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The Center for Addiction Medicine (CAM) is one of the major clinical research programs of the Department of Psychiatry at Massachusetts General Hospital. CAM provides treatment, research and training opportunities in a multidisciplinary, outpatient setting.
Learn more about CAM:
We offer outpatient treatment through several programs:
Addiction Recovery Management Service (ARMS)ARMS provides rapid access to addiction information and support services for families, combined with outreach and care management for youth ages 14-26 suffering from substance-related problems.
West End Clinic for Addiction TreatmentThe West End Clinic is an outpatient facility for those with alcohol and drug addictions, co-occurring mental health disorders and other types of addictive behaviors.
Recovery Research Institute
The Recovery Research Institute is a nonprofit research institute of Massachusetts General Hospital, an affiliate of Harvard Medical School, dedicated to the advancement of addiction treatment and recovery science. Founded in 2012 by Dr. John F. Kelly, the Recovery Research Institute is a team of innovative scientists working through research, education and outreach to enhance recovery through science, conducting and disseminating the most up-to-date research findings for individuals, families, healthcare professionals and policymakers alike.
CAM Research ProgramCAM is involved in various collaborative efforts with clinics within Massachusetts General Hospital, Harvard Medical School, MIT and Tufts University, as well as community agencies in the Boston area.
Professional education at CAM
By integrating Mass General’s exceptional clinical, research and teaching capabilities, CAM has expanded the boundaries of addiction research. The clinical environment at CAM is ideal for clinical research in substance use disorders.
The clinical research program at CAM was developed specifically to support clinical investigators through educational support, grant review, statistical consultation, recruitment support, peer support and direct project management support for clinical investigations.
William Cox Family Professor of Psychiatry in Addiction Medicine, Harvard Medical SchoolFounding Director and Director for Academics and Research, Center for Addiction MedicineFaculty, Mass General Schizophrenia Clinical and Research ProgramPublications
Dr. Evins completed her residency in adult psychiatry at the Massachusetts Mental Health Center and Longwood Psychiatry Residency Training Program and fellowships in molecular biology at the Mailman Research Center of McLean Hospital and in clinical research at the Schizophrenia Program. She completed a Masters in Public Health with a concentration in Clinical Effectiveness at the Harvard School of Public Health in 2005. She has been an active member of the Schizophrenia and Depression Clinical and Research Program since 1995. She founded the CAM in 2005.
Dr. Evins' research interests include pharmacotherapy for nicotine dependence, co-occurring psychiatric and substance use disorders, negative symptoms and cognitive dysfunction in schizophrenia, and impact of cannabis on cognition and psychiatric illness. Dr Evins has authored articles, book chapters, and reviews concerning topics in this field.
Dr. Evins has twice been the recipient of the National Alliance for Research on Schizophrenia and Affective Disorders Young Investigator Award, and has been awarded the New Clinical Drug Evaluation Unit Award for Young Investigators sponsored by the National Institute of Mental Health, the Massachusetts Department of Public Health Young Investigator Award and three career development awards from NIDA. She is currently supported by six major grants from NIDA, NIMH, and NHLBI to test novel therapies for nicotine dependence in the general population and in those with co-occurring psychiatric disorders.
Elizabeth R. Spallin Associate Professor of Psychiatry in Addiction Medicine, Harvard Medical School; Founder & Director of the Recovery Research InstitutePublications Books
Dr. John F. Kelly is the Elizabeth R. Spallin associate professor of psychiatry in addiction medicine at Harvard Medical School – the first endowed professor in addiction medicine at Harvard. He is the founder and director of the Recovery Research Institute at Massa General, the program director of the Addiction Recovery Management Service (ARMS) and the associate director of the Center for Addiction Medicine. Dr. Kelly is a past president of the American Psychological Association (APA) Society of Addiction Psychology, is a fellow of the APA, and a diplomate of the American Board of Professional Psychology (ABPP). He has served as a consultant to U.S. federal agencies such as the White House Office of National Drug Control Policy (ONDCP), the Substance Abuse and Mental Health Services Administration (SAMHSA), and the national Institutes of Health (NIH); to national non-Federal treatment institutions, such as the Hazelden Betty Ford Foundation and Caron Foundation, and to foreign governments.
