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Pediatric Endocrine Program and Diabetes Center

The Pediatric Endocrinology Program and Diabetes Center at MassGeneral Hospital for Children is an international referral center for the management of pediatric diabetes and endocrine disorders in children and adolescents.

Contact the Pediatric Endocrine Program and Diabetes Center: 617-726-2909

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Overview

The Pediatric Endocrinology Program and Diabetes Center at MassGeneral Hospital for Children is an international referral center for the management of pediatric diabetes and endocrine disorders in children and adolescents. Every patient of the Pediatric Endocrine Unit has a personal endocrinologist. We work collaboratively with primary care physicians, other specialty caregivers, and–most importantly– patients and their families to deliver the highest quality of care.

Our physicians specialize in the diagnosis and treatment of all endocrine-related conditions of infants, children and adolescents, including:

  • Diabetes mellitus type 1
  • Diabetes mellitus type 2
  • Growth disorders
  • Thyroid and adrenal problems
  • Problems of puberty
  • Hypoglycemia
  • Pituitary disorders, including pituitary tumors, hormone deficiencies, diabetes insipidus, and care of patients following therapy of brain tumors
  • Calcium and bone metabolism disorders, including rickets, osteoporosis, osteogenesis imperfecta, and parathyroid disease
  • Disorders of sexual development
  • Hirsutism and menstrual disorders, including polycystic ovarian syndrome
  • Endocrine tumors

Special areas of excellence within pediatric endocrinology include:

The Pediatric Diabetes Center: We provide comprehensive care to children and adolescents with both type 1 (juvenile-onset; insulin-dependent) and type 2 (adult-onset; non-insulin-dependent) diabetes mellitus. The Diabetes Center offers an individualized approach to each child with diabetes and to the family. The team of diabetes specialists includes pediatric endocrine and diabetes physicians, nurses, nurse practitioners, dieticians and social workers, all with years of experience working with children and adolescents with diabetes. Our nurses and nurse practitioners are Certified Diabetes Educators (CDEs), just one indication of their commitment to high quality care. The education program is certified by the American Diabetes Association. We provide coordinated outpatient care from diagnosis through chronic management. We are a leading center for outpatient management of newly diagnosed diabetes.

Type 1 Diabetes: Of the hundreds of adolescents and children with diabetes for whom we provide specialty care, half receive their daily insulin needs via insulin pump, which permits a high degree of flexibility but which also mandates intensive monitoring. Many young people also use a continuous glucose monitoring system. The insulin pump is not the best choice of all children with type 1 diabetes. However, our commitment to every family is the same: to achieve the best level of blood sugar control possible for each child we follow.

Children with type 1 diabetes may have other disorders including thyroid disease and celiac disease. Our endocrinology, gastroenterology and nutrition staff work together to integrate the management of these disorders. Our commitment to diabetes care also extends to the laboratory, where members of the pediatric endocrinology group are working to determine the protein factors in cells that control the development of the insulin producing beta cell with the aim of developing a means to reproduce beta cell function. We also collaborate with the diabetes immunology laboratory on clinical and laboratory studies to understand the cause of type 1 diabetes and its treatment. We are involved in international collaborative treatment studies to prolong the remission phase of type 1 diabetes, and we are working with bioengineers who are developing a "closed loop" system to measure blood sugar and replace insulin as it is needed. 

Type 2 Diabetes: We have the same commitment to personalized, multidisciplinary care of patients with type 2 diabetes, which is increasingly common among children and adolescents. We work with our Pediatric Weight Center to help children with type 2 diabetes and metabolic syndrome achieve optimal health. One reflection of that commitment is our active involvement in a nationwide research program designed to optimize care of young patients with this disorder (read about the TODAY Study).

Growth Disorders: John Crawford, MD, Chief of the Pediatric Endocrine Unit from 1963 to 1990, was among the first physicians in the world to treat children with growth failure with human growth hormone. The unit remains dedicated to offering patients with growth disorders state-of-the-art evaluation and therapy. This includes opportunities for selected patients to participate in clinical trials.

Neuroendocrinology: The Neuroendocrine Service works closely with neurosurgery and neuroradiology to assure up-to-date diagnostic studies and treatment for children with various pituitary disorders, including Cushing’s disease, acromegaly and disorders of growth related to pituitary disorders.

  • Children with pituitary disorders requiring surgery are managed in collaboration with neurosurgeons internationally recognized for transphenoidal pituitary surgery as well as open surgery when necessary.
  • Children with pituitary disorders requiring radiation receive treatment at the Francis H. Burr Proton Therapy Center at Massachusetts General Hospital, one of the few such facilities in the world.

