Dr. Young, a native of Northern Ireland, is a 1974 graduate of Dublin University. After early training there in the University Pathology Department he joined the Massachusetts General Hospital in 1977, where he completed a residency. He then did a fellowship in gynecologic pathology under the direction of Dr. Robert E. Scully and joined the faculty in 1981. He is the Robert E. Scully Professor of Pathology at Harvard Medical School and his primary interest is gynecologic pathology with a strong secondary interest in urologic pathology. Dr. Young has written over 400 original publications, numerous reviews and book chapters and has authored or edited 13 books. His papers on gynecologic pathology have been broad but with an emphasis on ovarian tumors. In both gynecologic pathology and urologic pathology, he has a strong interest in non-neoplastic mimics of neoplasia and has also had a major interest in testicular tumors. Among many awards, he received the Fred Waldorf Stewart Award of Memorial Sloan Kettering Cancer Center (2015), the Leopold Koss Lifetime achievement award for contributions to urologic pathology (2011) and the President's Medal, British Division of the International Academy of Pathology for Contributions to Education (2019). His educational activities have included mentoring of many residents and fellows and directing numerous (over 100) Harvard Medical School postgraduate courses. He has long had a strong interest in medical history and co-edited (2011) a book (with Dr. David N. Louis) on the history of pathology at the Massachusetts General Hospital and has edited for many years a series of essays on major figures in gynecologic pathology published in the International Journal of Gynecologic Pathology.
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Mass General Pathology
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Phone: 617-643-0800
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Dr. Young's research includes clinicopathological studies in gynecological and urological pathology. In gynecologic pathology, ovarian tumors in the categories of the sex cord-stromal tumors and metastatic neoplasms are of particular interest. Dr. Young has written papers on sex cord tumors that have helped define their morphologic spectrum and clinical behavior. He has also highlighted the propensity for mucinous tumors metastatic to the ovary to simulate primary mucinous cancers of the ovary, work that has been confirmed by other observers. Studies continue on the exploration of various aspects of the morphology of primary and metastatic ovarian neoplasms. In the area of uterine pathology, Dr. Young's special interests at this time include the morphology of unusual variants of endometrial cancer and of endometrial stromal tumors. Dr. Young has written extensively on both benign and malignant glandular lesions of the cervix and has defined several new entities whose recognition has very important clinical consequences with regard to therapy.
In urologic pathology, Dr. Young's major interests are in bladder and testicular tumor pathology. Dr. Young and fellow collaborators have highlighted deceptively benign patterns of bladder cancer that can cause them to be misinterpreted as benign lesions. In companion with that area of investigation he has explored the morphology of the converse problem, namely the misinterpretation of various benign lesions as cancer. In the area of testicular pathology work has included description of variant patterns of germ cell and sex cord stromal tumors.
For more information about research concepts, co-authors, and to see a timeline, visit Dr. Young's profile at the Harvard Clinical and Translational Science Center.
