Mass General for Children Research Day
Presented by the Mass General for Children Scientific Advisory Board annually in the spring, Research Day highlights recent accomplishments and advances from Mass General researchers, as well as from the broader pediatric research community.
Save the Date for Research Day 2020: “Women in Science"
Tuesday, May 19, 2020
8:00 am – 3:00 pm
Shriners Hospital, 1st Floor Auditorium & MGH Bulfinch Tent
MGH Keynote Speaker
Dr. Patricia K. Donahoe, MD
Director Pediatric Surgical Research Laboratories
Chief Emerita, Pediatric Surgical Services, MGH
Marshall K. Bartlett Professor of Surgery, HMS
Visiting Keynote Speaker
Dr. Rita Colwell, PhD
Distinguished University Professor
University of Maryland
National Medal of Science Awardee, 2006
Agenda also includes short talks by MGfC faculty followed by the poster session.
Call for Abstracts
Faculty, nurses, fellows, residents, post-docs and other trainees at MGH engaged in pediatric research are invited to submit their research and present at the poster session to compete for multiple awards sponsored by the Pediatric Translation Research Center at MGfC.
Research Day 2019
Date: Tuesday, May 7th, 2019, 8:00 am – 3:00 pm
Location: Shriners Hospital's 1st Floor Auditorium, 51 Blossom Street (across the street from MGH Thier Building)
MGH Faculty Keynote Speaker:
Guillermo J. Tearney, MD, PhD
Professor of Pathology, Harvard Medical School
Remondi Family Endowed MGH Research Institute Chair
Mike and Sue Hazard Family MGH Research Scholar
Pathologist, Massachusetts General Hospital
Physicist, Massachusetts General Hospital
Faculty, Wellman Center for Photomedicine
Visiting Keynote Speaker:
Timothy K. Lu, MD, PhD
Associate Professor of Biological Engineering and Electrical Engineering and Computer Science, Massachusetts Institute of Technology
Core Faculty Member, Synthetic Biology Center
Associate Member, Broad Institute of MIT and Harvard
Member, Research Laboratory of Electronics
The program also includes four short talks by MGfC junior faculty and an afternoon poster session in the Bulfinch Tent. A “Call for Abstracts” will be sent in February inviting all faculty, nurses, fellows, residents, post-docs and other MGH trainees engaged in pediatric research to submit one or more research abstracts to be presented at the poster session. All presenters will be considered for awards sponsored by the Pediatric Translational Research Center at MGfC.
Research Day 2018: 10th Anniversary Celebration
Date: Tuesday, March 20th, 2018 8:00 am – 3:00pm
Location: Starr Center, 185 Charles River Plaza
Visiting Keynote Speaker:
Diana W. Bianchi, MD
Director of the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD).
MGH Faculty Keynote Speaker:
Randy L. Buckner, PhD
Professor of Psychology and Neuroscience at Harvard University
Director of the Psychiatric Neuroimaging Research Division at the Massachusetts General Hospital
The program also includes four short talks by MGfC junior faculty as well as an afternoon poster session. A “Call for Abstracts” invites faculty, nurses, fellows, residents, post-docs and other trainees at MGH engaged in pediatric research to submit their research and present at the poster session to compete for multiple awards sponsored by the Pediatric Translation Research Center at MGfC.
Research Day 2017
Date: Tuesday, March 28, 2017
Location: Simches 3rd Floor Conference Center, 185 Cambridge St., Boston MA
Rooms 3110, 3120 and 3130
Schedule of Events
10:30 am to 11:50 am: Posters will be available for viewing
Lunch will be available beginning at 11:30 am for those attending the keynote address and faculty presentations.
