Alzheimer's disease imaging signature

Dickerson Lab

Researchers in Brad Dickerson's Laboratory seek to understand the relationships between brain anatomy, physiology, and behavior in humans across the lifespan and in those with neurodegenerative diseases.

Lab Phone: 617-726-5571

Neurology Access Center 1-855-644-6387


Major focus areas of our research include: memory abilities and the brain systems that subserve them in normal individuals and how these abilities and brain systems change with aging, Alzheimer's disease, and related disorders (including frontotemporal dementias and posterior cortical atrophy); understanding how aging, Alzheimer's disease, and related disorders alter the normal anatomy and function of the human brain, and determining whether this knowledge can assist in diagnosis and monitoring of these conditions; and the further development of new neuroimaging and behavioral technology for making quantitative measurements of these abilities and brain systems.

We are also pursuing studies of language and semantic knowledge in progressive aphasias; and social cognition and affective processing in normal aging and how these are affected by frontotemporal dementias and Alzheimer's disease.

In addition, we pursue some investigations related to the development and promotion of capacities to compensate for age- and disease-related changes.

Group Members

Brad dickerson, research investigator

Principal Investigator

Brad Dickerson, MD

  • Associate Professor of Neurology,
    Harvard Medical School
  • Director of Clinical Applications,
    Morphometry Service
    Massachusetts General Hospital,
  • Co-Director, Neuroimaging Group,
    Gerontology Research Unit

Research Scientists

  • Liang Wang, MD - Radiologist, Post-Doc Fellow
  • Kimiko Domoto-Reilly, MD - Behavioral neurology fellow
  • Scott McGinnis, MD - Behavioral neurologist, junior faculty fellow
  • Belen Pascual, PhD - Psychologist, Post-Doc Fellow
  • Kristen Lindquist, PhD - Post-Doc Fellow
  • Daisy Sapolsky, MS, CCC-SLP - Speech and Language Pathologist

Research Assistants & Technicians

  • Mike Brickhouse, BS - Research Assistant
  • Mark Hollenbeck, BS - Research Assistant
  • Aly Negreira, BA - Study coordinator/Research assistant

Contact Us

Brad Dickerson, MD

Research Projects

The Dickerson lab is pursuing the following major lines of research:

  • Anatomy and physiology of normal human memory abilities
  • Anatomy and physiology of impaired human memory
  • Anatomy of aging, MCI & Alzheimer's disease
  • Ultrahigh-resolution MRI imaging methods
  • Brain-behavior relationships in focal cortical neurodegenerative syndromes
  • Semi-quantitative and quantitative clinical and behavioral characterization of progressive aphasias, frontotemporal diseases, and Alzheimer's disease

For details, visit theDickerson research lab website


Visit the Dickerson Lab website for a complete list of publications.

Lab Phone: 617-726-5571

Neurology Access Center 1-855-644-6387

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