The Massachusetts General Hospital Transplant Center is leading the way in New England and the world in basic scientific and clinical transplantation research.
Our groundbreaking work in tolerance induction means that some patients can now avoid taking lifelong immunosuppressive drugs after kidney transplantation. We continue to investigate new approaches to improve transplant success rates, including a new procedure for kidney transplantation between persons with incompatible blood types. We are also working to increase the pool of available donors and enhance quality of life post-transplant.
The Transplant Center offers highly advanced treatments through clinical trials. Current trials involve using a liver assist device in bridge therapy and novel immunosuppressive drugs to decrease hepatitis C reinfection rates after transplantation. In addition to pioneering new treatments for patients with liver failure, we are also working to improve the success of liver transplants through therapies that treat organ rejection.
We are evaluating how a variety of new drugs, medical devices and therapies may increase survival rates and provide alternatives for heart disease patients who are not transplant candidates. We are also investigating whether gene therapy may help reverse heart failure. Our work includes novel approaches to heart care, including noninvasive diagnostic tools and earlier interventions.
Our work in this area explores both lung transplantation and the diseases that cause the need for transplants. Developing treatments include stem cell transplantation to better understand how airways heal and improve transplant results. We are also part of a multicenter trial into a new drug to treat pulmonary fibrosis.
The Transplant Center is one of the few centers in the world to investigate islet cell transplantation, a less invasive alternative to pancreas transplants for patients with type 1 diabetes. Upcoming clinical trials will focus on helping these patients become insulin independent.
Innovative studies are underway to improve the preservation and function of organs from deceased donors. In the future, ongoing laboratory studies may help solve the organ shortage by uncovering alternative sources for organs.
Liver Perfusion Device
Perfusion devices may help solve the organ shortage by uncovering alternative sources for organs. The MGH Transplant Center is a leading site in the field of organ perfusion and preservation.