About Brian Nahed, MD

Watch a video about my work

Clinical Interests:

Treats:

Locations

Mass General Cancer Center: Neuro-Oncology
55 Fruit St.
Yawkey Center for Outpatient Care
Boston, MA 02114
Phone: 617-724-5805
Fax: 617-724-5806

Medical Education

  • MD, Yale University School of Medicine
  • Residency, Massachusetts General Hospital
  • Residency, Massachusetts General Hospital
  • Fellowship, New England Baptist Hospital

American Board Certifications

  • Neurological Surgery, American Board of Neurological Surgery

Note: This provider may accept more insurance plans than shown; please call the practice to find out if your plan is accepted.


Research

Circulating Tumor Cells in Brain Tumor Patients and Blood Based Biomarkers for Brain Tumor Patients

Dr. Brian Nahed's research recently identified the first evidence of tumor cells in the blood of patients with brain tumors - a landmark finding which changes our understanding of brain tumors and the blood. Dr. Nahed and his colleagues developed the first device which they used to identify, capture, and analyze circulating tumor cells in the blood of patients with brain cancer. Through a collaboration between bioengineers, molecular biologists and clinicians, a circulating tumor cell capture device was developed to capture and detect tumor cells from patients with cancer. Under the mentorship of Drs. Daniel Haber, Shyamala Maheswaran, and Mehmet Toner, they aim to harness this technology to genetically characterize tumor cells without needing an invasive biopsy, and determine responsiveness to targeted cancer drugs. It also offers the opportunity to study cancer stem cells or metastatic precursors, thought to be at the origin of cancer spread via the bloodstream, to define their molecular vulnerabilities and help design new therapies to prevent cancer metastasis.

Dr. Nahed has joined Dr. Shannon Stott to develop the first clinical tool to identify and monitor brain tumor patients using a blood test - expanding on their individual work on circulating tumor cells and exosomes. They are actively enrolling patients into their NIH funded research program.  

For more information, please click here

Publications

  • Peer-Reviewed Publications: Dr. Nahed has 203 publications in peer-reviewed journals, given hundreds of presentations, published book chapters, and scientific and patient centered blogs. Please refer to PubMed for a complete list of Dr. Nahed's publications. Leader in Liquid Biopsy Research and the first to develop a blood test for patients with brain tumors. Dr. Brian Nahed and Dr. Shannon Stott have developed the first blood-based test to diagnose brain tumors from patient's blood. They have been awarded several grants, including an R01 from the NIH (National Institutes for Health) to develop a liquid biopsy for patients with brain tumors. Congress of Neurological Surgeons. Dr. Nahed serves on the Executive Committee of the Congress of Neurological Surgeons where he focuses on improving the education of neurosurgeons nationally and internationally. Dr. Nahed co-chairs the CNS leadership institute and serves as the co-chair of the development committee. He has served as scientific programming and annual meeting chair. Digital Biomarkers for Health. Dr. Nahed has developed novel use of digital biomarkers, technology, and tele-health to advance health care. Click Here

Reviews: Comments and Ratings

4.8out of 5(105 Ratings, 49 Comments)

June 2025

The provider was very helpful [redacted]


June 2025

i appreciated his plans for continued monitoring, [redacted]


June 2025

Dr Brian Nahed has been my Dr for 4 years and has been amazing! Always available, knowledgeable, kind , understanding , I cannot say enough about him!


June 2025

Dr. Nahed is an excellent provider - professional, compassionate and reviews with patience all information answering questions thoroughly touching base during all explanations to insure patient understanding. His expertise is amazing and the care he provides unparalleled. I am so grateful to be one of Dr. Nahed's patients.


June 2025

Meeting was Virtual. Dr. Nahed has a remarkable way of weaving together all the important clinical info into a decision with the patient. And does it in a genuine way that takes into account what the patient wants. Answers all questions and it never feels rushed though I know he is incredibly busy. I have not needed surgery yet (and hoping I do ... Read More


June 2025

He provided information that I could understand and was attentive.


May 2025

Dr, Nahed was very knowledgeable and most professional.


May 2025

He was very good.


May 2025

I thought Dr. Nahed was very kind in addition to being knowledgeable, comma, and he did not seem rushed while he was explaining what was going on, period.


May 2025

Dr Nahed is knowledgeable and a very effective communicator. We agreed upon a treatment plan that I am very comfortable with.

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