Department of Medicine
COVID-19 Grand Rounds Series
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Medical Grand Rounds
Under the auspices of the department's Medical Grand Rounds, these timely and informative talks bring together the leading medical experts working to address this new global challenge.
Previous Grand Rounds
March 4, 2021, 8:00 am - 9:00 am
International Responses to COVID-19s
This virtual event's scheduled speakers included Louise Ivers, MD, MPH, interim chief of the Division of Infectious Diseases at Massachusetts General Hospital; Inobert Pierre, MD, St. Boniface Hospital director general, Health Equity International, Haiti; Todd M. Pollack, MD, FIDSA, country director, The Partnership for Health Advancement in Vietnam (HAIVN), Beth Israel Deaconess Medical Center; Sara Suliman, MPH, PhD, director of the MGB Center for COVID-19 Innovation (MGBCCI) Diagnostics Accelerator Lab and instructor of Medicine at Brigham and Women’s Hospital; and Gama Petulo Bandawe, PhD, senior lecturer and head of department, Department of Biological Sciences, Academy of Medical Sciences, Malawi University of Science and Technology.
February 4, 2021, 8:00 am - 9:00 am
Not Throwing Away Our Shot: Scaling Up COVID-19 Vaccination Efforts in the United States
This virtual event's scheduled speakers included Massachusetts General Hospital's Joshua P. Metlay, MD, PhD, chief of the Division of General Internal Medicine, and Bisola Ojikutu, MD, MPH, of the Division of Infectious Diseases, Brigham and Women’s Hospital and Mass General and Division of Global Health Equity at Brigham and Women’s Hospital; Dhruv S. Kazi, MD, MSc, MS, associate director, Richard A. and Susan F. Smith Center for Outcomes Research in Cardiology and director, Cardiac Critical Care Unit at Beth Israel Deaconess Medical Center; and Ai-Ris Y. Collier, MD, Division of Maternal Fetal Medicine at Beth Israel Deaconess Medical Center.
January 7, 2021, 8:00 am - 9:00 am
COVID-19 Treatment Update for ‘21
This virtual event's scheduled speakers included Arthur Y. Kim, MD, Division of Infectious Diseases, Massachusetts General Hospital; Ari Moskowitz, MD, Pulmonary and Critical Care Medicine, Beth Israel Deaconess Medical Center; Kathryn Stephenson, MD, MPH, Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Ragon Institute of MGH, MIT and Harvard; and Francisco M. Marty, MD, Division of Infectious Diseases, Brigham and Women’s Hospital, Dana-Farber Cancer Institute.
December 3, 2020
COVID-19 Transmission: A State of the State, Our Schools and the NBA
This virtual event's scheduled speakers included Sandra B. Nelson, MD, Division of Infectious Diseases, Massachusetts General Hospital; Catherine M. Brown, DVM, MSc, MPH, state epidemiologist, state public health veterinarian, Massachusetts Department of Public Health; and David Weiss, senior vice president, player matters, National Basketball Association.
November 5, 2020
The Quest for a COVID-19 Vaccine
This virtual event's scheduled speakers included Bruce Walker, MD, Ragon Institute of Mass General, MIT and Harvard; Dan Barouch, MD, PhD, Beth Israel Deaconess Medical Center and Ragon Institute of Mass General; Andrea Carfi, PhD, Moderna; Jonathan Abraham, MD, PhD, Brigham and Women’s Hospital; and Galit Alter, PhD, Ragon Institute of Mass General, MIT and Harvard.
October 15, 2020
COVID-19: Safe Voting During the 2020 U.S. Elections
This Harvard Medical Grand Rounds examined voting safety, including various challenges, innovations and the role of health care professionals. Charles Stewart III, Kenan Sahin Distinguished Professor of Political Science, Massachusetts Institute of Technology, was the featured speaker. Panelists included Sejal Hathi, MD, MBA and Radhika Jain, MD, both of Massachusetts General Hospital; Audrey Li, MD, and Debanjan Pain, MD, both of Beth Israel Deaconess Medical Center; and Jonathan Kusner, Harvard Medical School.
