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The Mass General Corrigan Minehan Heart Center brings together cardiologists and heart specialists from surgery, anesthesia, imaging and nursing to provide patients with a personal care team to treat their condition. Learn how our services impact patient care.
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A team led by Massachusetts General Hospital (MGH) investigators has found that activity of an important signaling pathway increases with aging and with heart failure and that inhibiting that pathway can improve cardiac function in mouse models.
Massachusetts General Hospital investigators have discovered one way that sleep protects against cardiovascular disease by preventing the buildup of arterial plaques called atherosclerosis.
A research team at the Broad Institute, Massachusetts General Hospital and Harvard Medical School reports a new kind of genome analysis that could identify large fractions of the population who have a much higher risk of developing serious common diseases, including coronary artery disease, breast cancer, or type 2 diabetes.
A Massachusetts General Hospital study finds that patients with both HIV infection and heart failure whose antiretroviral regimen includes protease inhibitors may be at greater risk for worsening of heart failure and cardiovascular death than patients with HIV taking non-protease-inhibitor-based regimens.
A study conducted among patients at Massachusetts General Hospital and Brigham and Women’s Hospital found that virtual follow-up visits for patients with hypertension appeared just as effective as in-person office visits in helping maintain blood pressure control.
A study by investigators at Beth Israel Deaconess Medical Center, Massachusetts General Hospital, and the Benson-Henry Institute for Mind Body Medicine identified genes associated with the body’s response to relaxation techniques and sheds light on the molecular mechanisms by which these interventions may work to lower blood pressure.
A multi-institutional study led by a Massachusetts General Hospital physician supports the value of a biomarker to accurately diagnose or rule out acute heart failure in patients seen for shortness of breath at hospital emergency departments.
Many patients who experience a type of heart attack known as spontaneous coronary artery dissection may benefit most from a conservative approach to treatment, rather than more invasive procedures. A scientific statement reviewing current knowledge and best practices for SCAD treatment – put together by a collaborative working group from multiple institutions including Massachusetts General Hospital – was published today in the American Heart Association journal, Circulation.
A research team led by investigators from Massachusetts General Hospital has shown, for the first time, that it may be possible to nonsurgically treat or even prevent the damage to a major heart valve that often occurs after a heart attack.
An analysis of diagnostic test results from a trial comparing anatomic with functional testing as an initial diagnostic strategy for patients with chest pain found that CT angiography better predicted the risk for future cardiac events than did measures of exercise tolerance or restricted blood flow to the heart muscle.
A study by a multi-institutional research team has tracked the long-term incidence of death following ischemic and bleeding events occurring in patients more than one year after placement of a coronary stent.
A study led by Massachusetts General Hospital and Icahn School of Medicine at Mount Sinai investigators has linked, for the first time in humans, activity in a stress-sensitive structure within the brain to the risk of subsequent cardiovascular disease.
A study led by Massachusetts General Hospital investigators has found that, even among those at high genetic risk for heart disease, following a healthy lifestyle can cut in half the probability of a heart attack or similar event.
In papers receiving advance online publication in Nature Genetics, two international multi-institutional research teams, co-led by investigators at Massachusetts General Hospital, describe identifying a total of 44 novel gene sites associated with hypertension or high blood pressure.
More than one quarter of heart attack patients who are normally treated with stents to re-open their blocked arteries might be able to forgo this procedure and receive anti-thrombotic medications only, according to results of a pilot study.
A study from an international research team finds that familial hypercholesterolemia – a genetic condition that causes greatly elevated levels of LDL cholesterol throughout life – accounts for less than 2 percent of severely elevated LDL in the general population but also increases the risk of coronary artery disease significantly more than does elevated LDL alone.
MGH researchers have taken initial steps toward the creation of bioengineered human hearts using donor hearts stripped of components that would generate an immune response and cardiac muscle cells generated from induced pluripotent stem cells, which could come from a potential recipient.
A new study led by Massachusetts General Hospital MGH investigators finds that heart failure patients who underwent bariatric surgery to treat morbid obesity had a significant reduction in the incidence of heart failure exacerbation – a dangerous, sudden worsening of symptoms – in the two years following surgery.
The most modern clinical trial to compare the use of carotid-artery stenting with carotid endarterectomy for the prevention of strokes in asymptomatic patients with serious narrowing of the carotid artery finds no significant differences in outcomes between the two procedures over a period of up to five years.
