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Dr. Bredella is Professor of Radiology at Harvard Medical School and a musculoskeletal radiologist at the Massachusetts General Hospital (MGH) where she serves as the Director of Musculoskeletal Research. She received her MD degree from the University of Hamburg, Germany in 1997. After a postdoctoral research fellowship at the Osteoporosis and Arthritis Research Group (OARG) in the Department of Radiology at the University of California, San Francisco (UCSF), she completed a residency in diagnostic radiology at UCSF where she also served as Chief Resident. She pursued a fellowship in musculoskeletal imaging and interventions at MGH. After completing fellowship training in 2005, she joined the faculty of MGH and Harvard Medical School.
Dr. Bredella established a multidisciplinary clinical research program in the area of metabolic imaging that combines innovative translational, clinical, and outcomes research. Her research focuses on the effects of different fat depots on bone metabolism in states of under- and overnutrition. Dr. Bredella has developed new imaging techniques to quantify brown adipose tissue, intramyocellular lipids (IMCL), intrahepatic lipids, and muscle mitochondrial function and examined their effects on bone, insulin resistance and cardiovascular risk in subjects with obesity, insulin resistance, growth hormone disorders, and anorexia nervosa (AN). Since joining the faculty at MGH, she has been continuously grant funded as principle investigator by the NIH. Dr. Bredella is on the Editorial Boards of the Journal of Bone and Mineral Research (JBMR) and Skeletal Radiology and is a Founding Editorial Board member of the Journal of Hip Preservation Surgery. She is the recipient of multiple awards, including the Annual Investigator Award from the Academy of Radiology Research and the Presidents Medal of the International Skeletal Society. She serves on the Board of Directors of the Academy of Radiology Research.
View my most recent publications at PubMed
Research at the MGH is interwoven throughout more than 30 departments, centers and units and is conducted with the support and guidance of the MGH Research Institute. The Research Roundup is a monthly series highlighting studies, news and events.
Excess fat around the belly has recently been identified as a risk factor for bone loss. A new study by Mass General radiologists has determined that excess liver and muscle fat also may be detrimental to bone.
Visceral, or deep belly, obesity is a risk factor for bone loss and decreased bone strength in men, according to a study presented today at the annual meeting of the Radiological Society of North America.
In a new study presented today at the annual meeting of the Radiological Society of North America, growth hormone replacement for six months was found to increase bone formation in abdominally obese women.
A study presented at the annual meeting of the Radiological Society of North America found that having too much internal abdominal fat may have a damaging effect on bone health.
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