Massachusetts General Hospital (MGH) investigators have determined that one of the recently identified genes contributing to the risk of late-onset Alzheimer's disease regulates the clearance of the toxic amyloid beta (A-beta) protein that accumulates in the brains of patients with the disease. In their report receiving advance online publication in Neuron, the researchers describe a protective variant of the CD33 gene that promotes clearance of A-beta from the brain. They also show that reducing expression of CD33 in immune cells called microglia enhances their ability to clear away A-beta protein, raising the possibility that blocking CD33 activity could help the brain’s immune system remove A-beta. Read more.
Services for the Media
5/22/2013: Survey points out deficiencies in addictions training for medical residents A 2012 survey of internal medicine residents at Massachusetts General Hospital found that more than half rated the training they had received in addiction and other substance use disorders as fair or poor. In response to the findings the MGH has increased residents' training in addiction medicine.
5/20/13: Genetic diversity within tumors predicts outcome in head and neck cancer A new measure of the heterogeneity – the variety of genetic mutations – of cells within a tumor appears to predict treatment outcomes of patients with the most common type of head and neck cancer.
5/15/13: Study finds disagreement on the role of primary care nurse practitioners A New England Journal of Medicine study finds that, while primary care physicians and nurse practitioners agree that nurse practitioners "should be able to practice to the full extent of their education and training," they significantly disagree about some proposed changes to the scope of nurse practitioners' responsibilities.
5/14/13: Treatment with two osteoporosis drugs better at increasing bone density than single-drug therapy A combination of two FDA-approved osteoporosis drugs with different mechanisms of action was found to increase bone density better than treatment with either drug alone in a small clinical trial.
5/13/13: Massachusetts General Hospital Receives Highest Nursing Credential With Prestigious Magnet® Recognition … Again The Massachusetts General Hospital has again attained Magnet® recognition as part of the American Nurses Credentialing Center’s Magnet Recognition Program®. This voluntary credentialing program recognizes excellence in nursing and is the highest honor an organization can receive for professional nursing practice.
Newsletters & Publications
Hotline Each week, MGH Hotline reports important news within the Massachusetts General Hospital community featuring employees and initiatives that focus on bettering the future of clinical care, research and training.
Proto Proto, a magazine that reaches 75,000 thought leaders nationwide, stakes its ground on medicine's leading edge, reporting back from the frontiers of research and practice—exploring breakthroughs, dissecting controversies and opening a forum for informed debate.
Mass General Magazine Mass General Magazine takes you into the heart of the institution, describing ways in which Mass General is leading the way in educating physicians, nurses and other healthcare professionals; in improving the health of local and distant communities; and in establishing best practices and health policy.
05/22/2013: ADHD in Preschoolers?
quotes MGH physician James Perrin
05/22/2013: For heart health, avoid angry response to this blog
blog entry by MGH physician Suzanne Koven
05/22/2013: Even At Mass. General, Medical Training On Addiction Deemed Lousy
coverage of study led by MGH chief resident Sarah Wakeman
05/22/2013: Health Policy Commission to review Partners HealthCare plan to acquire South Shore Hospital
White Coat Notes/Boston.com
05/22/2013: Braintree cop Timulty invited to run again in Boston Marathon
article on participant in MGH Marathon Team
05/22/2013: Aylesbury’s Alex feeling fit and strong after first rounds of therapy
Thame Today (U.K.)
includes photo of patient being treated at MGH Proton Therapy Center