Four tiny segments of RNA appear to play critical roles in controlling cholesterol and triglyceride metabolism. An MHG -based research team has discovered how these microRNAs can reduce the expression of proteins playing key roles in several cardiovascular risk factors.
An international research collaboration led by MGH investigators has identified the first gene in which mutations cause the common form of mitral valve prolapse, a heart valve disorder that affects almost 2.5 percent of the population.
The current guidelines for determining whether patients should begin taking statins to prevent cardiovascular disease are more accurate and more efficient than an earlier set of guidelines in assigning treatment to adults at increased risk for cardiovascular events and identifying those whose low risk rules out the need to take statins.
A lightweight, portable system developed by an MGH research team can produce the potentially life-saving gas nitric oxide from the air by means of an electrical spark.
By combing through the DNA of more than 100,000 people, researchers at Broad Institute, Massachusetts General Hospital, and elsewhere have identified rare, protective genetic mutations that lower the levels of LDL cholesterol — the so-called “bad” cholesterol — in the blood.
Two international research studies, both led by investigators affiliated with MGH and the Broad Institute, have uncovered new information about genes that may increase the risk of serious cardiac arrhythmias.
By scouring the DNA of thousands of patients, researchers have discovered four rare gene mutations that not only lower the levels of triglycerides but also significantly reduce a person’s risk of coronary heart disease
New data showing that high-dose atorvastatin can reduce periodontal inflammation in as little as four weeks suggests a new mechanism of action for statins.
College football players, especially linemen, may develop high blood pressure over the course of their first season, according to a small study in the American Heart Association’s journal Circulation.
A new clinical trial is now underway at the Massachusetts General Hospital to investigate whether combining two endovascular catheter-based procedures will improve the long-term outcome in the treatment of atrial fibrillation, the most common heart rhythm disorder. Mass General is the first hospital in New England – and only the second in the nation – to pair renal artery sympathetic denervation with pulmonary vein isolation (PVI) for patients with atrial fibrillation and hypertension.
Incorporating coronary CT angiography into the initial evaluation of low-risk patients coming to hospital emergency departments with chest pain appears to reduce the time patients spend in the hospital without incurring additional costs or exposing patients to significant risks.
Massachusetts General Hospital has moved into the number one spot on the 2012-13 U.S. News & World Report’s “America’s Best Hospitals” list.
A new study finds that the use of drug-eluting stents after angioplasty bears little relationship to patients' predicted risk of restenosis (reblockage) of the treated coronary artery, the situation the devices are designed to prevent.
A new study finds that participating in these races actually is associated with a relatively low risk of cardiac arrest, compared to other forms of athletics. The study also identifies bystander-initiated cardiopulmonary resuscitation as a key factor in patient survival.
A new device that combines two microimaging technologies can reveal both the detailed anatomy of arterial linings and biological activities that, in coronary arteries, could indicate the risk of heart attacks or the formation of clots in arterial stents.
Adding regular testing for blood levels of a biomarker of cardiac distress to standard care for the most common form of heart failure may significantly reduce the incidence of cardiovascular complications, a new MGH study finds.
A new report from MGH scientists and colleagues around the world finds that common variants in 28 regions of DNA are associated with blood pressure in human patients. Most of the identified regions were completely unsuspected, and several may lead to a totally new class of hypertension drugs.
Measuring the levels of small molecules in the blood may be able to identify individuals at elevated risk of developing type 2 diabetes as much as a decade before symptoms of the disorder appear.
An international research collaboration has identified 13 new gene sites associated with the risk of coronary artery disease and validated 10 sites found in previous studies. Several of the novel sites discovered do not appear to relate to known risk factors, suggesting previously unsuspected mechanisms for cardiovascular disease.
Two papers in the current issue of Nature describe 95 gene variations that contribute to cholesterol and triglyceride levels and reveal the unexpected role of a metabolic pathway in lipid metabolism.
Mass General researchers unveiled a non-invasive ultrasound technique to help detect heart muscle damage in breast cancer patients undergoing chemotherapy.
Researchers found that heart and circulation ultrasounds are an important tool in assessing the risk of heart disease in women who are obese or have metabolic syndrome.
