Histocompatibility Laboratory

The Histocompatibility Laboratory is ASHI certified and performs the testing required for bone marrow and solid organ transplantation services at MGH.

Tests include both serologic and DNA-based HLA typing; determination of HLA antibody frequency (PRA) and specificity using cytotoxicity, ELISA and Luminex assays; lymphocyte crossmatching and microsatellite assays to monitor for chimerism and/or bone marrow engraftment.

The lab also does HLA typing and antibody testing required by the MGH Blood Transfusion Service and Blood Donor Center. Total HLA lab test volume is approximately 11,000 tests per year.

Laboratory Hours
8:30 am to 5:00 pm Monday through Friday
(an on-call technologist is available at all other times)


Susan L. Saidman, PhD, Laboratory Director

Clinical / Contact Information

MGH Laboratory Handbook: Histocompatibility Laboratory













Updated 4/8/2011


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