September 10, 2020
COVID-19: Public Health and Scientific Challenges
In a virtual Medical Grand Rounds co-hosted by Massachusetts General Hospital, Brigham and Women’s Hospital and Beth Israel Deaconess Medical Center on Sept. 10, 2020, Anthony S. Fauci, MD, director of the National Institute of Allergy and Infectious Diseases (NIAID), spoke to the Boston medical community about COVID-19 public health and scientific challenges. The session was moderated by Katrina Armstong, MD, physician-in-chief in the Department of Medicine at Mass General. Panelists included Rochelle Walensky, MD, MPH, chief, Division of Infectious Diseases at Mass General, Sharon B. Wright, MD, MPH, senior medical director, Infection Control/Hospital Epidemiology at Beth Israel Deaconess Medical Center, and Michael Klompas, MD, MPH, hospital epidemiologist at Brigham and Women’s Hospital.
July 16, 2020
COVID-19: Patient Recovery and Rehab
This Department of Medicine Grand Rounds focused on case studies and data that can inform approaches to COVID-19 patient recovery and rehab. Featured speakers included Jason H. Maley, MD, research fellow, and George A. Alba, MD, physician in the Department of Medicine, of Massachusetts General Hospital; Ginger Polich, MD, instructor of physical medicine and rehabilitation at Spaulding Rehabilitation Hospital; Zahir Kanjee, MD, MPH, Anica C. Law, MD, and Margaret Hayes, MD, of Beth Israel Deaconess Medical Center; and Kathleen J. Haley, MD, of Brigham and Women’s Hospital.
July 9, 2020
COVID-19 and Health Equity: A Focus on Health System Solutions to Magnified Inequities
This Harvard Medical Grand Rounds examined ways in which the COVID-19 pandemic has revealed and exacerbated global health inequities. Featured speakers included Joseph Betancourt, MD, MPH, and Aisha James, MD, MS, of Massachusetts General Hospital; Beth Riviello, MD, MPH, and Rose L. Molina, MD, MPH, of Beth Israel Deaconess Medical Center; and Valerie Stone, MD, MPH, and Bisola Ojikutu, MD, MPH, of Brigham and Women’s Hospital.
June 18, 2020
A 66-Year-Old Liver Transplant Recipient with COVID-19
This Combined Medical-Surgical Grand Rounds lecture reviewed the case of a 66-year-old liver transplant recipient with COVID-19. The panel featured Jay A. Fishman, MD, Matthew B. Roberts, MB, BS, and Eric W. Zhang, MD, of Massachusetts General Hospital; Deepali Kumar, MD, of the University of Toronto, Canada; Hans H. Hirsch, MD, MSc, of the University Hospital Basel, Switzerland; and Umberto Maggiore, MD, of the University of Parma, Italy.
June 11, 2020
June 11th Medical Grand Rounds
The 14th lecture in the Medical Grand Rounds' COVID-19 series focused on the role of platelets and prescriptions in COVID-19. The panel included Nancy Haff, MD, primary care physician, Nino Mihatov, MD, cardiology fellow at Mass General, and other members of the Boston medical community.
June 4, 2020
Vaccine Development for COVID-19: A Status Update on the Challenges and Prospects for Success
The 13th lecture in the Medical Grand Rounds' COVID-19 series provided an update on efforts to develop a safe, scalable vaccine for COVID-19. The panel featured Mason W. Freeman, MD, of Massachusetts General Hospital, Daniel Barouch, MD, PhD, of Beth Israel Deaconess Medical Center, and Lindsey Robert Baden, MD, of Brigham and Women’s Hospital.
May 28, 2020
Impact of COVID-19 among Older Persons
The 12th lecture in the Medical Grand Rounds' COVID-19 series focused on the impact of COVID-19 in older populations. The panel included Christine Seel Ritchie, MD, MSPH, Sharon Levine, MD, and Jehan Alladina, MD, of Massachusetts General Hospital; Susan L. Mitchell, MD, MPH, and Sharon K. Inouye, MD, MPH, of Beth Israel Deaconess Medical Center; and Shalender Basin, MB, BS, Laura Nelson Frain, MD, MPH, and Shoshana Streiter, MD, of Brigham and Women’s Hospital.
