Lecturer on Surgery (formerly the Helen Andrus Benedict Professor of Surgery and Bioengineering), Massachusetts General Hospital and Harvard Medical School
Director and Founding Director, Center for Engineering in Medicine & Surgery, Massachusetts General Hospital
Founding Co-Director, The Institute for Bioengineering and Biotechnology, a Division in Surgery at Mass General
About Dr. Yarmush
Professor Yarmush is the Founding Director of the Center for Engineering in Medicine & Surgery (CEMS). He is an internationally recognized expert in several areas of biotechnology and bioengineering including tissue engineering and regenerative medicine, applied immunology, biopreservation, genomics and proteomics technologies, metabolic engineering, and bioengineered microsystems and biomedical devices.
Over the last 30 years, Dr. Yarmush has published over 550 refereed journal articles, has mentored >69 graduate students and >120 postdoctoral fellows, and has taught a spectrum of courses from molecular genetics and immunology to thermodynamics and transport phenomena.
More than 70 of his former fellows have gone on to successful careers in academia both here and abroad, and many others have gone on to become leaders in the biotechnology and medical device industries. A frequent invited speaker at major conferences and institutions, and winner of over 30 local and national awards, Professor Yarmush’s investigative activities encompass both basic and applied research and have resulted in numerous patents and the formation of >10 start-up companies. He has also served as editor of several journals, most notably the Annual Review of Biomedical Engineering (ARBME), which has consistently been either number one or two in impact factor among its peer group of Biomedical Engineering journals.
The research activities in Professor Yarmush’s laboratory broadly address both scientific and engineering aspects of various challenging areas in biotechnology and clinical medicine.
Among his current projects are the following: new nanoparticle technology to enhance wound healing; microfabricated tissue-on-a-chip-systems for disease modeling and drug/environmental toxin testing; pulsed electric field techniques to promote scarless wound healing and wound disinfection; organ re-engineering through recellularization of decellularized scaffolds and revitalization perfusion of marginal organs; supercooling and partial freezing preservation of cells, tissues, and organs; encapsulated mesenchymal stem cells for treatment of spinal cord injury, osteoarthritis, and traumatic brain injury; and development of automated robotic venipuncture devices with point-of-care capabilities.
Success in tackling these projects is enabled using state-of-the-art techniques that include microfabrication and nanotechnology; physical biochemistry; genomics, proteomics and genetic engineering; cell biology and tissue engineering; advanced microscopic imaging; physiologic instrumentation; animal studies; and numerical simulation.
The Engineering Research Center established through a $26 million National Science Foundation award could prove to be a game-changer for transplantation, cellular therapies, and biodiversity.
Center for Engineering in Medicine & Surgery
A place where scientific rigor and creativity are matched by a sense of community, the Center for Engineering in Medicine & Surgery is a relatively young and vibrant enterprise that draws strength from its diversity and collective spirit, and from its affiliations with surrounding biomedical research institutions, including Massachusetts General Hospital, the Shriners Hospitals for Children and the Massachusetts Institute of Technology.