An international research consortium has identified four common gene variants that are associated with blood levels of vitamin D and with an increased risk of vitamin D deficiency.
Heart attacks declined by 24 percent within a large, ethnically diverse, community-based population since 2000, and the relative incidence of serious heart attacks that do permanent damage declined by 62 percent, according to a study in the current issue of the New England Journal of Medicine.
Using a system that analyzes blood samples with unprecedented detail, a team led by MGH researchers has developed the first "chemical snapshot" of the metabolic effects of exercise.
MGH researchers have identified tiny segments of RNA that may play an important role in the body's regulation of cholesterol and lipids.
Long-term anabolic steroid use may weaken the heart more than previously thought and may increase the risk of heart failure, according to a study led by MGH investigator Aaron Baggish, MD.
Mass General researchers are spearheading an international effort to study optical coherence tomography (OCT), an imaging technology that could help doctors identify the vulnerable coronary plaques that cause heart attacks.
A new study by researchers at the MGH Heart Center found the addition of electrocardiogram testing to the standard medical history and physical examination for young athletes may better identify key cardiovascular abnormalities responsible for sports-related sudden death.
An international research team has identified a common gene variant associated with a form of the irregular heartbeat called atrial fibrillation that is seen in younger individuals with no other heart disease.
A team of Harvard Stem Cell Institute scientists at Massachusetts General Hospital and collaborators at Harvard’s School of Engineering and Applied Sciences has taken a giant step toward the possibility of using human stem cells to repair damaged hearts.
A team of researchers led by Massachusetts General Hospital radiologists has developed a computed-tomography-based protocol that identifies both narrowing of coronary arteries and areas of myocardial ischemia - restricted blood flow to heart muscle tissue - giving a better indication of clinically significant coronary artery disease.
Levels of a biomarker used in the diagnosis of heart attacks are almost universally elevated in patients who have undergone coronary-artery bypass grafting (CABG) and, when markedly elevated, powerfully predict the risk of complications.
Measurement of known biomarkers of cardiovascular disease slightly improves the ability to predict future heart attack or stroke in healthy individuals, but not enough to change preventive therapies.
A common electrocardiogram finding that has largely been considered insignificant may actually signal an increased risk of atrial fibrillation, the future need for a permanent pacemaker and an increased risk for premature death.
Scientists from Massachusetts General Hospital (MGH), as part of a major international research collaboration, have associated common variants in eight regions of DNA with blood pressure levels in human patients. Six of the identified regions have not previously been implicated in blood pressure regulation.
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Risk factors for heart disease include smoking, high blood pressure, diabetes, family history of heart disease and high cholesterol. Learn what you can do to overcome your risk for heart disease.
Mass General Heart Center physicians offer a new technique to prevent blood clots in the part of the heart called the left atrial appendage. This innovative procedure shows promise in preventing strokes in patients with atrial fibrillation, freeing them from dependence on blood thinning medications.
Malissa Wood, MD, Co-Director of the Corrigan Women's Heart Health Program at the Massachusetts General Hospital Heart Center describes the heart attack symptoms that are unique to women, and why treatment of heart disease should be gender-specific.
Sekar Kathiresan, MD, Director of Preventive Cardiology at the Massachusetts General Hospital Heart Center says counteracting your genetic risk is within your control. Learn more about coronary artery disease, who is most at risk and about Mass General's Heart Attack Prevention Program, focused on people with a family history of the disease.
Aaron Baggish, MD, Associate Director for the Cardiovascular Performance Program at the Massachusetts General Hospital Heart Center explains how heart problems are diagnosed in highly active people and how Mass General specialists help them exercise safely to reduce the risk of heart attack.
Stephanie Moore, MD, cardiologist in the Heart Failure and Cardiac Transplant Program at the Mass General Heart Center says if a close relative suffered from heart failure, you should be screened for other health issues that can put you at higher risk. Learn more about the early signs of heart failure and the various treatments available, from medications to pacemakers to transplants.
Since 1811, people have counted on Mass General for answers, innovations and medical leadership. As our third century dawns, we remain ready to serve.
Dr. Patrick Ellinor, cardiologist at the Mass General Heart Center, says you should discuss your condition with your doctor, since many people who could benefit from specific treatments are not aware of them.