May 21, 2020
COVID-19 and Acute Kidney Injury
The eleventh lecture in the Medical Grand Rounds' COVID-19 series featured Eugene Rhee, MD, Meghan Sise, MD, and Win Williams, MD, of the Nephrology Division at Massachusetts General Hospital; Peter Czarnecki, MD, David Leaf, MD, MMSc, and Danielle Saly, MD, of Brigham and Women’s Hospital; and David Friedman, MD, Samir Parikh, MD, and Martin Pollak, MD, of Beth Israel Deaconess Medical Center.
May 14, 2020
Cardiac Manifestations of COVID-19
The tenth lecture in the Medical Grand Rounds' COVID-19 series featured Anthony Rosenzweig, MD, Jason Wasfy, MD, MPhil, and Judy Hung, MD, of Massachusetts General Hospital; Dhruv Kazi, MD, MSc, MS, Lila Martin, MD, and Duane Pinto, MD of Beth Israel Deaconess Medical Center; and David Morrow, MD, MPH, Mandeep Mehra, MD, MSc, and Erin Bohula May, MD, DPhil, of Brigham and Women’s Hospital.
Speakers:
00:00 - Introductions and Overview
02:18 - Jason Wasfy, MD, MPhil - Cardiac Outcomes During the COVID-19 Pandemic
09:54 - Mandeep R. Mehra, MD, MSc - Pathobiology of Cardiac Injury in COVID-19
24:05 - Lila Martin, MD, MPH - Case Presentation
26:30 - Erin Bohula May, MD, DPhil - Differential Diagnosis
32:10 - Judy Hung, MD - The Role of Cardiac Imaging in Management of COVID-19 Patients
36:43 - Duane Pinto, MD - Catheterization Laboratory Considerations
44:37 - Dhruv S. Kazi, MD, MSc, MS - Clinical, Ethical and Health Economic Considerations
54:37 - Questions and Answers
May 7, 2020
Unraveling the Mystery of Clotting in COVID-19
Featured speakers in the ninth lecture in the Medical Grand Rounds' COVID-19 series included Pavan Bendapudi, MD, and Hanny Al-Samkari, MD, of Massachusetts General Hospital; Jason Freed, MD, Jeffrey Zwicker, MD, and Robert Flaumenhaft, MD, PhD, of Beth Israel Deaconess Medical Center; and Jean Marie Connors, MD, of Brigham and Women's Hospital.
Speakers:
00:00 - Introductions
01:24 - Jason Freed, MD - Case Presentation: 55-year-old Woman with Four Days of Cough and Low Grade Fever
03:45 - Jeff Zwicker, MD - COVID-19 Coagulopathy: The Unfolding Story
12:52 - Robert Flaumenhaft, MD, PhD - Endothelial Mechanisms of COVID-related Thrombosis
25:12 - Pavan Bendapudi, MD - Hemorrhage and Hyperfibrinolysis in COVID-19 Infection
35:10 - Hanny Al-Samkari, MD - COVID, Coagulation and Inflammation
42:37 - Jean M. Connors, MD - Anticoagulation in COVID-19 Patients: A Clinician's Perspective
1:01:02 - Questions and Answers
April 30, 2020
How Diagnostic Tests for COVID-19 Got Us into, and Will Lead Us Out of, the Pandemic
Featured speakers in the eighth lecture in the Medical Grand Rounds' COVID-19 series included Galit Alter, PhD, and Wilfredo García Beltrán, MD, PhD, of the Ragon Institute of MGH, MIT and Harvard; Marc Lipsitch, DPhil, of the Harvard T.H. Chan School of Public Health; Christopher Rowley, MD, MPH, and Bess Flashner, MD, of Beth Israel Deaconess Medical Center; and Sanjat Kanjilal, MD, MPH, of Brigham and Women’s Hospital.
