blood vessels in eye tissue

Neuro-ophthalmology Service

The Neuro-ophthalmology Service at Massachusetts General Hospital provides expert evaluation, diagnosis and treatment for patients who have vision problems with a neurologic basis.
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Neuro-ophthalmology Service: 617-726-8639


Neuro-ophthalmology Doctors

Multiple Sclerosis Doctors

What to Expect

To make an appointment with our service, please call 617-724-5788. A referral is required from your ophthalmologist, neurologist or primary care physician.

Our physicians offer attentive, personalized care. During your first visit, we perform a detailed eye examination and conduct a variety of tests to help us pinpoint the exact nature of your problem.

When appropriate, we refer you to other Mass General specialties for further testing, such as the Neuroradiology Division. Our relationship with the nearby Massachusetts Eye and Ear Infirmary gives us access to many other advanced diagnostic tests, including optical coherence tomography, optic nerve imaging, fundus tomography and much more.

Making an accurate diagnosis is critical in identifying any risk of permanent visual loss or life-threatening disorders, or ruling out more serious conditions. Once our ophthalmologists have arrived at a diagnosis, we invite you back to discuss your individualized treatment plan.

Determining a Treatment OptionOur in-depth knowledge of these conditions and their natural progression allows us to determine the best course of treatment for each patient. Treatment options vary widely depending on your particular situation, from observation to medication or, when necessary, surgery.

As part of a world-class medical institution, we have access to the latest nonsurgical and surgical techniques. For some patients—e.g. those with multiple sclerosis (MS) or a pituitary tumor —we handle ongoing treatment within our service. For others, we make referrals to other specialists within the hospital, such as neuroendocrinologists or neurosurgeons, who have the precise knowledge necessary to treat his or her condition.

Expertise in Managing Rare ConditionsWith extensive training in both neurology and ophthalmology, our physicians have specialized expertise in diagnosing and treating the many disorders affecting both neurologic pathways and the visual system, from more common conditions such as MS and pituitary tumors to rare neuro-ophthalmic conditions.

In fact, our service is well-known for handling rare neuro-ophthalmic conditions. Many patients are referred to our program because their optometrist and/or general ophthalmologist could not diagnose their visual problem. Our ophthalmologists are trained to recognize rare diseases, which helps prevent unnecessary testing—and give patients peace of mind earlier in the process.


Updated 7/5/12

About this Program

Neuro-ophthalmology Doctors

Multiple Sclerosis Doctors

Much of the brain's capacity is dedicated to visual function and eye movements. As a result, many types of neurologic diseases can affect vision in some way. Our service often sees patients who are experiencing symptoms such as:

  • Optic nerve problems
  • Visual field loss
  • Unexplained visual loss
  • Transient visual loss
  • Visual disturbances
  • Double vision
  • Abnormal eye movements
  • Unequal pupil size
  • Eyelid abnormalities

These and other symptoms are frequently caused by one of the following conditions:

  • Multiple sclerosis (MS): A chronic disease of the central nervous system, MS and neuro-visual complications of MS can lead to visual problems
  • Myasthenia gravis: With this complex autoimmune disorder, antibodies destroy neuromuscular connections to cause problems with the nerves that communicate with muscles
  • Pituitary tumors: These usually benign brain tumors press against the optic nerves, causing vision problems
  • Migraine: Visual disturbances are one of the common symptoms of migraine
  • Stroke: Dimness or loss of vision in one or both eyes may be attributable to stroke
  • Autoimmune disease: These diseases can often affect the optic nerve and/or parts of the brain that serve vision

Pediatric & Adult Care

For pediatric patients, our service's primary role is consultation. Working in conjunction with pediatric neurologists at MassGeneral Hospital for Children, the Massachusetts Eye and Ear Infirmary or Children's Hospital Boston, we can often help identify even the rarest of neuro-ophthalmic conditions. Following the diagnosis, we typically refer children to one of these entities for treatment.

For adult patients, we offer both diagnostic and treatment services. Our physicians evaluate patients from neurologic, ophthalmic and general medical perspectives to diagnose the origin of visual problems. We can also clarify retinal problems, which may sometimes accompany and/or mimic neurologic symptoms.

Education & Research a Priority

Shirley Wray, MD, PhD, a distinguished member of our program, is now exclusively engaged in research after a long clinical career. The neuro-ophthalmology research library that she built over a 30-year period assists our staff in making diagnoses and is valued by other physicians and scientists around the world.

Ophthalmology-Related Links

The list of resources below are outside of the Massachusetts General Hospital.


Updated 7/5/12

Conditions & Diseases

  • Ataxia

    Ataxia causes a failure of muscle control in the arms and legs which may result in a lack of balance, coordination and possibly a disturbance in gait.

  • Ataxia Telangiectasia (A-T)

    Ataxia telangiectasia is a rare childhood disease that affects the nervous system and some other body systems.

  • Headache

    A headache is pain or discomfort in the head or face area.

  • Myasthenia Gravis

    Myasthenia gravis (MG) is a complex, autoimmune disorder in which antibodies destroy neuromuscular connections. This causes problems with the voluntary muscles of the body, especially the eyes, mouth, throat, and limbs.

  • Stroke

    Stroke, also called brain attack, occurs when blood flow to the brain is disrupted.

  • Vascular Headaches and Migraines

    This throbbing type of headache is distinguished by the fact that symptoms other than pain occur with the headache.

Clinical Trials


  • Partners Neurology Residents at Mass General

    Partners Neurology Residency

    Neurology residents, program graduates, faculty members, and the education director talk about training at Mass General Hospital and Brigham and Women’s Hospital.


Contact Us

Neuro-Ophthalmology Service

Wang Ambulatory Care Center

15 Parkman Street8th Floor, Suite 835 Boston, MA 02114
  • Near Public Transit
  • Accessible
  • Phone: 617-724-5788
  • Fax: 617-726-6991

Mailing Address

Department of Neurology
Neuro-Ophthalmology Service
Mailcode: Wang ACC 8-835
Massachusetts General Hospital
55 Fruit Street
Boston, MA 02114
Clinical CoordinatorAmy Leary

Access Patient Gateway

Neuro-ophthalmology Service: 617-726-8639

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