11:50 am to 12:00 pm: Opening remarks, Ronald Kleinman, MD, Physician-in-Chief, Mass General for Children
12:00 pm to 1:00 pm:
Keynote Address: Nature, Nurture and Mental Illness
Jordan W. Smoller, MD, ScD
MGH Trustees Endowed Chair in Psychiatric Neuroscience
Professor of Psychiatry, Harvard Medical School
Professor in the Department of Epidemiology, Harvard T.H. Chan School of Public Health
Director, Psychiatric and Neurodevelopment Genetics Unit, Massachusetts General Hospital
Director, Omics Unit, Mass General Division of Clinical Research
Associate Member, Broad Institute
Faculty Speakers: 1:00 pm to 2:10 pm
Elucidating the Early Steps in Shigella Pathogenesis
Christina Faherty, PhD
Assistant Professor of Pediatrics, Harvard Medical School
Assistant Molecular Biologist, Massachusetts General Hospital
Member, Mucosal Immunology and Biology Research Center
Gonadal Hormones and Mood
Charumathi Baskaran, MD
Instructor in Pediatrics, Harvard Medical School
Pediatric Endocrinologist, MGfC
Overdose risk factors in youth with substance use disorders
Amy M. Yule, MD
Instructor in Psychiatry, Harvard Medical School
Assistant in Psychiatry, MGfC
2:15 pm to 3:30 pm: Announcement of Abstract and Concluding Remarks
Ronald Kleinman, MD
Three outstanding abstracts will be selected to receive travel awards to national meetings
Poster Session Awardees:
To be determined at Research Day: Tuesday, March 28th, 2017
Organizers: Bryan Hurley, PhD, Madhusmita Misra, MD, MPH, & Kim Francis, RN, PhD
Research Day Questions contact: Jennifer Virgil at jvirgil@partners.org
Research Day 2016
Keynote Address:
PEDSnet, PCORnet, PROMIS, and PEPR: Four National Research Programs Poised to Transform Child Health
Christopher B. Forrest, MD, PhD
Professor, Pediatrics & Health Care Management
Children’s Hospital of Philadelphia and University of Pennsylvania
Faculty speakers
Vibha Singhal, MD
Instructor in Pediatrics, Pediatric Endocrine Unit
Colors of Fat – Effect on Bone
Peter Moschovis, MD
Instructor in Medicine, MGH Pulmonary and Critical Care Unit and Pediatric for Global Health
Risk factors for poor outcomes in childhood pneumonia
Mona Sharifi, MD
Instructor in Pediatrics, Division of General Pediatrics
Obesity-Related Outcomes of Interest to Families and Clinical Stakeholders in a Childhood Obesity Intervention
Poster Session Awardees
- Marjorie Galler, MD (Mentor: Chadi El Saleeby, MD)The impact of a pediatric-specific nomogram on Vancomycin utilization and prescribing practices at the Massachusetts General Hospital for Children: A glimpse of the way ahead
- Katie Powis, MD, MPH. Significantly Increased Neonatal Mortality of HIV-Exposed Uninfected Formula Fed Infants Compared With Breastfed Infants in Socioeconomically Challenged Households in Bostwana—Findings from the Mpepu Study
- David Sweetser, MD. Tle1 tumor suppressor negatively regulates inflammation in vivo and modulates NF-κB inflammatory pathway
Research Day 2015
Keynote Speaker
Steven M. Holland, MD
“Gain of Function Immunodeficiencies: Too much of a good thing”
Chief, Laboratory of Clinical Infectious Diseases
Chief, Immunopathogenesis Section, LCID
Additional speakers were prior awardees of the Talbot Pilot Feasibility Study Grant from the MGfC:
- Jamie Micco, PhD (Pediatric Psychiatry) (2011 awardee)
- Deborah Mitchell, MD (Pediatric Endocrinology) (2013 awardee)
- Cassandra Michelle Kelleher, MD (Pediatric Surgery) (2014 awardee)
Resident Jack Rowe, MD, presented his research.
Research Day 2014
Keynote Lectures:
“An Overview of Autism Spectrum Disorder” by Christopher J. McDougle, MD, Nancy Lurie Marks Professor of Psychiatry, Director, Lurie Center of Autism
AND
“Is Autism an Autoimmune Disease” by Alessio Fasano, MD, Chief, Division of Pediatric Gastroenterology and Nutrition, Associate Chief, Department of Pediatrics Basic, Clinical and Translational Research, Director, Center for Celiac Research, Director, Mucosal Immunology and Biology Research Center, Mass General for Children, Visiting Professor, Harvard Medical School
MGfC Faculty Lectures
“Cross-talk between the host and enteric pathogens: what do they talk about and what can go wrong when they do not understand each other”
Maria Rosaria Fiorentino, PhD
Lecturer in Pediatrics
“The Influence of Nutritional Exposures on the Preterm Infant Intestinal Microbiome”
Katherine Gregory, PhD
Clinical Instructor in Pediatrics
“Optimizing health and survival of HIV-exposed children in Botswana through research”
Kathleen Powis, MD, MPH
Instructor in Pediatrics
Poster Session Awardees
- Lauren Kleimola (Mentor: Patricia Hibberd, MD, PhD). Stunted growth in early childhood is associated with exposure to household air pollution.