Speakers:
00:00 - Katrina Armstrong, MD - Introduction
02:32 - Bess Flashner, MD - Case Presentations: Common Challenges in Treating and Testing COVID-19 Patients
09:10 - Christopher Rowley, MD, MPH - Timeline of the COVID-19 Pandemic in the U.S.
21:52 - Sanjat Kanjilal, MD, MPH - Molecular Diagnostics for SARS-CoV-2
32:20 - Galit Alter, PhD - The Wild-West of Antibody Testing...and the Basics
37:44 - Wilfredo F. García Beltrán, MD, PhD - COVID-19 Serological Testing at Mass General
49:28 - Marc Lipsitch, DPhil - Serology for Epidemiology and Public Health
01:02:57 - Questions and Answers
April 23, 2020
A 66-year-old Man with Homelessness, with Cough and Rhinorrhea: Response to COVID-19 Among Boston’s Homeless Population
The seventh lecture in the Medical Grand Rounds' COVID-19 series focused on a case study which shed light on the challenges associated with preventing and treating COVID-19 among Boston's homeless population.
Featured speakers included David Munson, MD, instructor in medicine at Harvard Medical School and medical director of Respite Programs at Boston Health Care for the Homeless; Jessie Gaeta, MD, and Denise De Las Nueces, MD, MPH, of Boston Health Care for the Homeless and Boston University School of Medicine; and Kate Walsh, MPH, and Joshua A. Barocas, MD, MPH, of Boston Medical Center.
Speakers:
00:29 - David Dudzinksi, MD - Introduction and Overview
01:32 - Denise De Las Nueces, MD, MPH - Case History
05:53 - David Munson, MD - Respite Management
11:46 - Jessie M. Gaeta, MD - Boston Health Care for the Homeless Program Response
34:33 - Joshua A. Barocas, MD - Approach to Infection Control in an Evolving Pandemic
47:56 - Kate Walsh, MPH - Hospital Response to Persons Experiencing Homelessness During the COVID-19 Pandemic
58:25 - Jessie M. Gaeta, MD - Summary
1:01:58 - Questions and Answers
April 16, 2020
Publishing in a Pandemic: How Medical Journals are Responding to COVID-19
The sixth lecture in the Medical Grand Rounds' COVID-19 series focused on the role of medical journals in the development of new therapies and approaches to patient care during the COVID-19 pandemic.
Featured speakers included:
- Chana A. Sacks, MD, internist at Mass General and images editor at the New England Journal of Medicine
- Martin Hirsch, MD, senior physician in the Infectious Disease Service at Mass General and editor-in-chief of the Journal of Infectious Diseases
- Mary Beth Hamel, MD, MPH, internist at Beth Israel Deaconess Medical Center and executive deputy editor of the New England Journal of Medicine
- Paul Sax, MD, clinical director of the HIV Program and Division of Infectious Diseases at Brigham and Women’s Hospital
- Howard Bauchner, MD, professor of pediatrics and community health sciences at the Boston University School of Medicine and editor-in-chief of Journal of the American Medical Association
Speakers:
00:26 - Eileen Reynolds, MD - Introduction
01:00 - Chana A. Sacks, MD - Overview
02:41 - Howard Bauchner, MD - Report from JAMA
08:13 - Mary Beth Hamel, MD, MPH - Report from the NEJM
13:15 - Martin Hirsch, MD - Report from the Journal of Infectious Diseases
18:53 - Chana A. Sacks, MD - Do Publishing Standards Change in a Pandemic?
31:44 - Martin Hirsch, MD - Pandemics Throughout History
41:56 - Paul Sax, MD - Reflections on Publishing in a Pandemic
45:30 - Closing Thoughts
51:05 - Questions and Answers
April 9, 2020
Advancing New Therapies for COVID-19: Anti-viral, Immunomodulation and Beyond
Featured speakers in the fifth lecture of the Medical Grand Rounds' COVID-19 series included Keith Flaherty, MD, Michael Mansour, MD, PhD, and Kathryn Hibbert, MD, of Massachusetts General Hospital; Kathryn Stephenson, MD, MPH, and Barbra Blair, MD, from Beth Israel Deaconess Medical Center; Richard Kaufman, MD, from Brigham and Women’s Hospital; and Scott Gottlieb, MD, former commissioner of the Food and Drug Administration and current fellow at the American Enterprise Institute.
