News & Events

Browse our interactive material, read recent ALS publications and news articles, or find information on our upcoming events.


Currently Browsing:2015

Currently Browsing:2014

Currently Browsing:2013

  • Strides in Understanding and Treating ALS

    Sunday, December 01, 2013  Mass General

    The Northeast ALS Consortium, co-founded by Massachusetts General Hospital researcher Merit Cudkowicz, MD, has spurred basic and translational research that has led to investigational therapies and improved patient outcomes.


Currently Browsing:2014

  • NeuroImage: Clinical

    Monday, December 22, 2014

    Evidence from human post mortem, in vivo and animal model studies implicates the neuroimmune system and activated microglia in the pathology of amyotrophic lateral sclerosis.

Currently Browsing:2013

  • The Lancet: Neurology

    Monday, September 23, 2013

    In a phase III trial, dexpramipexole was generally well tolerated but did not differ from placebo on any pre-specified efficacy endpoint measurement. The trial can inform the design of future clinical research strategies in amyotrophic lateral sclerosis.

Currently Browsing:2012

  • Stem Cells

    Tuesday, March 13, 2012

    The results of an ongoing Phase I trial of intraspinal injections of fetal-derived neural stems cells in patients with ALS.
  • Amyotrophic Lateral Sclerosis

    Wednesday, May 16, 2012

    Published Phase II results demonstrated that single oral doses of 250 mg and 500 mg of CK-2017357 appeared safe and well-tolerated in patients with ALS.
  • MIND Research Review

    Saturday, December 15, 2012

    A review of research at the Massgeneral Institute for Neurodegenerative Disease.

Currently Browsing:2011

  • Nature Medicine

    Sunday, November 20, 2011

    Phase II, two-part trial examining safety and tolerability of dexpramipexole in patients with ALS.

Currently Browsing:2010

  • Lancet Neurology

    Saturday, May 01, 2010

    Double-blind, placebo-controlled trial with a time-to-event design assessing the safety and efficacy of lithium in combination with riluzole in patients with ALS.
  • Therapy Times

    Sunday, May 23, 2010

    Paige Nalipinski, senior speech language pathologist and project coordinator at MGH, writes about ALS care guidelines and her experience working with patients at the MGH ALS Multidisciplinary Clinic.

Currently Browsing:2008

  • Muscle & Nerve

    Tuesday, July 01, 2008

    Safety, tolerability, and pharmacokinetics of arimoclomol in ALS were assessed.

Currently Browsing:2006

  • Annals of Neurology

    Saturday, July 01, 2006

    A double-blind, placebo-controlled, clinical trial to determine if celecoxib is safe and effective in ALS.

Currently Browsing:2005

  • Neurology

    Tuesday, December 13, 2005

    An open-label dose-escalation trial was performed to assess the safety and tolerability of high doses of coenzyme Q10 (CoQ10) in ALS.

Currently Browsing:2004

  • Neurology

    Tuesday, November 09, 2004

    A randomized double-blind, placebo controlled trial on 104 patients with ALS from 14 sites to evaluate the efficacy of creatine supplementation in ALS.

Currently Browsing:2003

  • Neurology

    Tuesday, August 26, 2003

    A double-blind, placebo-controlled, multicenter randomized clinical trial to determine if long-term topiramate therapy is safe and slows disease progression in patients with ALS.


Currently Browsing:2015

  • MGH ALS Symposium

    Saturday, May 09, 2015

    Please join us for an open exchange of data and ideas to help us succeed in our mission to find cures for ALS and provide excellence in care for people and their families with ALS.

Currently Browsing:2012


  • ALS slideshow

    ALS slideshow

    ALS slideshow

  • Ceftriaxone in ALS Webinar

    The Clinical Trial of Ceftriaxone in ALS

    A webinar recording explaining the design and scientific rationale behind the Clinical Trial of Ceftriaxone in Amyotrophic Lateral Sclerosis (ALS), commonly known as Lou Gehrig's disease.

  • Ceftriaxone in ALS Video

    Ceftriaxone Trial Video

    A video explaining the design and scientific rationale behind the Clinical Trial of Ceftriaxone in Amyotrophic Lateral Sclerosis (ALS), commonly known as Lou Gehrig's disease.

  • Neurology bicentennial logo

    Neurology Bicentennial Celebration, 2011 Part I

    Neurology Bicentennial Celebration, October 13, 2011. Past History of MGH Neurology; Overview of MGH Neurology; Telestroke and Acute Stroke Service; Neurodegenerative Disorders; Pediatric Neurology.

  • Neurology bicentennial logo

    Neurology Bicentennial Celebration, 2011 Part II

    Neurology Bicentennial Celebration, October 13, 2011. Clinical and research presentations on ALS, Stroke, Alzheimer’s Disease, and Parkinson’s Disease

  • respiratory assistance video

    Respiratory Assistance Video

    A video for ALS patients discussing and demonstrating uses of bipap and cough assist machines.

  • Welcome for Patients

    ALS Patient Video

    Nicole from Boston, shares her story about her battle with ALS and her strong desire to help others with the disease in the future. Mass General's ALS Multidisciplinary Clinic provides the latest treatments and research opportunities for people with Amyotrophic Lateral Sclerosis.

  • Dr. Cudkowicz

    Patient Welcome from Dr. Cudkowicz

    Dr. Merit Cudkowicz, Neurology's Chief of Service, shares what makes the Mass General ALS Multidisciplinary Clinic so special.

  • Dr. Merit Cudkowicz, recipient of MDA LOU GEHRIG HUMANITARIAN AWARD

    Congratulations to Dr. Merit Cudkowicz for receiving the MDA LOU GEHRIG HUMANITARIAN AWARD

    Congratulations to Dr. Merit Cudkowicz, MGH Neurology Department Chairperson and Director, MGH ALS Clinic, for receiving the MDA LOU GEHRIG HUMANITARIAN AWARD. This award is given to a researcher, physician, or clinician who supports MDA/ALS research initiatives and clinical services and continues to fight the battle against ALS. View her acceptance speech where she discusses reasons for hope in the future of ALS treatments.

  • ALS Walk of Hope

    ALS Walk of Hope

    Learn how the Walk of Hope, sponsored by the ALS Raising Hope Foundation ( raises funds for neurodegenerative disease research at MIND-and how researchers are using it to find cures.

  • Help us find a cure for ALS

    Learn why MGH ALS researchers have hope for a cure and the research they are undertaking to find it.

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