About half of a small group of patients with fibromyalgia – a common syndrome that causes chronic pain and other symptoms – was found to have damage to nerve fibers in their skin and other evidence of a disease called small-fiber polyneuropathy, a disorder that sometimes can be treated. Read more.
Photo Credit: PAIN/doi/10.1016/j.pain.2013.06.001
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12/06/13: Clinical waste may prove valuable for monitoring treatment response in ovarian cancer MGH investigators have developed a microchip-based device that can isolate and identify tumor cells found in ascites – an accumulation of fluid in the abdomen that often occurs in abdominal cancers – potentially simplifying the monitoring of treatment response in ovarian cancer and other malignancies.
11/28/13: Researchers find a missing component in effort to create primitive, synthetic cells A team of MGH investigators working to create "protocells" – primitive synthetic cells consisting of a nucleic acid strand encased within a membrane-bound compartment – have accomplished an important step towards their goal, finding a solution to the potential incompatibility between a chemical requirement of RNA copying and the stability of the protocell membrane.
11/24/13: Study identifies protein essential for innate immune recognition, response to viral infection An MGH research team has identified an immune cell protein that is critical to setting off the body's initial response against viral infection. The report describes finding that a protein called GEF-H1 is essential to the ability of macrophages – major contributors to the innate immune system – to respond to viral infections.
11/20/13: Current practice may over-diagnose vitamin D deficiency The current "gold standard" test for measuring vitamin D status may not accurately diagnose vitamin D deficiency in black individuals. The findings may explain the discrepancy between the prevalence of diagnosed vitamin D deficiency in black Americans and a lack of the usual symptoms of vitamin deficiency.
11/20/13: Study reveals how variant forms of APOE protein impact risk of Alzheimer's disease A study led by MGH investigators shows that even low levels of the Alzheimer's-associated APOE4 protein can increase toxic amyloid beta brain plaques and the characteristic neuronal damage in mouse models of the disease. Introducing APOE2, a rare, potentially protective variant, reduced amyloid deposits and the associated damage.
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12/08/2013: MGH docs return from Philippine typhoon zone
quotes MGH physicians Miriam Aschkenasy and Carmela Berlin, nurse Curt Audin
12/08/2013: Get a piece of Papi
(scroll down) – Boston Herald
item on auction benefiting MGHfC
12/07/2013: Her 4-year-old won't eat
blog entry includes recommendations from MGH physician Ronald Kleinman
12/06/2013: UMass Memorial study finds telemedicine improved ICU care
White Coat Notes/Boston.com
quotes MGH physician Lee Schwamm
12/06/2013: Mass. company offers visits with primary care doctors via smartphone, tablet, computer
White Coat Notes/Boston.com
quotes MGH physician Allan Goroll