Disorders of Puberty: We have particular expertise in caring for children with reproductive endocrine disorders and work closely with the adult Reproductive Endocrine Unit. The Reproductive Endocrine Service provides support for children and adolescents with disorders of puberty including precocious and delayed puberty, and abnormalities of pubertal development hirsutism and polycystic ovarian disease. This service was one of the first to offer effective treatment to children with sexual precocity.

Thyroid Disorders: Childhood thyroid disorders are managed through our general thyroid imaging and treatment unit. We offer comprehensive care and follow up of childhood thyroid cancer.

Disorders of Sexual Development: We provide medical, psychological and surgical support in an empathic and comprehensive manner for children born with incomplete genital or sexual development, chromosomal problems like Turner syndrome and Klinefelter syndrome, and adrenal disorders leading to genital abnormalities.

Disorders of Calcium and Bone Metabolism: Our staff is nationally known for expertise in the field of calcium, vitamin D and bone metabolism. We provide state-of –the-art interpretation of bone density tests in children and teenagers, and a comprehensive discussion of strategies to improve bone density in a variety of conditions. We work closely with our colleagues in Pediatric Nephrology to provide expertise in rare disorders of calcium and phosphate metabolism. Learn more about the Pediatric Bone and Mineral Metabolism Disorders Clinic.

At MassGeneral Hospital for Children, we know that the time of your child’s diagnosis and treatment is a very stressful one and we strive to provide an open, welcoming environment. We believe that no one knows a child as well as the parent does; parents, along with primary care providers, become our partners in a child's care and have an active voice in all treatment plans.

Meet the Team

Chief, Division of Pediatric Endocrinology

Our Providers

Fellows

  • Laurie Braun, MD
  • Laya Ekhlaspour, MD
  • Rabab Jafri, MD
  • Dayna McGill, MD
  • Jasreena Nijjar, MD
  • Shylaja Srinivasan, MD

Psychologist

Certified Diabetes Educators

Nutritionists

Social Workers

Medical Assistants

  • Stephanie Anastal
  • Katrina Brown
  • Nicole Mizzoni

Education

Pediatric Endocrinology Fellowship
The Pediatric Endocrinology Fellowship Program at MassGeneral Hospital for Children spans three years of training and prepares our fellows for careers as leaders in academic medicine and also clinical practice. Learn more.

Research

Pediatric Endocrine-Neuroendocrine-Sports Endocrine Research
Research within the Pediatric Endocrine-Neuroendocrine-Sports Endocrine Lab aims to further medical knowledge about common endocrine issues in athletes and girls with low-weight eating disorders. In particular, we focus our efforts on establishing findings that lead to the adaptation and improvement of medical care for female athletes and young girls and women with eating disorders. Learn more.

Pediatric Endocrinology Research Lab 
The goal of our laboratory research is to find ways to generate regulated insulin secretion in cells or tissues for pancreatic b-cell replacement therapy in diabetes. Learn more.

Patient Resources

News

  • Estrogen Replacement in Anorexia Nervosa - 1/1/2016, Mass General

    New research from MassGeneral Hospital for Children shows the benefits of estrogen replacement therapy for improving physiological and psychological outcomes in young females with anorexia nervosa.

  • Misra Elected to Board of Directors of Pediatric Endocrine Society - 12/3/2015, Mass General

    Madhusmita Misra, MD, MPH, chief of Pediatric Endocrinology at MGHfC, has been elected to serve on the Board of Directors of the Pediatric Endocrine Society from 2016-2016.

  • Understanding healthy bone growth in childhood to improve long-term quality of life - 4/29/2014, Research

    Childhood is a critical time for bone health. Approximately 90% of peak bone mass is acquired by age 18, with about 50% of this acquired during the pubertal growth spurt. As a pediatrician, my research goal is to better understand the factors which impact bone growth and mineralization during this important window in order to maximize long-term bone health.

  • Immune Therapy in Type 1 Diabetes - 12/20/2011, Research

    Dr. Sherry's focus is to develop a better understanding of type 1 diabetes by conducting current trials in immune therapy for type 1 diabetes (TIDM) and leading the development of new approaches to clinical trials in this field.

Contact

Contact Us

MGHfC Pediatric Endocrine Program & Diabetes Center

Yawkey Center for Outpatient Care

Suite 6C55 Fruit Street Boston, MA 02114
  • Near Public Transit
  • Handicapped Accessible
  • Phone: 617-726-2909
  • Fax: 617-724-0581

Hours

  • Monday through Friday, 8:30am-5:00pm

To schedule an appointment with a MassGeneral for Children pediatric specialist, please call 888-644-3248 or complete our online appointment form to request an appointment.

Physicians may call 888-644-3211 or use the online referral form and the Access & New Appointment Center will call your patient within 1 business day.

Contact the Pediatric Endocrine Program and Diabetes Center: 617-726-2909

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