Gynecologic Program

Using cutting edge technology including intensity modulated radiation therapy, proton therapy, intraoperative radiation, and brachytherapy our team of dedicated radiation oncologists treat a wide variety of gynecologic malignancies.


The Gynecologic Radiation Oncology Service is nationally recognized in the field of radiation oncology for providing comprehensive clinical care for women with primary cancers of the uterus, cervix, vulva, vagina, ovaries, and fallopian tubes. Centered on reproductive-tract tissues, gynecologic radiation therapy requires exceptional precision to minimize the impact of treatment on sexual, hormonal, and reproductive functions. Our radiation oncologists' extensive knowledge of reproductive anatomy and physiology, combined with their expertise in radiation therapy, make them exceptionally qualified to treat women with gynecologic cancers.

Clinical Services and Special Programs

  • Brachytherapy: Our service has made significant clinical advancement with the treatment of medically inoperable uterine cancers with intra-cavity brachytherapy using CT compatible titanium applicators and CT-based Dosimetry
  • Consolidative or whole abdomen radiation treatment: Following surgery and chemotherapy for patients with FIGO stage III and abdomen confined stage IV cancers of the uterus this treatment employs intensity modulated radiation therapy (IMRT)
  • Sequential tri-modality therapy: Patients with FIGO stages IIC1 and IIIC2 uterine cancers with extra-uterine cancer limited to retroperitoneal nodes are treated with surgery, adjuvant systemic chemotherapy, and consolidative extended volume pelvic/ para-aortic node radiation
  • Proton Therapy: As a pioneer of proton therapy, Mass General offers multi-modality treatment of cancer of the uterus with metastases to regional nodes

Areas of Excellence

Mass General offers multi-modality treatment of cancer of the uterus with metastases to regional nodes (stage IIIC), where Mass General clinical outcomes are currently among the best reported in the medical literature (in excess of 80% five-year relapse-free actuarial survival).

Meet the Team

Patient Education

Our team is dedicated to keeping you completely informed and encourages your questions about any step in the treatment process, from understanding the safety of your therapy to managing side effects. Answers to many frequently asked questions also appear in Your Guide to Radiation Therapy (PDF).

Female Sexual Health Clinic
If you are a female patient who has received or are currently receiving pelvic radiation and are concerned about how your cancer diagnosis may be affecting your sexual health, interventions offered by our Female Sexual Health Clinic may be able to help.

Clinical Trials

Massachusetts General Hospital invites patients and the community to participate in innovative clinical trials and research studies.

Search open clinical trials.


Contact Us

Clark Center for Radiation Oncology

Vida E & Arthur L. Goldstein Lunder Building

55 Fruit StreetLunder Building LL3 Boston, MA 02114
  • Near Public Transit
  • Accessible
  • Phone: 617-726- 8651
  • Fax: 857-238-6377
  • Email Us

Francis H. Burr Proton Therapy Center
30 Fruit Street
Boston, MA 02114
Phone: 617-726-0923 (Proton Inquiry Line: 617-724-1680)
Fax: 617-726-6498


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