Gene Therapy Produces Long-term Contraception in Female Domestic Cats
A single dose of a viral vector containing anti-Müllerian hormone, a naturally occurring hormone, prevented ovulation and conception in female cats for at least two years.
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Genetic variants may affect treatment response to commonly prescribed type 2 diabetes medication
In a study of individuals at risk for developing type 2 diabetes, researchers identified genetic variants linked with participants’ responses to two different blood sugar–lowering drugs.
All of Us Research Program Celebrates Five Years and Milestone Achievements with Release of Nearly 250K Whole Genome Sequences
Genomic dataset is the world’s largest, most diverse of its kind, integrated with other robust data
Alzheimer’s Disease Plasma Biomarker and Pathogenesis Contribute to Postoperative Delirium-like Behavior in Rodents
By employing Tau knockout mice, the investigators demonstrated that Tau-PT217 in the blood could traverse the blood brain barrier to enter the brain tissues of aged mice.
Remembering Henry Bowditch, MD, a Trailblazer for Equality at Mass General and Beyond
Henry Ingersoll Bowditch, MD, a longtime Mass General physician, abolitionist and public health pioneer, was no stranger to controversy.
Researchers Call for Changes to State Law Requiring Child Protective Services to Be Notified When Medications for Opioid Use Disorder Are Used During Pregnancy
A team of researchers led by Davida M. Schiff, MD, director of Perinatal and Family Based Substance Use Disorders Care at Massachusetts General Hospital, conducted a study to learn more about the impact of regulations on pregnant and postpartum individuals with OUD. Their findings were recently published in the Maternal and Child Health Journal.
grand-rounds-may-17-2023
grand-rounds-may-17-2023. grand-rounds-may-17-2023. How can we reduce the environmental impact of inhaled treatments whilst simultaneously improving the quality of care that we deliver? These are some key challenges facing physicians managing chronic
Sean M. Healey & AMG Center for ALS Announces First participant Dosed in Regimen G of the HEALEY ALS Platform Trial Evaluating DNL343 by Denali Therapeutics
DNL343 is a novel investigational ALS therapy that targets eIF2B, a central regulator of the integrated stress response (ISR).
Gut Microbiome Changes Linked to Precancerous Colon Polyps
Understanding the link between the gut microbiome and polyp growth opens the door to potential screenings and treatments.
Caroline's Story: A Long Labor of Love | Department of Obstetrics & Gynecology at Massachusetts General Hospital
During the summer of 2021, Caroline and her husband, Ryan, found out they were expecting a daughter, due on St. Patrick’s Day.
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