Dr. Brian Nahed is a neurosurgeon who specializes in Brain Tumors (Glioblastoma, Gliomas, Meningiomas, Metastatic Brain Tumors) and Spinal Disorders. He is Assistant Professor in the Department of Neurosurgery and Pappas Center for Neurooncology.
BiographyDr. Brian Nahed is a neurosurgeon who specializes in brain tumors (glioblastoma, gliomas (low grade and high grade), metastatic brain tumors, and meningiomas) as well as Spinal Disorders. Dr. Nahed's clinic interest are in tumors of the eloquent cortex requiring awake surgery, language and motor mapping, and subcortical stimulation.
Born in New York, Dr. Nahed attended UCLA where he majored in Neuroscience, graduating Phi Beta Kappa and with the department's Highest Honors. He attended the Yale School of Medicine where he was awarded the Doris Duke Clinical Research Fellowship and graduated with honors. Dr. Nahed completed his internship and neurosurgery residency at the Massachusetts General Hospital; where Dr. Nahed also completed a postdoctoral fellowship with Drs. Daniel Haber and Shyamala Maheswaran in the MGH Cancer Center.
Dr. Brian Nahed was recruited to the MGH Department of Neurosurgery and Brain Tumor Center in 2011. As an assistant professor of Harvard Medical School, Dr. Brian Nahed's research focuses on developing the first blood based test to diagnose and monitor brain tumors. In collaboration with Drs. Haber, Maheswaran, and Stott, Dr. Nahed recently published the first evidence of circulating tumor cells in the blood patients with glioblastoma. Dr. Nahed is actively enrolling patients into his translational clinical research study.
Dr. Brian Nahed is an active member of the American Association of Neurological Surgeons, Congress of Neurological Surgeons, and the Joint section on Tumors. In addition, he serves as chairman of the education and communication committee for the Council State Neurological Societies. Dr. Nahed also is a member of the Joint Section on Tumors for the CNS/AANS. Dr. Nahed is focused on education and socioeconomic issues in neurosurgery and training. He also serves as a neurotrauma consultant for the National Football League (NFL).
Circulating Brain Tumor Cells
Metastatic Diseases of the Brain
Dr. Brian Nahed's research recently identified the first evidence of tumor cells in the blood of patients with brain tumors - a landmark finding which changes our understanding of brain tumors and the blood. Dr. Brian Nahed and his colleagues developed the first device which they used to identify, capture, and analyze circulating tumor cells in the blood of patients with brain cancer. Through a collaboration between bioengineers, molecular biologists and clinicians, a circulating tumor cell capture device was developed to capture and detect tumor cells from patients with cancer. Under the mentorship of Drs. Daniel Haber, Shyamala Maheswaran, and Mehmet Toner, they aim to harness this technology to genetically characterize tumor cells without needing an invasive biopsy, and determine responsiveness to targeted cancer drugs. It also offers the opportunity to study cancer stem cells or metastasic precursors, thought to be at the origin of cancer spread via the bloodstream, to define their molecular vulnerabilities and help design new therapies to prevent cancer metastasis. Dr. Nahed has joined Dr. Shannon Stott to develop the first clinical tool to identify and monitor brain tumor patients using a blood test - expanding on their individual work on circulating tumor cells and exosomes.
Dr. Nahed's research was recently published in Cancer Discovery and he is active enrolling patients in his translational clinical research study. More information about his research lab can found at the the Nahed Brain Tumor Research Lab.
89 peer-reviewed publications which can be found on pubmed for a complete list of the publications.
Dr. Brian Nahed's research project focuses on developing a blood based test to diagnose and monitor brain tumors. More information about his research lab can be found at the Nahed Brain Tumor Research Lab Website.
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