Welcome to NeuroBlast, the newsletter of neurology, neurosurgery and psychiatry advances from the Massachusetts General Hospital Center for Neurosciences. This issue describes a new Normal Pressure Hydrocephalus (NPH) Evaluation and Management Program; noninvasive brain stimulation techniques to modulate brain activity; and how big data is being used to find new treatments and cures for disease.

Mass General’s NPH Program Offers Comprehensive Evaluation and Treatment of Brain Disorder

"Dr. Arnold, (translational neurology head, Interdisciplinary Brain Center), and Dr. Curry, (attending neurosurgeon), understand that not every condition is black and white, and they took the time to see the shades of gray with my mother,” says Iris, daughter of seventy-nine-year-old patient Tamar. “There aren’t always many happy endings in neurology, but this is certainly one.”

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Noninvasive Brain Stimulation Aims to Reset Circuits to Treat Neuropsychiatric Conditions at Mass General

“Instead of just saying that a patient has depression, or schizophrenia, or stroke, or epilepsy, we focus on transdiagnostic problems such as maladaptive reward processing or amotivation, ineffective inhibitory control or impulsivity, dysexecutive effects such as poor planning or multitasking, et cetera,” says Joan A. Camprodon, MD, PhD, director of the Division of Neuropsychiatry at Mass General.

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Going Big: How Mass General Neurology is Using Big Data for Big Benefits

“We’re building a research environment with tools and methods and procedures that can be shared and multiplied and made scalable enough to have a critical amount of information that could be interpreted for the benefit of patients,” says Alex Sherman, director of the Neurological Clinical Research Institute’s Center for Innovation and Biomedical Informatics.

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