CAM Program Director, Assistant in Research Psychiatry MGH, Instructor in Psychiatry Harvard Medical SchoolPublications
Dr. Pachas received her medical degree from the San Martin de Porres University and her health services management and public health training from the National University Mayor de San Marcos in Lima, Peru. Her research interests are the development of evidence-based novel treatment for smoking cessation and relapse prevention in people with and without serious mental illness. Dr. Pachas is the recipient of the NIMH-NCDEU Young Investigator Award, the MGH Clinical Research Day Departmental Award in Psychiatry, the NIH-NIDA Interdisciplinary Research Training Institute on Hispanic Drug Abuse Fellowship, the American Society of Clinical Psychopharmacology Fellowship and the Society for Research on Nicotine and TobaccoHealth Disparitiesfellowship. Dr. Pachas is involved in the clinical component of complex Phase II trials of novel pharmacologic agents for smoking cessation and relapse prevention.
Associate Director, Recovery Research Institute
Brandon Bergman, PhD, is the associate director and a research scientist at the Recovery Research Institute (RRI). He writes and helps oversee content for a range of institute materials, including the website and Recovery Bulletin. Dr. Bergman has specialized knowledge in recovery processes and outcomes during the developmental stage of emerging adulthood (18-29 years), community-based resources to extend and enhance addiction treatment outcomes, as well as recovery-specific social network sites and other forms of digital recovery management. His work on the application of social network site technology to elucidating and enhancing emerging adult treatment and recovery is supported by a career development grant (K23) from the National Institute on Alcohol Abuse and Alcoholism. Dr. Bergman is a licensed psychologist, having completed his PhD in Clinical Psychology at Nova Southeastern University, and his psychology internship and addiction psychology postdoctoral fellowship at the Massachusetts General Hospital and Harvard Medical School.
Director Psychology Services at CAM & the Schizophrenia Program, Co-founder First Episode and Early Psychosis Program, Assistant in Psychiatry, Assistant Professor of Psychology, Harvard Medical SchoolPublications
Dr. Cather earned her undergraduate degree in biopsychology at Hamilton College and her doctorate in clinical psychology from Rutgers University, where she received specialized training in cognitive behavioral therapy (CBT) and behavioral medicine. She completed an internship at the University of Medicine and Dentistry of New Jersey (formerly Rutgers) and joined the Schizophrenia Clinical and Research Program in 1999 as a fellow. She has extensive experience as a clinician-researcher with first episode/early psychosis as well as with chronic schizophrenia and she has developed an international reputation as one of the few practitioners in the US skilled in CBT in schizophrenia.
Dr. Cather has worked with Dr. Evins since 1999 to investigate the efficacy of combined behavioral and pharmacological treatments for nicotine dependence in smokers with severe mental illness. She has manualized treatments for enhancing motivation to quit smoking, smoking cessation and relapse prevention for this population of smokers.
Dr. David Eddie is a research scientist at the Recovery Research Institute and Center for Addiction Medicine, a clinical psychologist in the Department of Psychiatry, and an instructor at Harvard Medical School. His current research, supported by NIAAA and internal awards from Mass General, Harvard Medical School, and Harvard University is seeking to better understand affective and psychophysiological factors that heighten addiction relapse risk. Additionally, Dr. Eddie is conducting research aimed at developing cutting-edge, mobile health (mHealth) interventions driven by wearable biosensors. He is also interested in addiction treatment and recovery processes, as well as drug and treatment policy, and is membership chair for the American Psychological Association’s Society of Addiction Psychology. A licensed clinical psychologist, Dr. Eddie received his BA from Columbia University with honors in psychology, and his PhD from Rutgers University, where he conducted research at the Center of Alcohol Studies. Dr. Eddie undertook his clinical residency at Mass General before completing his postdoctoral training as a Harvard Medical School Livingston fellow at the Recovery Research Institute.
