Accelerating the Path to Effective Treatments

Healey & AMG Center faculty, in partnership with the Northeast ALS (NEALS) Consortium, designed this first-of-its-kind Platform Trial for ALS leveraging input from ALS scientists and clinicians, industry partners, regulators and people living with ALS across the globe. This is a multicenter, double-blind, placebo-controlled, perpetual, adaptive platform trial testing multiple investigational products in parallel until we find safe and effective treatments for people living with ALS.

Latest platform trial news

The HEALEY ALS Platform Trial is a collaborative effort, and enrollment in the trial is available at several sites across the US to bring the trial close to people who want to participate. If you have site-specific questions, please click here to contact the site where you would like to participate. For general inquiries, please contact healeyalsplatform@mgh.harvard.edu.

This groundbreaking approach cuts the time to find an effective treatment in half, decreases costs by a third or more, and is supported by our patients, the FDA, ALS clinicians and scientists and our pharma colleagues.

 Saves TimeSaves Money Merit Cudkowicz, MD, MSc
Director, Sean M. Healey & AMG Center for ALS

New investigational products are added to the HEALEY ALS Platform Trial, supported by pharma, foundation partners, philanthropy, federal and other fundraising initiatives. Academic and industry colleagues are encouraged to engage with the Healey Center ALS Trial Design Team at any time to work together on ALS therapy development. Nominations of products for inclusion in the platform trial will continue on an ongoing, rolling basis.

Information for People with ALS

Information for People with ALS

What people with ALS need to know about the platform trial.

Clinical Trials Enrollment and Coordination

Clinical Trials Enrollment and Coordination

We can help you find and sign up for the trial or study that's right for you.

Subscribe to ALS LINK

Subscribe to ALS LINK

News and updates from the Sean M. Healey & AMG Center for ALS at Mass General.

Thanks to Our Supporters

Thanks to Our Supporters

The HEALEY ALS Platform Trial is supported by many foundations and generous donors.