Speakers:
00:15 - Katrina Armstrong, MD - Overview
01:55 - Keith Flaherty, MD - COVID-19 Clinical Trial Strategy: Signal Seeking vs. Optimal Deployment
06:09 - Kathryn E. Stephenson, MD, MPH - Antiviral Therapies for COVID-19
13:43 - Richard Kaufman, MD - COVID-19 Convalescent Plasma
25:22 - Michael K. Mansour, MD, PhD - COVID Immunomodulation Group (CIG)
42:20 - Barbra M. Blair, MD - Hydroxychloroquine (HCQ) & COVID-19
50:29 - Kathryn Hibbert, MD - COVID-19 ARDS Trials
59:13 - Scott Gottlieb, MD - The Role of Regulatory Authorities in Accelerating Therapeutic Advances
1:19:25 - Questions and Answers
April 2, 2020
Palliative Care in a Pandemic
The fourth lecture in the Medical Grand Rounds’ COVID-19 series featured Palliative Care experts and the growing role of that discipline in the response to the pandemic.
Speakers included Vicki Jackson, MD, Emily Rubin, MD, Juliet Jacobsen, MD, from Mass General; Mary Buss, MD, PhD, and the Rev. Kathleen Rimer from BIDMC; and Isaac Chua, MD, from Dana-Farber and Brigham & Women's Hospital.
Speakers:
00:46 - Vicki Jackson, MD - Overview
06:36 - Juliet Jacobsen, MD - Generalist Palliative Care and Communication
15:29 - Isaac Chua, MD, MPH - Responding to Emotion with Telehealth
21:55 - Emily Rubin, MD - Ethical Principles in the Allocation of Scarce Resources During a Public Health Emergency
30:49 - Mary K. Buss, MD, MPH - Addressing Moral Distress
45:50 - Rev. Kathleen Rimer - Maintaining Humanity and Compassion
57:38 - Questions and Answers
March 26, 2020
Pathogenesis and Management of Respiratory Failure in COVID-19: What We Know So Far
The third lecture in the Medical Grand Rounds’ COVID-19 series focused on respiratory failure in COVID-19. Speakers included Benjamin Medoff, MD, Jehan Alladina, MD, Jayaraj Rajagopal, MD, Jason Griffith, MD, PhD, and Taylor Thompson, MD, of Mass General; Rebecca Baron, MD, of Brigham and Women’s Hospital; and Ari Moskowitz, MD, Robert Hallowell, MD, and Richard Schwartzstein, MD, of Beth Israel Deaconess Medical Center.
Speakers:
02:56 - Jehan Alladina, MD - Case Presentation
07:41 - Rebecca Baron, MD - Mechanisms Underlying ARDS (With a Focus on COVID-19)
18:45 - Ari Moskowitz, MD - Basics of Management
34:00 - Jason Griffith, MD, PhD - Aberrant Immune Responses to Respiratory Viral Infection: Lessons from Influenza
41:45 - Rob Hallowell, MD - Experimental Therapies
52:22 - Jayaraj Rajagopal, MD - The Lung Cell Atlas: COVID-19
57:18 - Taylor Thompson, MD - Hyperinflammation and Use of Steroids in ARDS
59:33 - Richard Schwartzstein, MD - Cognitive Biases in Recommendations for Treatment and Parallels to the HIV/AIDS Epidemic
1:02:42 - Questions and Answers
March 19, 2020
March 12, 2020
Additional Resources
Responding to COVID-19
Mass General has activated its Hospital Incident Command System (HICS) in response to the ongoing Coronavirus (COVID-19) pandemic. Please find the latest news and information here.