Director of Neuroscience for CAM, Neuroscientist, Principal Investigator, Assistant Professor in Psychiatry, Harvard Medical SchoolPublications
Dr. Gilman received her BS from Tufts University and her PhD in Neuroscience from Brown University, where she used neuroimaging techniques to study the acute and long-term functional and structural effects of alcohol on brain regions involved in motivation and emotion. She came to CAM in January 2013 to study the effects of cannabis in adolescents and young adults. She is the recipient of the Norman Zinberg Fellowship in Addiction Psychiatry from Harvard Medical School, as well as a Career Development Award from the National Institute on Drug Abuse entitled “Neurobehavioral Characterization of Social Influence in Drug Addiction.” Dr. Gilman’s work has been featured in media outlets throughout the world, including Reuter’s, NPR’s Science Friday broadcast, and the BBC.
Postdoctoral Research Fellow
Dr. Lauren Hoffman is a postoctoral research fellow at Mass General and Harvard Medical School. She received her PhD in psychology from the University of Florida, where she was trained in the foundations of behavioral and cognitive neuroscience. Her academic focus has largely concerned the study of alcohol and drugs, both licit and illicit, and how they affect the central nervous system and human behavior. She has expertise in neurophysiological techniques (EEG) and neuropsychological testing, as it relates to addiction psychology. At the Recovery Research Institute, her scientific interests center around the study of substance use disorders, their treatment and mechanisms of successful recovery. Her efforts are currently aimed at studying the differential effects of medication assisted treatments for opioid use disorder on cognition, craving, and psychosocial functioning, and how these factors relate to recovery outcomes. Outside of the Recovery Research Institute, Dr. Hoffman provides national service to the American Psychological Association’s Society of Addiction Psychology and the Research Society on Alcoholism by serving on their membership committees as representative and vice-chair, respectively.
Senior Research Scientist, Recovery Research InstitutePublications
Bettina Hoeppner, PhD is an experimental psychologist who specializes in addiction science. After completing her graduate training in statistics (MS in 2005) and experimental psychology (PhD in 2007) at the University of Rhode Island, and postdoctoral training in addictions at Brown University, she joined the faculty at Mass General and Harvard Medical School, where she conducts research on the active ingredients underlying addictive behavior change to enhance the effectiveness of existing and emerging interventions for individuals seeking to overcome problematic substance use. Much of her recent work has focused on the role mHealth technologies play in supporting addictive behavior change. In this area, she and her team have examined ‘consumer’ interest in smartphone apps to support behavioral change to quit smoking or quit problematic drinking, conducted mediational work to identify the mechanisms by which text-messaging program confer benefit, and are currently conducting a series of studies to develop a smartphone app to support smoking cessation by leveraging advances made in positive psychology.
Dr. Keles is conducting research using multi-modal imaging to detect the effects of acute intoxication on brain function. He received his PhD in Biomedical Engineering from University of Houston. He has received training in optical neuroimaging, electrophysiology, and nano- and micro-scale technologies. His aim is to apply his background in engineering to biology and medicine. Currently, Dr. Keles focuses on the neuroimaging techniques to understand the acute and long-term effects of cannabis on the brain.
Project Director, “Integrated Smoking Cessation Treatment for Smokers with Serious Mental Illness”
Dr Maravic received her BA from the University of Minnesota, Twin Cities and her MPH with a concentration in epidemiology and biostatistics from the Boston University School of Public Health. She joined CAM as a research fellow in 2005, where she focused on identifying predictors of smoking cessation among those with schizophrenia. She received her PhD in Medical Anthropology and Social Science Research Methods from the University Professors Program at Boston University. Her research interests are understanding and improving the health and mental health of vulnerable populations, with a specific focus on addiction, trauma and psychotic disorders. After spending several years as director of research and evaluation at a Latino community health center and as director of analytics and behavioral science at a health engagement management company, she has returned to CAM as Project Director of the Patient‑Centered Outcomes Research Institute (PCORI) project “Integrated Smoking Cessation Treatment for Smokers with Serious Mental Illness”.
