Here, we answer questions about COVID-19 that pertain to pregnant patients and the COVID-19 booster shot. After reviewing this page, we encourage you to visit the Mass General Brigham COVID-19 website for more complete information about ways you can protect yourself and your loved ones from the novel coronavirus.

Mass General Brigham COVID-19 Info

Q: Why are COVID-19 vaccine boosters being recommended for certain high-risk individuals?

A: The FDA reviewed data that demonstrated levels of immunity decrease slightly over time and after more than six months following the initial Pfizer or Moderna vaccine series and after more than two months following the initial Johnson & Johnson vaccine. Studies have shown a small increase in breakthrough COVID-19 cases compared to individuals who were vaccinated more recently. While so far these breakthrough cases in reproductive age individuals have not been associated with more severe illness, hospitalizations or deaths, the FDA and the CDC believe that certain high-risk populations could benefit from additional protection.

Q: Is pregnancy an indication to get a COVID-19 booster?

A: Yes. All pregnant people, ages 18 and older, who received any of the COVID-19 vaccines greater than six months ago for Pfizer or Moderna and greater than two months ago for Johnson & Johnson are recommended to get a vaccine booster. 

Q: Should my booster be the same vaccine I got before or can I "mix and match"?

A: Individuals may choose which vaccine they receive as a booster dose. Some people may want to get the vaccine they originally received, and others may prefer to get a different booster. The CDC's recommendations now allow for this type of "mix and match" dosing for booster shots.

There have been very rare reports of a type of blood clot called cerebral venous sinus thrombosis among patients that have received the Johnson & Johnson vaccine. Though very rare, the risk of certain blood clots appears to be highest in women aged 18–49. At this time, although the chance of blood clots occurring as a result of this vaccine is very low, the FDA and CDC have stated that the mRNA vaccines are the preferred vaccine for original vaccination as well as the booster.

Q: Can I get a flu shot at the same time as my COVID-19 booster?

A: Yes, you can get the COVID-19 vaccine booster any time even if you recently received a flu vaccine. You can even get them both on the same day.

Still have questions?

Additional References and Resources


This content was prepared by Ilona Goldfarb, MD, for the Department of Obstetrics and Gynecology.
Date originally published: 10/7/2021
Date updated: 10/27/2021