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A pioneer in organ transplantation since 1963, Massachusetts General Hospital offers patients both well-established and leading-edge treatment options for chronic kidney disease and type 1 diabetes.Our groundbreaking work in tolerance induction for kidney transplant recipients has allowed patients to live drug-free after their transplantations. Our patients also have access to the latest clinical trials as our dedicated researchers continue to turn laboratory breakthroughs into improvements in patient care. Learn about our programs:
The links below provide more information about conditions and diseases that might be treated within this program.
Analgesic nephropathy is a chronic kidney disease that gradually leads to end-stage renal disease and the need for permanent dialysis or a kidney transplant.
Biliary cirrhosis is a rare form of liver cirrhosis, caused by disease or defects of the bile ducts.
Type 1 diabetes may also be known by a variety of other names, including the following: insulin-dependent diabetes mellitus (IDDM), juvenile diabetes, brittle diabetes, or sugar diabetes.
Nephropathy is the deterioration of the kidneys. The final stage of nephropathy is called end-stage renal disease, or ESRD.
Renal failure refers to temporary or permanent damage to the kidneys that results in loss of normal kidney function.
Glomerulonephritis is a type of glomerular kidney disease in which the kidneys' filters become inflamed and scarred, and slowly lose their ability to remove wastes and excess fluid from the blood to make urine.
Glomerulosclerosis is the term used to describe scarring that occurs within the kidneys in the small balls of tiny blood vessels called the glomeruli.
Goodpasture syndrome is a rare, autoimmune disease that can affect the lungs and kidneys.
Hematuria is the presence of red blood cells (RBCs) in the urine.
Hemolytic uremic syndrome is a rare condition that mostly affects children under the age of 10. It is often characterized by damage to the lining of blood vessel walls, destruction of red blood cells, and kidney failure.
Underactive parathyroid glands do not produce enough parathyroid hormones. This causes low levels of calcium in the blood.
IgA nephropathy is a chronic kidney disease that may progress over a period of 10 to 20 years, and can lead to end-stage renal disease.
Nephrotic syndrome is a condition often characterized by the following: very high levels of protein in the urine, low levels of protein in the blood, swelling, especially around the eyes, feet, and hands, as well as
Pancreatic cancer is the fourth most common cause of cancer death in men and women in the US. Pancreatic cancer occurs when malignant cells grow out of control.
Polycystic kidney disease (PKD) is a genetic disorder characterized by the growth of numerous cysts filled with fluid in the kidneys.
Renal vascular disease is the name given to a variety of complications that affect the arteries and veins of the kidneys.
Mass General is dedicated to ensuring that people understand their health care choices and have the necessary information to make decisions affecting their health and well being. The related support and wellness information listed below can play a role in treatment options.
Read the Transplant Center's award-winning patient education guide, Transplantation: What Do I Need to Know?
John Marzelli and Esperanza Yoblonsky were suffering from IgA nephropathy and both needed a new kidney; they found the answer in the Mass General Transplant Center’s internal exchange program.
Toddler Andrew Johnson is thriving since receiving his mother’s kidney in a transplant at MassGeneral Hospital for Children.
MGH Hotline 4.15.11 When 35-year-old Eric Walker was diagnosed with kidney failure in 2006, the life of the once energetic husband and father of three young children changed completely.
When 14-year-old Kassie Holmes was faced with going back on dialysis or receiving a kidney transplant, Avram Traum, MD, recommended a transplant regiment that did not include steroids.
The Department of Health and Human Services awarded the Transplant Center a Medal of Honor for its outstanding achievements in organ donation, including a donation rate of 75 percent or more eligible donors.
Our physicians discuss the education, management and prevention of diabetes, a condition affecting nearly 24 million adults and children in the United States.
Clinicians at the Transplant Center received a National Health Information Award for developing an outstanding patient education book and streamlining the patient evaluation process.
Seven years after undergoing a groundbreaking transplant procedure developed at Massachusetts General Hospital, Jennifer Searl competes in her third World Transplant Games in Australia.
The Transplant Center celebrated Donate Life Month by raising public awareness about the importance of organ donation and also extending thanks to the many organ donors and families who have given the generous gift of life to others.
Eight years ago, Jennifer Searl used a handicapped permit to get around campus at the University of New Hampshire. Last October, Searl, 26, ran a half-marathon and felt so good afterward she immediately signed up for another. In between these two extremes lies not only a journey of a thousand steps, but one taken along a path Searl herself blazed - with help from the Massachusetts General Hospital Transplant Center.
At the Transplant Center, clinicians and scientists work side by side to develop innovative therapies that have revolutionized transplant medicine around the globe. These dynamic interactions are a unique strength of the center, leading to a number of groundbreaking "firsts" that continue to improve the lives of patients.
When Massachusetts General Hospital gave Jennifer Searl the world’s first non-HLA-matched combined kidney and bone marrow transplant in 2002, it was more than just a scientific breakthrough. For Searl, it was the beginning of a new life.
Kidney/Pancreas/Islet Transplant Programs
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