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The Mansour lab investigates the critical molecular mechanisms responsible for host immune responses to life-threatening fungal pathogens. Our studies focus on neutrophils, the first line of defense against bacteria and fungi, and the role of fungal carbohydrates in innate immunity. We also perform patient-oriented research by using predictive modeling to assess risk of fungal infection in susceptible patients. Together, these investigations provide the foundation for the development of cellular therapies for infectious diseases as well as improved vaccine strategies. We hope that our research will enhance our understanding of the innate immune mechanisms against fungal pathogens that exist in our everyday environment.
Michael K. Mansour, MD, PhDPrincipal Investigator
Zeina Dagher, PhDStaff Scientist
Paige NegoroResearch Technician
Michelle MartinelliUndergraduate Student
View a full list of the Mansour Lab publications on PubMed.
Mansour LaboratoryMassachusetts General HospitalRooms 1321 and 1328A Gray-Jackson Building55 Fruit Street Boston, MA 02114
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