- Nanda Kumar N. Shanmugam, Post-Doctoral Fellow (Mentor: Bobby Cherayil, MD, PhD). Intestinal inflammation modulates expression of the iron regulating hormone hepcidin depending on erythropoietin activity and the commensal microbiota
- Vibha Singhal, MD (Mentor: Madhu Misra, MD, MPH). Irisin levels are lower in young amenorrheic athletes compared with eumenorrheic athletes and non-athletes and correlate with bone structure and strength estimates
Research Day 2013
Keynote Lecture: “Molecular Dissection of the new disorder Eosinophilic Esophagitis”
Stephanie Seminara, MD, Co-Director of the Reproductive Endocrine Associates, Massachusetts General Hospital, and Associate Professor of Medicine, Harvard Medical School
MGfC Faculty Lectures
“Assessing the Safety and Efficacy of Inhaled Nitric Oxide in Cerebral Malaria”
Ryan Carroll, MD, Assistant in Pediatrics, Mass General for Children, Instructor in Pediatrics, Harvard Medical School
“The Preterm Infant's Behavioral Pain Response”
Kim Francis PhD, RN, PHCNS-BC, Neonatal Clinical Nurse Specialist for the Massachusetts General Hospital Obstetric Service, Clinical Instructor for the MGH Institute of Health Professions, Haley Nurse Fellow for Boston College and Brigham & Women’s Hospital
“Effects of Growth Hormone Augmentation on Visceral Fat and Metabolic Risk in HIV-infection”
Takara Stanley, MD, Assistant in Pediatrics, Mass General for Children, Assistant Professor in Pediatrics, Harvard Medical School
Poster Session Awardees
- Mridu Acharya (Mentor: Adam Lacy-Hulbert, PhD). αv integrins use autophagy machinery to modulate specific B cell immune responses
- Peter P. Moschovis, MD, MPH (Mentor: Patricia Hibberd, MD, PhD). Household air pollution and risk of childhood pneumonia death in low and middle income countries
- Deepak Palakshappa MD. Communication discrepancies between Pediatric Residents and Attendings; a supervision dilemma for residency training programs
Research Day 2012
Keynote Lecture: “Molecular Dissection of the new disorder Eosinophilic Esophagitis”
Marc Rothenberg, MD, PhD
Director of Allergy and Immunology at Cincinnati Children's Hospital Medical Center and the Cincinnati Center for Eosinophilic Disorders
MGfC Faculty Lectures
“Immune Therapy in Type 1 Diabetes”
Nicole Sherry, MD
Instructor in Pediatrics, Harvard Medical School
Director, Diabetes Program, Pediatric Endocrinology, Mass General for Children
“Modulation of Mucosal Immunity by Intestinal Helminth Infection”
Haining Shi, DVM, PhD
Assistant Professor of Pediatrics, Harvard Medical School
Mucosal Immunology Laboratory, Mass General for Children
“Use of the Built Environment to Promote Physical Activity in Children”
Nicolas Oreskovic, MD, MPH
Instructor in Pediatrics, Harvard Medical School
Internal Medicine & Pediatrics, Massachusetts General Hospital
Center for Child & Adolescent Health Research and Policy
“Human RAG deficiency: not just immunodeficiency--Novel insights into mechanisms of immune dysregulation”
Jolan Walter, MD, PhD
Clinical Instructor in Pediatrics, Harvard Medical School
Physician, Pediatric Allergy/Immunology, Mass General for Children
Poster Session Awardees
- Elena Grant: Childhood Repair of Tetralogy of Fallot Leads to Long Term Hepatic Dysfunction
- Selvi Ramasamy: The TLE1 Tumor Suppressor Regulates Myc Induced Leukemogenesis
- Ana Sokovska/Christine Becker (co-first author presenters): Rab39a Links Caspase-1 Activation to Phagosome Acidification and Cellular Defense
Research Day 2011
Keynote Lecture: “Stem and Progenitor Cells in Neonatal Lung Injury and Repair”
Dr. Vivek Balasubramaniam
Univ. of Colorado – Director of Pediatric Heart Lung Center
MGfC Faculty Lectures
Elahna Paul, MD, PhD
Instructor in Pediatrics, Harvard Medical School
Pediatric Nephrology, Mass General for Children
Jonathan Spector, MD
Instructor in Pediatrics, Harvard Medical School
Neonatology and Newborn Medicine, Mass General for Children
Ann-Christine Duhaime, MD
Nicholas T. Zervas Professor of Neurosurgery
Pediatric Neurosurgery, Mass General for Children
Poster Session Awardees
- Mauro Longoni. Diaphragmatic hernia: genetic dissection of a complex birth defect. Laboratory of Patricia K. Donahoe
- Jay Thiagarajah. Airway surfactant liquid depth imaged by surface laser reflectance microscopy. Laboratories of Jay Thiagarajah and A.S. Verkman.
