The translation of scientific discoveries to clinical practice is rapidly rising on the list of research priorities, as stakeholders adjust to changing realities regarding:

  • The levels and sources of funding for biomedical research
  • Increasing sponsor expectations for clinically relevant and commercially viable research results
  • Growing recognition that pressing biomedical problems have a better chance of being solved in research environments with contributors from multiple disciplines

Massachusetts General Hospital is ideally positioned to contribute to and benefit from this burgeoning emphasis on translational research. Its mission—to excel in clinical medicine and scientific research, and to lead in training for both—contains the essential ingredients for successful translational research initiatives that will improve patient care.

We do this by:

  • Launching training programs in translational research (teaching our investigators how to interact with industry)
  • Collaborating in early-stage translation through our Strategic Alliances initiative
  • Opening the Translational Research Center, an 18-bed in-patient facility for proof-of-concept clinical trials
  • Creating a series of "Think Tanks" that bring together researchers, venture capitalists and members of industry to brainstorm solutions for challenges in rare diseases, neurodegeneration and other key areas of need

The Translational Research Center

  • This $11M facility is an 18-bed, state-of-the-art clinical research space in the heart of the Mass General campus
  • It fully staffed by experienced nurse practitioners, clinical research nurses and support staff
  • By conducting their studies at the TRC, industry members can gain access to Mass General clinicians and investigators, many of whom are leading experts in biomarkers, imaging, molecular biology, drug development and other crucial areas of biomedical research
  • The TRC also provides access to the comprehensive assessment and monitoring resources of Mass General such as novel laboratory tests, radiology department PET scanning and other imaging studies that are not typically available in typical phase 1 facilities

Learn more about the TRC


Strategic Alliances Initiative

The Strategic Alliances initiative is a cornerstone of the Research Institute’s mission to help scientists engage in more productive and long-lasting collaborations with industry at all stages of their work: from fundamental research to proof of concept, development, and transfer to market and patient care.

The three pillars of the Strategic Alliances initiative are:

  • Developing a comprehensive research portfolio to connect our investigators with industry partners.

  • Creating cross-departmental, problem-driven research programs. This new approach combines intra-institutional collaborative structures with outreach approaches that extend the collaborative model to commercial partners. It leverages our high quality fundamental and translational research with our world class clinical care and patient-derived resources. It also provides opportunities for early business development input.
  • Running a joint academia-industry translational research training program to develop future academic leaders that can work not only across multi-disciplinary scientific domains, but also understand the scientific and business principles that underlie translational research and move innovation to patient care through robust collaborations with industry.

Learn more about Strategic Alliances

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