The CSIBD Clinical Core provides an infrastructure to facilitate the translation of basic research findings into a clinical setting.
Research & Clinical Trials
Our laboratory seeks to gain new insights into the molecular pathogenesis of tumors of the GI tract. Our particular areas of interest are colon cancer, neuroendocrine tumors, angiogenesis, hypoxia, hereditary cancers, and genetic instability. We seek to identify molecular targets that can ultimately guide therapeutic strategies.
My lab is focused on understanding the complex interaction between the immune system and cancer, focusing on the balance between protective antitumor immunity and immunotherapy toxicities.
Our laboratory has been involved in uncovering the mechanisms by which hepatitis viruses, particularly hepatitis C, persist in the liver and cause liver damage.
The Human Genetics and Microbiome Core strives to provide the CSIBD community with the power of current and emerging ‘omics technology to accelerate research on multiple aspects of IBD and other digestive diseases.
Our core provides CSIBD with cost-effective access to crucial instruments, reagents, protocols, training and education.
At the Mass General Weight Center, we believe that treatments for obesity that are safe and effective will be discovered only through ongoing research to find the answers to these and other questions.
Understanding the human immune response against viruses, with a focus on T-cell responses targeting human hepatotropic viruses (Hepatitis C Virus (HCV), Hepatitis B Virus (HBV), HCV/HIV co-infection). Establishing the groundwork for rational design of antiviral vaccines and immunotherapies.
Provides investigators with the technical support, expertise and access to instrumentation for morphological and cell biological studies related to IBD.
Our research focuses on understanding the pathogenesis of nonalcoholic fatty liver disease and nonalcoholic steatohepatitis (NASH), the interaction between obstructive sleep apnea (OSA) and NASH, and the influence of NASH on lipid metabolism and cardiovascular risk factors.
Learn More About Us
Discoveries into the underlying mechanisms of gastrointestinal diseases and new treatment approaches are facilitated by a large research base within Massachusetts General Hospital and the NIH-funded Center for the Study of Inflammatory Bowel Disease.