Research Investigator Profile

Fabio Nunes

Fabio P. Nunes, MD

  • Instructor in Neurology,
    Harvard Medical School
  • Assistant in Neurology,
    Massachusetts General Hospital



Research Description

Research interests Meningioma, Multiple meningioma syndrome, Neurofibromatosis, Drug development, Clinical Trials, translational research
Research techniques

Drug screens, tumor cell lines, immunohistochemistry, DNA/RNA extraction and sequencing, microsatellite markers, linkage analysis.

Diseases studied

Familial Multiple Meningioma Syndrome, Sporadic Meningiomas, Neurofibromatosis 2, Schwannomatosis

Selected publications
  1. Nunes FP, MacCollin M. Neurofibromatosis 2 in the pediatric population. J Child Neurol, 18:718-24, 2003.
  2. Nunes FP, Shen Y,Niida Y, Beauchamp R, Stemmer-Rachamimov A, Ramesh V, Gusella J, MacCollin M. Inactivation patterns of NF2 and DAL1 in sporadic meningiomas. Cancer Genetics and Cytogenetics, 162(2):135-139, 2005.
  3. Ahronowitz I, Xin W, Kiely R, Sims K, Maccollin M, Nunes FP. Mutational spectrum of the NF2 gene: a meta-analysis of 12 years of research and diagnostic laboratory findings. Hum Mutat. 28(1):1-12, 2007.
  4. Chang Z, Guo CL, Ahronowitz I, Stemmer-Rachamimov AO, MacCollin M, Nunes FP. A role for the p53 pathway in the pathology of meningiomas with NF2 loss. J Neurooncol. 91(3):265-70, 2009. (PMC2692701)
  5. Shen Y, Nunes F, Stemmer-Rachamimov A, James M, Mohapatra G, Plotkin S, Betensky RA, Engler DA, Roy J, Ramesh V, Gusella JF. Genomic profiling distinguishes familial multiple and sporadic multiple meningiomas. BMC Med Genomics. 2(1):42, 2009. (PMC2716362)
NCBI PubMed link NCBI PubMed Publications
E-mail address
Lab mailing address Simches Research Building
CPZN 3700
165 Cambridge Street
Boston, MA 02115
Clinical interests Familial Multiple Meningiomas Syndrome, Neurofibromatosis
Clinical address Pappas Center for Neuro Oncology
55 Fruit Street
Boston, MA 02114

Clinical website address

Neurofibromatosis Clinic


Updated 05/16/2011

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