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Lipid Metabolism Unit
The Lipid Metabolism Unit at Massachusetts General Hospital engages in both clinical and research activities centering on the role of lipids and lipoproteins in atherosclerosis (heart disease).
The research activities of the Lipid Metabolism Unit are centered on cholesterol trafficking in and out of cells and the proteins that control this movement. NIH-funded studies support current investigations into the biology of the ABCA family of lipid transporters, scavenger receptors and inflammatory signaling pathways that play a role in atherosclerosis and Alzheimer's disease.
The Lipid Metabolism Unit is tightly linked into the Center for Computational & Integrative Biology (CCIB), which has developed a new program in Translational Medicine, headed by Mason Freeman MD, is designed to take novel therapeutic molecules generated in either the CCIB laboratories or elsewhere in academia or industry and move those treatments into first-in-man therapeutic trials.
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