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My primary focus has been on the treatment of fibroids in primarily reproductive-aged women, uterine anomalies, and other anatomic causes of infertility that can be addressed surgically. I also maintain a very robust infertility practice where I help patients start their families.
Obstetrics & Gynecology
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I completed my undergraduate training at the University of Texas at El Paso, majoring in Biology with a minor in Chemistry. I matriculated to the University of Texas Medical Branch in Galveston for medical school, and in 1988, also participated in a summer internhsip at the NIH working with the development of a rapid diagnostic skin test for people infected with Strongyloides stercoralis, before starting my clinical years. I completed my internship and residency in Obstetrics and Gynecology at LBJ Hospital and the University of Texas Health Sciences Center in Houston. I finally left Texas and ventured to the northeast, where I did my fellowship in Reproductive Endocrinology and Infertility at New England Medical Center (NEMC) / Tufts Medical School. I stayed on staff at NEMC for 6 years before moving to Massachusetts General Hospital.
Over my career, I have focused on the surgical aspect of infertility and reproduction. This includes endometriosis, fibroids, surgical repair of uterine anomalies and scar tissue, and repair of damaged fallopian tubes. I also co-direct the Mass General Integrated Fibroid Program. I have a strong interest in fertility treatment outcomes, reproductive surgery outcomes, environmental factors and reproduction, diversity in reproductive health care treatments.
View my most recent research
Fibroids - my primary interest is in treatment outcomes, efficiency modeling, and shared health decision making.
Souter I, Baltagi L, Toth T, Petrozza JC. Prevalence of hyperprolactinemia and abnormal magnetic resonance imaging in a population with infertility. Fertil Steril, 2010; 94(3):1159.
Karimov CB, Cronister A, Srouji S, Petrozza JC, Racowsky C, Ginsburg E, Santolaya J, Welt C, Increased Prevalence of the FMR1 Premutation in Infertile Menstruating Women with Primary Ovarian Dysfunction, accepted Human Reprod., 2011.
Souter I, Baltagi L, Kuleta, D, Meeker J, Petrozza JC. Women, weight, and fertility: The effect of body mass index on the outcome of superovulation/intrauterine insemination cycles. Fertil Steril. 2011 ;95(3):1042
Petrozza JC, Mayer-Rokitansky-Kuster-Hauser Syndrome and associated malformations: are they as common as we think? Fertil Steril 2016 epub.
Dimitriadis I, Batsis M, Petrozza JC, Souter I. Racial disparities in fertility care: an analysis of 4537 intrauterine insemination cycles. J Racial Ethn Health Disparities. 2016 Mar 16.
The Fibroid Program at Massachusetts General Hospital offers patients access to a full range of multidisciplinary options to treat uterine fibroids.
Dr. John Petrozza, chief of Reproductive Medicine and IVF at Massachusetts General Hospital and director the MGH Fertility Center, offers advice to men who want to better understand infertility.
Painful fibroids kept opera singer Denyce Graves from conceiving. With the help and expertise of John Petrozza, MD, director of the Division of Reproductive Medicine and In Vitro Fertilization and co-director of the Mass General Fibroid Program, she gave birth to a baby girl. "He was the most hopeful of all the doctors I'd seen," she said.
Melissa Leverett King is an active mom and teacher who lived with limiting discomfort and pain until she got treated for fibroids with UFE (uterine fibroid embolization).
John Petrozza, MD, chief of the Reproductive Endocrine and Infertility Service at the Massachusetts General Hospital Fertility Center, discusses how patients benefits from having a fertility center within a hospital.
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