New research published in PNAS that was led by investigators at Massachusetts General Hospital (MGH) and the University of Geneva (UNIGE) provides insights on why some types of colorectal cancer don’t respond to immune checkpoint inhibitors and offers a strategy to overcome their resistance.
Explore This Treatment
This year over 50,000 men and women in the U.S. will die from colon cancer. And many could have been saved. When colon cancer is detected early, there is a 90% survival rate. When it's not, that number is less than 50%. Starting at age 50, you should have a colonoscopy at least once every ten years to screen for polyps and cancer. Colon cancer can be beaten. Prevention and early detection are your best weapons.
We offer the most advanced colon cancer screenings and treatments available. Our world-renowned specialists can provide the comprehensive care and peace of mind you'll only find at one of the world's leading hospitals.
Talk to your doctor about scheduling your colorectal cancer screening at Massachusetts General Hospital. Then call (617) 726-2426 or request an appointment online.
Please visit our doctors page for a list of our gastroenterologists.
High-risk Cancer Genetics Program
Some individuals and families are at much higher risk of specific gastrointestinal cancers. The following factors can increase your risk of cancer:
- Personal or family history of colon polyps or cancer
- Familial Adenomatous Polyposis (Gardner's Syndrome)
- MYH-Associated Polyposis (MAP)
- Hereditary Nonpolyposis Colorectal Cancer (HNPCC) syndrome
- Lynch Syndrome
- Hamartomatous Polyposis syndromes such as Peutz-Jeghers or Juvenile Polyposis
- Personal or family history of endometrial cancer or ovarian cancer (which can be associated with colon cancer)
- Family history of gastric cancer
- Family history of pancreatic cancer
The High-Risk GI Cancer Genetics program evaluates individuals with a strong family history of gastrointestinal cancer, especially colon cancer. Our goal is to serve not only patients, but also their families and referring physicians with up-to-date recommendations surrounding the complicated issues of clinical screening as well as genetic testing.
We encourage referrals of patients, their affected family members, and also those at-risk in their families. Recommendations will be made for clinical screening and surveillance, and when appropriate, genetic testing will be offered.
We have ongoing clinical trials in many of these areas.
Genetic CounselorsKristen M. Shannon, MS
Devanshi Patel, MS
Gayun Chan-Smutko, MS
Janette Lawrence, MS
Michele Gabree, MS
Endoscopic Procedures During COVID-19
- Sep | 10 | 2021
“Each morning when we’d arrive at the police barricades, people would be standing there with pictures of their loved ones, asking us to look for them,” Susan Diehl says. “Hours later, after a hard shift when we were ready to get back on the shuttle bus, they were still there—waiting for word.”
- Press Release
- Aug | 27 | 2021
A new health and economic model clearly shows why it’s imperative that food manufacturers reduce the amount of added sugar in their products.
- Jul | 12 | 2021
Immunotherapy is a cancer treatment that works by boosting the body’s immune system. Some patients achieve full remission, meaning all signs of their cancer have disappeared.
- Press Release
- Jul | 8 | 2021
Las puntuaciones de riesgo genético podrían mejorar la identificación clínica de los pacientes con mayor riesgo de infarto
Un equipo descubrió recientemente que la aplicación de la PRS puede identificar a los pacientes de riesgo que actualmente no se identifican mediante las evaluaciones clínicas estándar.
- Press Release
- Jul | 2 | 2021
Using a method developed for HIV, researchers have identified stable T cell vaccine targets in SARS-CoV-2.