Adult Kidney Transplant Program

The Adult Kidney Transplant Program at Massachusetts General Hospital provides individualized, ongoing care for patients with end-stage renal disease (kidney failure).

A pioneer in organ transplant since 1963, the Adult Kidney Transplant Program at the Massachusetts General Hospital Transplant Center draws from state-of-the-art technology and leading-edge medical and surgical interventions to provide individualized, ongoing care for patients with chronic kidney disease. Our expert surgeons have performed more than 1,700 kidney transplants, and have achieved some of the best graft and patient survival rates in the country.
Kidney transplant patients typically require lifelong immunosuppressive medications to prevent their immune systems from attacking the new organ. However, our ground-breaking research is allowing some patients to live drug-free after transplant. We also offer options for highly sensitized patients, patients with incompatible living donors, and patients with challenging medical or surgical issues.
Leadership in Kidney Transplantation

We have consistently led the field in tolerance or the acceptance of transplanted organs without long-term immunosuppression. We performed the first successful tolerance induction for renal allografts in patients with multiple myeloma in 1998. We initiated the first ITN-sponsored clinical tolerance trials for adults in 2001, and performed the first successful tolerance induction in mismatched renal transplant recipients in 2008.
Advanced Evaluation, Multidisciplinary CareAll our patients receive integrated, comprehensive care to treat chronic renal failure, beginning with a careful assessment and discussion with the patient to ensure that transplantation is his/her best treatment option. Candidates work with a transplant coordinator, who participates in the initial evaluation, gathers medical information and previous test results. The transplant coordinator also manages the patient’s full evaluation, which includes patient education, medical, surgical and psychosocial evaluation, and transplant-specific testing. Learn more about the pre-transplant evaluation

Kidney transplant candidates are placed on the national United Network for Organ Sharing (UNOS) waiting list, which manages the distribution of organs nationwide. Learn more about the waiting list

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Support us

To learn more how you can support the Kidney Transplant Program, contact James F. Markmann, MD, PhD, at 617-643-4533

To make a gift now, please contact Tyrone C. Latin in Mass General Development at 617-643-5781 or make a donation online

Living Donor Kidney Transplant Programs

Patients who choose to undergo a kidney transplant may have identified a living donor who is willing to donate a kidney. Even in cases where the donor is incompatible with the recipient, our active living donor transplant program can match patients with compatible living donors through the UNOS Paired Kidney Exchange Program or the National Kidney Registry. We also have a successful desensitization program for patients with positive cross match to their living donors and a protocol for ABO-incompatible donor-recipient pairs. Learn more about programs for patients with incompatible living donors
Living Donor Evaluation Those interested in living kidney donation can contact our donor coordinator for a confidential conversation to learn more, without any commitment to donation. Medical, surgical and psychosocial evaluation begins only after a prospective donor is fully educated and has consented to donate, and candidates may withdraw from the donation process at any time. Learn more about the donor evaluation
Post-transplant CareAfter transplantation, patients are followed by our team of surgeons, nephrologists and nurses who manage the post-transplant needs of the patient, including communication with the patient’s primary care physicians and referral to other specialists, as needed. Learn more about post-transplant care
Meet the TeamThe Mass General Kidney Transplant Team guides patients through every stage of care with a multidisciplinary team of doctors, nurses, dietitians, case managers, financial coordinators and other clinicians to help navigate the transplant process. Scroll through the list below to meet the team. Learn more about the Kidney Transplant Team


Explore transplant clinical trials

Learn more about leading-edge therapies and clinical trials offered through our kidney and islet transplant programs.

Refer a patient to the Transplant Center

Request an appointment for your patient with one of our world-class transplant specialists.

Download our patient guide to transplantation

View the Transplant Center’s patient guide for information about transplantation, including how to prepare for surgery and how to care for your new organ.