Director of Dual Diagnoses Studies at the Depression Clinical Research Program, Principal Investigator, Assistant Professor in Psychology, Harvard Medical School
Dr. Pedrelli is a clinical psychologist with expertise in comorbid disorders. She received her PhD in Clinical Psychology from the Joint Doctoral Program at University of California San Diego and San Diego State University and completed her post-doctoral work at MGH. Her program of research focuses on explicating the etiology of co-occurring mood disorders and alcohol use disorders and on developing psychosocial treatments for these conditions. She has been awarded funding from Harvard Medical School, the National Institute Of Alcohol Abuse and Alcoholism, and the ABMRF/The Foundation for Alcohol Research. Her current work includes a study examining the effectiveness of a novel psychosocial intervention for heavy drinking and depressive symptoms in college students, and a multi-method study investigating positive and negative reinforcement processes at the bases of binge drinking. She has published and presented extensively on the co-occurrence of depressive symptoms and substances use among college students. She is an expert in the delivery of CBT and developed several CBT based treatment manuals for patients with co-occurring disorders.
Dr. Schuster received her BA from University of Maryland, College Park and her PhD in Clinical Psychology from University of Illinois at Chicago. In graduate school, she was funded by a NIDA National Research Service Award to study the cognitive effects of cannabis and tobacco use among at-risk young adults using ecological momentary assessment. She joined CAM in July 2014 as a post-doctoral fellow after completing her clinical internship in neuropsychology at MGH/Harvard Medical School. She is the recipient of the Norman Zinberg Fellowship in Addiction Psychiatry and the Livingston Fellowship from Harvard Medical School as well as the Louis V. Gerstner III Research Scholar Award from MGH. She is currently conducting research based out of Boston-area high schools on the utility of contingency management interventions in promoting cannabis abstinence as well as the reversibility of cognitive deficits during 30 days of cannabis discontinuation.
Postdoctoral Research Fellow
Dr. Vilsaint is a principle investigator at the Recovery Research Institute and Center for Addiction Medicine, and a research fellow at Harvard Medical School. Her research focuses on addiction recovery capital, reducing discrimination among individuals in recovery, and racial health equity in remission and recovery. Dr. Vilsaint is a community psychologist whose work has been recognized by an award from the American Psychological Association. She has been supported by an F31 from the National Institute on Drug Abuse (NIDA) and is currently supported by an F32 from National Institute on Alcohol Abuse and Alcoholism (NIAAA).
Biostatistician, Center for Addiction Medicine and Biostatistics Center
Haiyue Zhang received her BA in science with a concentration in bioinformatics from Stony Brook University and completed the Master’s Biostatistics program at the Harvard T.H. Chan School of Public Health. Her thesis was entitled “Variable Selection Under Multiple Imputation For Missing Data". Her expertise includes data management, statistical modeling, survival analysis, and longitudinal analysis. Haiyu applies her background in biology and applied mathematics to her research and has research experience in the regulation of gene expression during Drosophila early development.
Clinical Research Coordinator
Alexandra Abry graduated from Bates College, where she received her bachelors degree in psychology. At the Recovery Research Institute, Alexandra has worked on a variety of projects, including the Cochrane review on Alcoholics Anonymous and 12-Step Facilitation, a SAMHSA systematic review on recovery support services, the National Recovery Study, and the Recovery Community Center study, among others. She plans to pursue a PhD in clinical psychology.
Nour Azzouz graduated from Wellesley College, where she majored in Neuroscience. Currently, she is involved in three NIH funded clinical studies, including the Nicotine Reduction in Cigarette Smokers trial, the Decision-Making and Drug Use trial and the Neural mechanisms of Food-Related Emotion Regulation trial. Her general areas of study include adolescent psychiatry, developmental neuroscience, and the neural correlates of decision making, emotion regulation, and addiction. She is primarily interested in investigating the neurobiological effects of childhood trauma on brain development.
Hannah Carlon received her bachelor’s degree in psychology from Suffolk University. She was a research intern with the Center for Addiction Medicine during her senior year of college before transitioning to her clinical research coordinator role at the Recovery Research Institute. Hannah works on a variety of projects and studies including: a project to develop smartphone application-delivered treatments for smoking cessation, a study examining social network site engagement in substance use disorder treatment outpatients, and a study examining mutual help organization participation in adults with alcohol use disorder. She plans to pursue a PhD in clinical psychology.
