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Vincent Center for Reproductive Biology
The mission of our center is to overcome infertility, improve health care for non-pregnant and pregnant women, combat gynecologic cancers, and ease the menopausal transition in women through basic, translational and clinical research.
We are recruiting a postdoctoral fellow with expertise in neuroscience to work in the Edlow Laboratory within the Vincent Center for Reproductive Biology.
Our research broadly focuses on the programming effects of maternal obesity/overnutrition on fetal and offspring brain development and behavior. We utilize pre-clinical models to explore mechanisms underlying neurodevelopmental morbidity in obesity-exposed offspring, including but not limited to neuroinflammation, neuroimmune interactions, and the impact of offspring sex.
Our laboratory is affiliated with Harvard Medical School and Massachusetts General Hospital.
Applicant should have a PhD, ideally in neuroscience, although applicants with a PhD and extensive experience with rodent models, molecular techniques, and immunohistochemistry are also encouraged to apply.
The Edlow Laboratory for basic and translational research is sited in the Vincent Center for Reproductive Biology (VCRB) on the main campus of Massachusetts General Hospital.
Ongoing studies focus on the neurodevelopmental programming effects of maternal obesity and maternal high-fat diet during pregnancy and lactation. The work is primarily with a mouse model of maternal diet-induced obesity.
We evaluate fetal, juvenile, and adult offspring brain development using molecular and immunohistochemical techniques, as well as neurobehavioral testing. Areas of focus include: (1) the effects of maternal diet-induced obesity on offspring cognition and mood outcomes (anxiety, depression), particularly as they relate to neuroinflammation and brain-immune interactions; (2) Developmental programming of offspring feeding behaviors (reward-based feeding governed by the mesolimbic dopamine circuit) and offspring metabolic parameters (including insulin resistance, body fat composition, and dysregulation of leptin, ghrelin, and other peripheral and central hormonal signaling); (3) Utilizing novel targeted therapeutics to improve offspring neurodevelopmental outcomes; and (4) Elucidating the role of fetal and offspring sex in mediating the effects of maternal diet-induced obesity on neurodevelopment.
The position requires:
There are many opportunities for education and growth in our multidisciplinary, collaborative research program that brings together a diverse group of obstetrician-gynecologists, neuroscientists, immunologists, endocrinologists, animal neuroimagers at the world-class Athinoula Martinos Center for Brain Imaging, and translational and clinical researchers at the Women Heart Brain Global Initiative.
Please email a CV and cover letter of interest to Ms. Becky Rogers, Administrative Assistant for the Vincent Center of Reproductive Biology, at firstname.lastname@example.org, indicating that you are applying for the postdoctoral position in Dr. Edlow’s lab.
Two letters of reference and a brief writing sample will also be requested during the interview process.
Research Fellow Position in the Wang Lab
A Postdoctoral Research Fellow position is available in the Vincent Center for Reproductive Biology (VCRB), Department of Obstetrics and Gynecology, Massachusetts General Hospital. Our research mainly focuses on discovering new strategies to improve prevention, early detection, and treatment of ovarian and cervical cancers. Learn more about research in the Wang Lab.
The ideal applicant will have a graduate degree in the biological sciences (PhD, MD, or MD/PhD) with proven proficiency in cell/molecular techniques. Strong background on immunology and cancer immunotherapy is preferred.
Candidates with experience in generating transgenic mouse model are strongly encouraged to apply. Interested candidates should send a cover letter, curriculum vitae and contact information of three professional references (names, address, phone and e-mail) to Ms. Bakhyt Rogers, Administrative Assistant, Vincent Center for Reproductive Biology, Massachusetts General Hospital, THR-901, 55 Fruit Street, Boston, MA 02114.
For further information regarding this position please contact Dr. Wang by email.
Massachusetts General Hospital is a teaching affiliate of Harvard Medical School and an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, protected veteran status or status as an individual with a disability.
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