Superior sulcus tumors (also known as Pancoast tumors) are an unusual presentation of non-small cell lung cancer (NSCLC). The diagnosis is often delayed. Accurate and thorough staging is necessary before treatment and typically includes magnetic resonance imaging if a surgical approach is being considered. The current therapy consists of a combination of chemotherapy and radiation followed by removal (resection).

Complete resection remains the key to long-term survival in localized NSCLC, but is challenging due to early invasion of bone, blood vessels, and nerves at the top of the chest.

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