Senior Clinical Research Coordinator
Nilo Fallah-Sohy graduated from the University of Maryland, where she majored in psychology. At the Recovery Research Institute, she has been the lead coordinator of multiple studies and projects, including 1) The Recovery Community Center study which aimed to characterize and evaluate Recovery Community Centers across New England and New York, and 2) Examining the Effectiveness of a Peer Support Model for Parents and Caregivers of Addicted Loved Ones, a study of Learn to Cope members and their engagement with, and perceived benefit of membership in, the Learn to Cope organization, and 3) The Power of Perceptions and Understanding, a four-part live webinar series produced with SAMHSA. Nilo also serves as the grants manager for the RRI, and has played an integral role in submitting several grant applications for NIH funded studies (e.g., R01s, K24s, etc.) and manages several existing NIH funded studies (e.g., 1R01AA026288-01, R01AA025849-01A1, K24AA022136-01, R21AA022693-01A1) and other government contracts (e.g., HHSS283201200031I/ HHSS28342002T ). She plans to pursue a PhD in Clinical Psychology and is interested in substance use and co-occurring disorders, as well as improving screening and prevention for these disorders in educational settings.
Madeleine Fontaine graduated with her BA in Psychology from Clark University. At CAM she is working primarily on the Patient-Centered Outcomes Research Institute funded study investigating integrated smoking cessation treatment for smokers with serious mental illness. Her research interests include the intersection of race, class, and gender on addiction and substance use.
Adrian Lambert graduated from Suffolk University with a degree in biology. He began working with the Center for Addiction Medicine as an intern during his final semester as an undergraduate and is now a clinical research coordinator for the Recovery Research Institute, where he is lead on the Long-term Recovery Study. Adrian is interested in pursuing an MD or PhD to further his knowledge in biology and/or health related sciences.
Jessica Powers graduated with her BA in Psychology and Sociology from Northwestern University. While at CAM, she has been a Clinical Research Coordinator on the Proof-of-Concept Trial of an Alpha-7 Nicotinic Agonist for Nicotine Dependence. Her research interests include the commorbidity of substance use and mental illness, along with the influence of affect, specifically anhedonia, on smoking cessation.
Research Coordinator, Programmer
Milena Radoman, who was born and raised in Montenegro, graduated from Wellesley College, where she majored in Neuroscience. At CAM she works primarily with Dr. Gilman on the acquisition of neurocognitive data, fMRI, and fNIRS analysis. Additionally, she designs and programs computer tasks needed for the studies and helps run analytical software used at CAM. Her research interests include understanding the neuroscience underlying nicotine addiction as well as decision-making and social influence in people who smoke marijuana and suffer from major depressive disorder. She is a language enthusiast and enjoys wilderness activities.
Alexandra Plante executes on communications-related projects for the Recovery Research Institute, working to translate addiction science through media and narrative. She is involved in written and visual content across social media, the recoveryanswers.org website, the Recovery Bulletin monthly newsletter, and coordinates media inquiries and partnerships for the institute. Alexandra received her BA in communication at the University of Massachusetts and her MA in quantitative research in communication from the University at Buffalo.
The Center for Addiction Medicine (CAM) is one of the major clinical research programs of the Department of Psychiatry at Massachusetts General Hospital. CAM delivers clinical evaluation, consultation and study-related clinical care in a multidisciplinary setting.
CAM offers outpatient treatment through several programs:
ARMS is an outpatient clinic that specializes in care for youth ages 14-26 suffering from substance-related problems. The program gives families rapid access to information and provides support services for both youth patients and their families. ARMS also conducts outreach and care management for their patients.
Learn more about ARMS services
The West End Clinic is an outpatient facility for those with alcohol and drug addictions, co-occurring mental health disorders and other types of addictive behaviors. The clinic offers both outpatient therapy and medication treatments in addition to other resources and support services.
Learn more about the West End Clinic
The Recovery Research Institute offers resources to individuals in recovery and those seeking help with addiction, along with resources for family, friends and clinicians looking for ways to help a loved one.
Visit the Recovery Research Institute
CAM also provides treatment through our clinical trials. The program conducts clinical trials related to many aspects of substance abuse disorders, including pharmacological and behavioral treatments of addiction, as well as the impact of addiction together with other conditions.
See our current clinical trials
The Center for Addiction Medicine (CAM) is involved in various collaborative efforts with clinics within Massachusetts General Hospital, Harvard Medical School, MIT and Tufts University, as well as community agencies in the Boston area.
