing multi-center clinical trials in device therapy for heart failure and catheter ablation for atrial fibrillation. He is also  a member of several steering committees for  multicenter research studies. Much of his current efforts are  focussed on the delivery of cardiovascular care while adapting to health care reform, population health initiatives and furthering the digital footprint of the Heart Center.  Dr. Singh is on the editorial board of several medical journals, Deputy Editor of the Journal of American College of Cardiology: Clinical EP  and editor-in-chief of the Current Treatment Options in Cardiovascular Medicine. Dr. Singh is an internationally recognized speaker and frequently gives lectures at national/ international educational forums. Dr. Singh has over 250 publications inclusive of original research articles, text book chapters, review articles and editorials. He has edited a Textbook on Imaging in Electrophysiology. 

Research & Publications

Research Summary
  • Risk stratification for sudden cardiac death and worsening heart failure. Dr. Singh has done extensive work with the Framingham Heart Study and the MADIT Study group and published several landmark manuscripts.
  • Patient selection and predicting response to cardiac resynchronization therapy. Dr. Singh has developed and built a new multidisciplinary program at Massachusetts General Hospital to care for patients with heart failure and implanted devices. His research work has led to the development of a novel response score to predict clinical outcome in this patient group.
  • Coronary venous anatomy and novel ventricular lead implantation strategies. Dr. Singh has used novel rotational venography and imaging techniques to propose and substantiate new coronary venous anatomy classification and redefine the best views for lead implantation. Dr. Singh published on the importance of left ventricular lead position and developed new implantation protocols, some of which are being tested prospectively in clinical studies.
  • Image integration strategies and multimodality imaging for cardiac resynchronization therapy. Dr. Singh has done some novel work integrating computed tomography, ultrasound and fluoroscopy to create better clinical strategies to facilitate device implantation.
  • Device diagnostics and remote monitoring in heart failure patients. Dr. Singh's recent work has focused on the use of remote monitoring and device diagnostics to prognosticate and manage patients.
  • Newer drugs and catheter ablation strategies of atrial fibrillation. Dr. Singh is actively engaged in research examining newer drug therapies for atrial fibrillation. His research interests also examine novel approaches to enhance patient selection, imaging and ablative techniques for treating atrial fibrillation.

View my most recent publications at PubMed

Select Publications:

  • Singh JP et al. Abnormal rate adaptation of the QT interval is associated with hypertensive left ventricular hypertrophy. J Am Coll Cardiol 1997;29:778.
  • Singh JP et al. Heritability of heart rate variability: the Framingham Heart Study. Circulation, 1999;99: 2251.
  • Singh JP et al. Factors influencing appropriate firing of the implanted defibrillator for ventricular tachycardia/fibrillation: findings from MADIT II. J Am Coll Cardiol 2005 46:1712.
  • Singh JP et al. Coronary venous anatomy: a segmental approach to aid cardiac resynchronisation therapy. J Am Coll Cardiol . 2005;46:68.
  • Heist EK et al, Singh JP. Usefulness of a Novel Response Score to Predict Hemodynamic and Clinical Outcome from Cardiac Resynchronization Therapy. Am J Cardiol. 2006;97:1732-6.
  • Singh JP, et al. Left ventricular lead electrical delay predicts response to cardiac resynchronization therapy Heart Rhythm. 2006;3:1285.
  • Tournoux F et al, Singh JP. Echocardiographic Measures of Acute Hemodynamic Response after Cardiac Resynchronization Therapy Predict Long-term Clinical Outcome. European Heart Journal, 2007;28:1143.
  • Singh JP. Electrical Therapy for Advanced Heart Failure: Is it Time for a Multidisciplinary Approach or a New Subspecialty? Expert Rev Cardiovasc Ther. 2007;5:811.
  • Singh JP et al. Patient selection and classification for atrial fibrillation ablation: Thinking beyond duration. 2009;6:1522.
  • Upadhyay G et al, Singh JP. Cardiac Resynchronization in Patients with Atrial Fibrillation: a Meta-analysis of Prospective Cohort Studies. J Am Coll Cardiol 2008;52:1239.

News & Events

  • Progressive Digital and Wearable Landscape Expands Horizons for Continuous Patient Care

    In an editorial, Jagmeet Singh MD PhD highlights the progressive trend in connected devices to manage patient care and the need for a cultural shift electrophysiologists’ clinical practice.

  • Atrial Fibrillation and Heart Failure Prevention: Do We Need a Risk Score?

    Atrial fibrillation (AF) and heart failure (HF) are individual serious conditions with shared molecular and structural changes. Shared predisposition suggests a common pathophysiology that should be probed to understand the overlap and use it to optimize care

  • Integrated Care for Better Outcomes: The Multidisciplinary Resynchronization Therapy Program

    New research from the CRT Program within the Institute for Heart, Vascular, and Stroke Care at Massachusetts General Hospital shows that providing multidisciplinary integrated CRT care improves patient outcomes.

  • Mass. General Patient First in New England to Receive Nerve Stimulator to Treat Heart Failure

    Anita Levy, 59, arrived at Massachusetts General Hospital in 2012 with severe heart failure. The mother of four, grandmother of eight and wife of 38 years, was starting to lose hope. After trying a number of therapies without success, her doctors informed her she was a candidate for a new clinical trial.

  • Improved Clinical Outcomes for CRT Patients

    Jagmeet Singh, MD, Director of the Cardiac Resynchronization Therapy Program at the Massachusetts General Hospital Heart Center, discusses his team’s recent study about multidisciplinary care (MC) versus conventional care (CC) in CRT (cardiac resynchronization therapy) patients.

  • Treating Heart Failure in the 21st Century

    February is American Heart Month, and the spotlight is on heart health. Throughout this month, we will be featuring articles including discussions with physicians in the Massachusetts General Heart Center to learn more about the topics surrounding heart disease, the leading cause of death in the U.S. for both men and women.

  • At-home heart care

    MGH Hotline 07.24.09 Doctors at the MGH Heart Center have implanted the first patient with a new device they hope will reduce hospitalizations for heart failure.

  • At home heart failure care

    A new clinical trial at the Massachusetts General Hospital Heart Center gives patients the power to monitor their hearts and change their medication dosing daily to prevent the symptoms of heart failure.

  • A strongman's second chance

    In 2008, the Massachusetts General Hospital Transplant Center completed the most heart transplants in the region. Personal trainer and strongman competitor, Jim Murphy, is one shining example of the great successes of the program.


  • Resynching a Heart -- and a Life: Bob's Story

    Jane and Bob Wass have been married for 59 years and rarely leave one another’s side. Jane left Bob at home for 35 minutes one afternoon and, when she returned, she found Bob had collapsed from a heart attack. They went to Mass General, where they learned he had a dyssynchrony. Bob's care team implanted a pacemaker and defibrillator, and he experienced an immediate improvement in his health. The team continues to monitor Bob’s heart remotely.


Cardiac Unit Associates
55 Fruit Street
Boston, MA 02114-2696
Phone: 617-724-2142
Fax: 617-726-3852

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