- Orane Visvikis. Involvement of HLH-30/MiT transcription factors in intestinal epithelial immunity. Laboratory of Javier E. Irazoqui
Research Day 2010
Keynote Lecture: “Update on Obesity Research”
Lee Kaplan, MD, PhD
Director, MGH Weight Center
MGfC Faculty Lectures
“Immunity to Cholera”
Jason Harris, MD
Assistant Professor of Pediatrics, Harvard Medical School
Pediatric Infectious Disease Division, Mass General for Children
“Primary Care Management of Chronic Conditions in Pediatrics”
Jeanne Van Cleave, MD
Instructor of Pediatrics, Harvard Medical School
Academic General Pediatrics Program, Mass General for Children
“Innate Immunity – Learning on the Fly”
Lynda Stuart, MD
Assistant Professor of Pediatrics, Harvard Medical School
Developmental Immunology Program at Mass General for Children
Poster session awardees:
- Leah Jacoby - Total and site-specific fat and lean mass as predictors of bone density in female adolescent athletes – working with Dr. Madhu Misra in Pediatric Endocrinology at Mass General for Children
- Patricia Rodriguez Bachiller - TGF-ß decreases expression of NO signaling enzymes in the injured newborn lung and in vascular smooth muscle cells -working with Jesse Roberts in the Pediatric ICU at Mass General for Children
- Helena Paidassi - Description of novel innate activation of macrophage: Role in host immunity and intestinal immunopathology - work with Adam Lacy-Hulbert in Development Immunology at Mass General for Children
Research Day 2009
Keynote Lecture: “Genomics and the study of Clinical Diseases”
David Altshuler, MD, PhD
Professor of Genetics and Professor of Medicine, Harvard Medical School
Director, Broad Institute, Program in Medical and Population Genetics
MGfC Faculty Lectures
“Skeletal Effects of Anorexia Nervosa in Adolescents”
Madhu Misra, MD, MPH
Assistant Professor of Pediatrics, Harvard Medical School
Pediatric Endocrinology, Mass General for Children
“Ironing out the wrinkles in host defense: interactions between innate immunity and iron homeostatis”
Bobby Cherayil, MD
Associate Professor of Pediatrics, Harvard Medical School
Mucosal Immunology Laboratory, Massachusetts General Hospital
“Making a brain in the gut: molecular development of the enteric nervous system”
Allan Goldstein, MD
Associate Professor of Surgery, Harvard Medical School
Pediatric Surgery, Mass General for Children
Poster Session Awardees
- Volodymyr Dzhala (Kevin Staley's lab) - Chloride accumulation and phenobarbital failure in neonatal seizures.
- Marshall Karpel (Emmet Schmidt's lab) - A novel L-ficolin-mannose binding lectin chimeric molecule with enhanced activity against lethal viral infections.
- Jianfeng Wang (David Sweetser's lab) - Groucho/TLE corepressors regulate myeloid differentiation and size of the stem cell/progenitor population