The Pediatric Neuroendocrine Service works closely with neurosurgery, neuroradiology and radiation oncology to assure up-to-date diagnostic studies and treatment for children with craniopharyngiomas, Rathke Cleft cysts, and various pituitary tumors. We also manage conditions of pituitary hormone excess (such as hyperprolactinemia, Cushing’s disease, gigantism and acromegaly), pituitary hormone deficiency (such as growth hormone deficiency, central hypothyroidism, central hypoadrenalism, hypogonadotropic hypogonadism, and diabetes insipidus), and disorders of growth and puberty related to pituitary disorders.

Children with pituitary disorders requiring surgery are managed in collaboration with neurosurgeons internationally recognized for transsphenoidal pituitary surgery as well as open surgery when necessary.

Children with pituitary disorders requiring radiation receive treatment at the Francis H. Burr Proton Therapy Center at Massachusetts General Hospital, one of the few such facilities in the world.

Conditions We Treat

  • Pituitary hormone deficiencies
  • Pituitary hormone excess
    • Hyperprolactinemia
    • Cushing’s syndrome
    • Growth hormone excess (gigantism/acromegaly)
    • Other rare conditions of hormone excess
  • Pituitary tumors
    • Prolactinomas
    • Tumors secreting ACTH (corticotropinomas)
    • Tumor secreting growth hormone (somatropinomas)
    • Tumors secreting TSH (thyrotropinomas)
    • Non-secreting adenomas
  • Craniopharyngioma
  • Rathke Cleft cysts, pars intermedia cysts
  • Others
    • Multiple endocrine neoplasia type 1 and type 2
    • Pancreatic neuroendocrine tumors