PET Core Laboratory

The PET (positron emission tomography) Core Laboratory provides a full range of technical and professional services for the design and execution of programs using PET.


The Massachusetts General Hospital Gordon PET Core provides a full range of technical and professional services that include:

  • Synthesis of radiotracers and radiopharmaceuticals
  • PET and SPECT animal and human imaging
  • Experimental design and pharmacokinetic modeling
  • Validation and regulatory submission of compound for human use

The Core has synthesized over 20 compounds for clinical evaluation and routine use for neurology, cardiology and oncology. In addition, it has pioneered the use of 18F Tau imaging agents for neurodegenerative diseases such as Alzheimer’s disease and traumatic brain injuries.

The PET Core Facility provides the required facilities and personnel on a per study basis to allow investigators to use PET without requiring them to acquire the needed special expertise and equipment.

Investigators from the academic community, research laboratories and industry are welcome to use the PET Core services. Research services are accessed through contact with the professional staff leading to formalization of a research plan and subsequent review by the Scientific Management Committee. Clinical services are accessed by direct arrangement with the medical staff of the radiology department.

To access the core, please contact Ramsey El Fakhri  at 617-724-7212 or by email at

The PET Core has mechanisms available for pilot studies.



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