On June 28, 2012, <a href="http://www.massgeneral.org/about/newsarticle.aspx?id=3632" target="blank">nine cardiac ECMO patients came together</a> with MGH Cardiac Surgery clinicians for a reunion at the Paul S. Russell, MD Museum of Medical History and Innovation.
Thor Sundt, MD, chief of cardiac surgery and director of the Corrigan Minehan Heart Center, talks about heart valve options for patients undergoing heart valve surgery.
Jonathan Passeri, MD, co-director of the Mass General Heart Valve Program and director of Interventional Echocardiography, talks about aortic valve stenosis and answers common questions about symptoms to look out for and treatment options.
A young man's quest to find a cure for his epileptic seizures takes him on a journey from Albania to Boston.
Courtney first came to Mass General at the age of 8 when she was diagnosed with bone cancer in her leg. Mass General treated and cured her as child, but the chemotherapies used put her at risk for a weakened heart. When Courtney wanted to start a family, she came back to Mass General and met with specialists who coached her through two pregnancies, ensuring that she remained healthy and also delivered two healthy babies.
Jane and Bob Wass have been married for 59 years and rarely leave one another’s side. Jane left Bob at home for 35 minutes one afternoon and, when she returned, she found Bob had collapsed from a heart attack. They went to Mass General, where they learned he had a dyssynchrony. Bob's care team implanted a pacemaker and defibrillator, and he experienced an immediate improvement in his health. The team continues to monitor Bob’s heart remotely.
At age 16, Jack Cadigan appeared to be a healthy, athletic high school student, playing on his school’s basketball team. That summer, Jack volunteered at a medical clinic in Haiti where they discovered he had an issue with his heart. He came to Mass General where Dr. Ami Bhatt diagnosed him with an atrial septal defect, which was repaired through surgery. Jack immediately noticed a big difference in his health, not realizing how limited he was before the surgery.
Ami Bhatt, MD, director of the Adult Congenital Heart Disease Program at Massachusetts General Hospital, discusses the prevention of atherosclerotic cardiovascular disease in adults with congenital heart disease.
Dolly Lakkis—a business owner, optician and competitive dancer—didn’t have time to be sick. When mitral valve disease started to affect the quality of her life, she turned to a team of specialists at the Corrigan Minehan Heart Center at Massachusetts General Hospital. Dolly’s doctors were able to repair her damaged heart valve with minimally invasive surgery that got her back on her feet—and back on the dance floor—as quickly as possible.
Ami Bhatt, MD, director of the Adult Congenital Heart Disease Program, discusses her mentors and their approach to patient care — in honor of the 100th anniversary of Cardiology at Mass General and Paul Dudley White, who founded our Cardiology Division in 1916.
In honor of the 100th anniversary of Cardiology at Mass General, Malissa J. Wood, MD, co-director of the Corrigan Women's Heart Health Program, discusses the legacy of Paul Dudley White, who founded our Cardiology Division in 1916.
In 2016, the 15th meeting of the Paul Dudley White Society, under the leadership of Barry London, MD, president of the society, and Anthony Rosenzweig, MD, chief of the Cardiology Division, celebrated the 100th anniversary of the founding of the Cardiac Unit and the legacy of Dr. White.
Katrina Armstrong, MD, chair of the Department of Medicine and physician in chief at Massachusetts General Hospital, delivered introductory remarks to members of the Paul Dudley White Society for the celebration of the 100th anniversary of the hospital's Cardiology Unit.
Malissa Wood, MD, answers some commonly asked questions about Spontaneous Coronary Artery Disease, or SCAD.
Allison Renna, triathlete and mother of three, suffered a heart attack at the age of 36. In this video, Allison talks about the cardiac episode that brought her to Mass General, and her experience with the Cardiovascular Performance Program.
Ted Kakas, international-level masters rower, has suffered from atrial fibrillation and coronary artery disease. In this video, Ted talks about his appreciation for the Mass General Cardiovascular Performance Program as both an athlete and a patient. Learn how Dr. Baggish and his team are able to work with to Ted keep him out on the water.
Chris Duffy, a professional cyclist, was diagnosed with heart failure at just 23. At age 29, he underwent a heart transplant. In this video, Chris talks about the Mass General Cardiovascular Performance Program and how Dr. Aaron Baggish and his team have been able to keep him on his bike.
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