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About the Lab

The National Heart, Lung & Blood Institute ARDS Network Clinical Coordinating Center resides in the Massachusetts General Hospital Biostatistics Unit under the direction of David Schoenfeld, PhD. We coordinate the design, execution and interpretation of multicenter clinical trials of ARDS treatments that are carried out in more than 40 hospitals (organized into 12 clinical sites).

The ARDS Network has completed eight randomized controlled trials. B. Taylor Thompson, MD, has a major role in the design and management of these trials and has held three Investigational New Drug Applications with the Food and Drug Administration on behalf of the ARDS Network. Five of our trials have been published in The New England Journal of Medicine, and two are considered landmark trials of lung-protective strategies.

Research Projects

Statins for Acutely Injured Lungs from Sepsis (SAILS)

We are coordinating a 1,000-patient trial of rosuvastatin for ARDS and acute lung injury due to sepsis. Increasing evidence suggests the substantial anti-inflammatory effects of statins may lead to improved outcomes in critically ill patients with severe infections. This study will evaluate the survival rates of patients treated with rosuvastatin in comparison to those treated with placebo.


Click here to view a list of publications from this investigator

Group Members

Principal Investigator
David Schoenfeld, PhD

Medical Director & Co-Principal Investigator
B. Taylor Thompson, MD

Project Manager
Nancy Ringwood, RN, CCRA

Study Coordinator
Katie Oldmixon, RN