Research & Clinical Trials at the Department of Radiation Oncology

Research is an essential part of the MGH Department of Radiation Oncology's mission. Clinical research, basic research and physics research are conducted into the causes and mechanisms of cancer, with an emphasis on translating that work to clinical application, so that we can offer patients the benefits of these advances.

Research Labs

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  • Biostatistics & Biomathematics

    The Division of Biostatistics & Biomathematics supports research-oriented databases and data management needs for Radiation Oncology.

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  • Cellular & Molecular Radiation Oncology Laboratory

    Working at the cellular and molecular levels, our studies cover a range of topics, including mechanisms of cell death, DNA damage induction and repair processes, bystander effects, and cancer genetics.

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  • Edwin L. Steele Laboratories for Tumor Biology

    The Edwin L. Steele Laboratories are committed to improving the prevention, detection and treatment of cancer in patients through a better understanding of tumor pathophysiology and host-tumor interactions.

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  • Pediatric Radiation Oncology Clinical Research

    The mission of the Pediatric Radiation Oncology Research program is to continuously improve cancer treatment and outcomes in our pediatric patients through innovative and collaborative research that we translate into clinical care.

  • Physics Research for Radiation Oncology

    Research efforts are focused on developing radiation treatment techniques to optimize physical dose conformation to the tumor target volume and to increase the precision of the dose application.


PARTIQoL: Prostate Advanced Radiation Technologies Investigating Quality of Life

PARTIQoL is the first randomized trial of its kind and is enrolling patients with low or intermediate risk prostate cancer across the United States. The goal of the trial is to study two types of radiation therapy: Intensity Modulated Radiation Therapy (IMRT) and Proton Beam Therapy (PBT).

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