Our research is always changing, but some of our recent research has included the following:
Currently, the program is engaged in multiple clinical trials studying pharmacological and behavioral treatments of alcohol, nicotine, marijuana and cocaine dependence, as well as the impact of addiction together with other mental health conditions.
Learn more about our clinical trials
The Recovery Research Institute's website (RRI) is a non-profit research institute of Mass General's Department of Psychiatry and Harvard Medical School (501(c)(3)) located in Boston. In recognition of the increased public health and broader societal harms related to substance use disorders and the lack of emphasis on research pertaining to how individuals achieve remission and sustain long-term recovery, the Recovery Research institute was created in 2012 under the direction of John F. Kelly, PhD, with a goal of enhancing the public health impact of addiction recovery science through the summary, synthesis and distribution of scientific findings and the conduct of novel research investigation.
The Recovery Research Institute is home to the Recovery Research Review, a free electronic monthly publication containing contextualized summaries and syntheses of the latest research in addiction treatment and recovery. In addition, the RRI serves as a teaching and training center for promising researchers in addiction, funding two to three postdoctoral fellows each year.
In 2016, the Recovery Research Institute developed the MAPS software, groundbreaking in its ability to assist in the dynamic assessment of individuals with substance use disorders across clinical settings. The RRI worked also to expand its “Addiction-ary” to over 100 addiction-related terms and began a national effort to fight the stigmatization of addiction, leading the way in helping to align the language of addiction to be consistent with a broader public health approach to addressing substance use disorders.
In research for 2016, the RRI conducted the first study on the prevalence and pathways of addiction recovery using a nationally representative sample of 50,000 US adults, and the first ever study to characterize participation and benefits of online recovery support networks using the social network site InTheRooms.com.
Visit the Recovery Research Institute's website to learn more.
Mass General is an integrated full-service primary, secondary and tertiary care hospital network with access to large numbers of diverse local patients, making it an ideal setting for clinical research in addiction. The hospital is home to thousands of basic and clinical scientists and collaboration is encouraged.
Each year up to three clinical fellows receive training in the Addiction Psychiatry Fellowship. Matriculants are board-eligible in addiction psychiatry.
We are pleased to announce a new K12 Career Development Program in Substance Use and Addiction Medicine based at the Massachusetts General Hospital and funded by the National Institute on Drug Abuse of the National Institutes of Health. This program is a collaboration between the Departments of Medicine and Psychiatry at Mass General led by A. Eden Evins, MD, MPH (Psychiatry) and Nancy Rigotti, MD (Medicine).
This program for promising postdoctoral clinicians-scientists provides salary, training and project support for two to five years of intensive mentored research training and career development. The program is ideal for candidates who aim to establish independent research programs in patient-oriented substance use and addiction research.
Research and training proposals are sought on a broad range of substance use and addiction medicine topics, including laboratory, clinical or epidemiologic research into such topics as:
Applications due: February 23, 2018
Learn more and apply
This one-year, full-time addiction fellowship offers exposure to a wide range of clinical opportunities at Mass General, Brigham and Women’s Hospital and McLean Hospital, as well as opportunities for translational research and clinical trials focused on the development of novel behavioral treatments of addiction, genetics and neuroimaging components. There is also particular interest in development of surrogate markers of treatment response and relapse.
Fellows may work on projects funded by the National Institute on Drug Abuse (NIDA), or they can work with Eden Evins, MD, MPH or John Kelly, PhD to seek grant support for a fellowship.
Learn more about the fellowship
The Center for Addiction Medicine (CAM) is strongly committed to training psychiatry residents, fellows, and psychology interns. CAM actively provides education for local and visiting medical students and residents who participate in twice weekly rounds, individual supervision, case presentations and three to five monthly didactic lectures. CAM’s expert, multidisciplinary team translates scientific findings and applies evidence-based clinical strategies to create new models of care, leading to more favorable outcomes for this large but inadequately served population.
Office location:101 Merrimac Street, Suite 320Boston, MA 02114
Administrative Phone: 617-643-4691Study Phone: 617-724-8472Fax: 617-643-1998
Learn more on our Center for Addiction Medicine site.
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