About Sebastian Unizony, MD

Dr Unizony is the director of the Rheumatology Vasculitis Program. His main academic interests include the use of clinical and translational research methods to advance the treatment for patients with systemic vasculitides and related disorders, including giant cell arteritis, polymyalgia rheumatica and ANCA-associated vasculitis. He is a member of the Pan American League of Associations for Rheumatology (PANLAR) vasculitis group that has published treatment guidelines for giant cell arteritis, Takayasu’s arteritis and ANCA-associated vasculitis. A list of his publications can be found in the following link:

https://pubmed.ncbi.nlm.nih.gov/?term=Unizony+S&sort=date

Departments, Centers, & Programs:

Clinical Interests:

Treats:

Languages:

Locations

Mass General Rheumatology
55 Fruit St.
Yawkey Center for Outpatient Care
Suite 4B
Boston, MA 02114
Phone: 617-726-7938

Medical Education

  • MD, Universidad Nacional de La Plata
  • Residency, Hospital Carlos Durand
  • Residency, St. Luke's Roosevelt Hospital Center
  • Fellowship, Massachusetts General Hospital

American Board Certifications

  • Rheumatology, American Board of Internal Medicine

Note: This provider may accept more insurance plans than shown; please call the practice to find out if your plan is accepted.


Publications

  • Matza MA, Arevalo AB, Unizony S. Imaging Challenges and Developments in Large-vessel Vasculitis. Rheum Dis Clin North Am. 2024, PMID: 39415370

    Magri SJ, Ugarte-Gil MF, Brance ML, Flores-Su?rez LF, Fern?ndez-?vila DG, Scolnik M, Sato EI, de Souza AWS, Saldarriaga-Rivera LM, Babini AM, Zamora NV, Felquer MLA, Vergara F, Carlevaris L, Scarafia S, Guppy ERS, Unizony S; Pan American League of Associations for Rheumatology. Pan American League of Associations for Rheumatology Guidelines for the treatment of ANCA-associated vasculitis. Lancet Rheumatol. 2023 PMID: 38251580

    Unizony S, Matza MA, Jarvie A, O'Dea D, Fernandes AD, Stone JH. Treatment for giant cell arteritis with 8 weeks of prednisone in combination with tocilizumab: a single-arm, open-label, proof-of-concept study. Lancet Rheumatol. 2023, PMID: 38251564

    Spiera RF, Unizony S, Warrington KJ, Sloane J, Giannelou A, Nivens MC, Akinlade B, Wong W, Bhore R, Lin Y, Buttgereit F, Devauchelle-Pensec V, Rubbert-Roth A, Yancopoulos GD, Marrache F, Patel N, Dasgupta B; SAPHYR Investigators. Sarilumab for Relapse of Polymyalgia Rheumatica during Glucocorticoid Taper. N Engl J Med. 2023, PMID: 37792612 Clinical Trial.

    Matza MA, Dagincourt N, Mohan SV, Pavlov A, Han J, Stone JH, Unizony S. Outcomes during and after long-term tocilizumab treatment in patients with giant cell arteritis. RMD Open. 2023, PMID: 37024237

    Scolnik M, Brance ML, Fern?ndez-?vila DG, Inoue Sato E, de Souza AWS, Magri SJ, Saldarriaga-Rivera LM, Ugarte-Gil MF, Flores-Suarez LF, Babini A, Zamora NV, Acosta Felquer ML, Vergara F, Carlevaris L, Scarafia S, Soriano Guppy ER, Unizony S; Pan American League of Associations for Rheumatology (PANLAR). Pan American League of Associations for Rheumatology guidelines for the treatment of giant cell arteritis. Lancet Rheumatol. 2022, PMID: 38261393

    Cid MC*, Unizony S*, Blockmans D, Brouwer E, Dagna L, Dasgupta B, Hellmich B, Molloy E, Salvarani C, Trapnell BC, Warrington KJ, Wicks I, Samant M, Zhou T, Pupim L, Paolini JF; KPL-301-C001 Investigators. Efficacy and safety of mavrilimumab in giant cell arteritis: a phase 2, randomised, double-blind, placebo-controlled trial. Ann Rheum Dis. 2022, PMID: 35264321. * Co-first authors

    Unizony S, Bao M, Han J, Luder Y, Pavlov A, Stone JH. Treatment failure in giant cell arteritis. Ann Rheum Dis. 2021, PMID: 34049857

    Stone JH, Tuckwell K, Dimonaco S, Klearman M, Aringer M, Blockmans D, Brouwer E, Cid MC, Dasgupta B, Rech J, Salvarani C, Schett G, Schulze-Koops H, Spiera R, Unizony S, Collinson N. Trial of Tocilizumab in Giant-Cell Arteritis. N Engl J Med. 2017, PMID: 28745999

Reviews: Comments and Ratings

4.8out of 5(143 Ratings, 54 Comments)

May 2025

Dr Unizony is the best. He knows me, my history, remembers my issues. He is friendly and professional. I've been seeing him for 11 years, wouldn't see anyone else. Plus, a sense of humor!


April 2025

Dr. Unizony is tops in his field for the disease I have. We talked about clinical trials and I was able to get a ether understanding about my situation


April 2025

Excellent! Only concern, this was a consult for my regular rheumatologist. I do not see a write up or report for this visit. My Rheumatologist has not recieved any reoprt or write up. This info is needed.


April 2025

Nothing short of amazing for the last 13 yrs


April 2025

Yes, Dr. Unizony has always been extraordinarily thoughtful and informative and has taken care of me for the last two, three years I believe. And at all times he has been amazingly kind and full of information and has done all sorts of different tests. I couldn't recommend him more highly.


April 2025

Excellent provider. A fellow or resident first came in, but I told him I only wanted to deal with Dr. Unizony. That day i was definitely not in the mood to go through a lengthy assessment.


April 2025

Excellent. I have seen Dr. Unizony for years and he is always helpful, responsive and knowledgable.


March 2025

Thought it was a good visit


March 2025

Immediately after being diagnosed with Giant Cell Arteritis (GCA) in [redacted], I sought out Dr. Unizony, a leading researcher for treatment of GCA, for my treatment. I was quickly accepted into a clinical trial he was leading to test a new GCA treatment and received incredible attention and care. When my 12 months in the trial ended, Dr. Unizony ... Read More


March 2025

Excellent

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