About Sebastian Unizony, MD

Dr Unizony is the director of the Rheumatology Vasculitis Program. His main academic interests include the use of clinical and translational research methods to advance the treatment for patients with systemic vasculitides and related disorders, including giant cell arteritis, polymyalgia rheumatica and ANCA-associated vasculitis. He is a member of the Pan American League of Associations for Rheumatology (PANLAR) vasculitis group that has published treatment guidelines for giant cell arteritis, Takayasu’s arteritis and ANCA-associated vasculitis. A list of his publications can be found in the following link:

https://pubmed.ncbi.nlm.nih.gov/?term=Unizony+S&sort=date

Departments, Centers, & Programs:

Clinical Interests:

Treats:

Languages:

Locations

Mass General Rheumatology
55 Fruit St.
Yawkey Center for Outpatient Care
Suite 4B
Boston, MA 02114
Phone: 617-726-7938

Medical Education

  • MD, Universidad Nacional de La Plata
  • Residency, Hospital Carlos Durand
  • Residency, St. Luke's Roosevelt Hospital Center
  • Fellowship, Massachusetts General Hospital

American Board Certifications

  • Rheumatology, American Board of Internal Medicine

Note: This provider may accept more insurance plans than shown; please call the practice to find out if your plan is accepted.


Publications

  • Matza MA, Arevalo AB, Unizony S. Imaging Challenges and Developments in Large-vessel Vasculitis. Rheum Dis Clin North Am. 2024, PMID: 39415370

    Magri SJ, Ugarte-Gil MF, Brance ML, Flores-Su?rez LF, Fern?ndez-?vila DG, Scolnik M, Sato EI, de Souza AWS, Saldarriaga-Rivera LM, Babini AM, Zamora NV, Felquer MLA, Vergara F, Carlevaris L, Scarafia S, Guppy ERS, Unizony S; Pan American League of Associations for Rheumatology. Pan American League of Associations for Rheumatology Guidelines for the treatment of ANCA-associated vasculitis. Lancet Rheumatol. 2023 PMID: 38251580

    Unizony S, Matza MA, Jarvie A, O'Dea D, Fernandes AD, Stone JH. Treatment for giant cell arteritis with 8 weeks of prednisone in combination with tocilizumab: a single-arm, open-label, proof-of-concept study. Lancet Rheumatol. 2023, PMID: 38251564

    Spiera RF, Unizony S, Warrington KJ, Sloane J, Giannelou A, Nivens MC, Akinlade B, Wong W, Bhore R, Lin Y, Buttgereit F, Devauchelle-Pensec V, Rubbert-Roth A, Yancopoulos GD, Marrache F, Patel N, Dasgupta B; SAPHYR Investigators. Sarilumab for Relapse of Polymyalgia Rheumatica during Glucocorticoid Taper. N Engl J Med. 2023, PMID: 37792612 Clinical Trial.

    Matza MA, Dagincourt N, Mohan SV, Pavlov A, Han J, Stone JH, Unizony S. Outcomes during and after long-term tocilizumab treatment in patients with giant cell arteritis. RMD Open. 2023, PMID: 37024237

    Scolnik M, Brance ML, Fern?ndez-?vila DG, Inoue Sato E, de Souza AWS, Magri SJ, Saldarriaga-Rivera LM, Ugarte-Gil MF, Flores-Suarez LF, Babini A, Zamora NV, Acosta Felquer ML, Vergara F, Carlevaris L, Scarafia S, Soriano Guppy ER, Unizony S; Pan American League of Associations for Rheumatology (PANLAR). Pan American League of Associations for Rheumatology guidelines for the treatment of giant cell arteritis. Lancet Rheumatol. 2022, PMID: 38261393

    Cid MC*, Unizony S*, Blockmans D, Brouwer E, Dagna L, Dasgupta B, Hellmich B, Molloy E, Salvarani C, Trapnell BC, Warrington KJ, Wicks I, Samant M, Zhou T, Pupim L, Paolini JF; KPL-301-C001 Investigators. Efficacy and safety of mavrilimumab in giant cell arteritis: a phase 2, randomised, double-blind, placebo-controlled trial. Ann Rheum Dis. 2022, PMID: 35264321. * Co-first authors

    Unizony S, Bao M, Han J, Luder Y, Pavlov A, Stone JH. Treatment failure in giant cell arteritis. Ann Rheum Dis. 2021, PMID: 34049857

    Stone JH, Tuckwell K, Dimonaco S, Klearman M, Aringer M, Blockmans D, Brouwer E, Cid MC, Dasgupta B, Rech J, Salvarani C, Schett G, Schulze-Koops H, Spiera R, Unizony S, Collinson N. Trial of Tocilizumab in Giant-Cell Arteritis. N Engl J Med. 2017, PMID: 28745999

Reviews: Comments and Ratings

4.8out of 5(139 Ratings, 53 Comments)

June 2025

It was my first time being seen by Dr. Unizony. I was referred to him by my Airway/Voice specialist at MGH, [redacted]. Dr. U. was prompt, pleasant, asked good questions and got right to the point of why I was there. He had reviewed my tests and gave me important feedback putting my mind to rest. [redacted] I was in good hands!


June 2025

Been seeing Dr Unizony for over 10 yrs with very complicated medical issues. He always stays current with my non rheum issues and thoughtfully incorporates the consequences and conflicts into our treatment plans. I feel well informed and involved in our decisions. Dr unizony is quite sharp and pleasant!


June 2025

Dr Unizony is one of the best I've ever dealt with. He is genuinely concerned with my situation and has worked very closely with my wife and me in attempting to diagnose and treat a very complicated set of illnesses. He works closely with us to make sure we understand the pluses and minuses of my new treatment plan.


June 2025

In addition to a thorough explanation and discussion of test results, symptoms, medications, and treatment plans for the giant cell arteritis for which he has been managing my excellent care for the past six years, Dr. Unizony took the time to inquire about my overall health and well-being, both physical and mental. That included quickly examining ... Read More


June 2025

I felt that the doctor was too brief for my visit. He never examined any part of my body. I explained that I needed a prescription re-fill. I started to tell him where I needed him to send the refill, but he abruptly ended my visit telling me to make another appointment in six months. It takes 2 hours driving each way - I felt that my appointment ... Read More


June 2025

Good listener Very professional


May 2025

Dr Unizony is wonderful, personable and remembers me. [redacted] Also, my rating of him goes back to when he identified through research what turned out to be, for me, a cure for my temporal arteritis that got me off steroids. Now I see him just for arthritis and I think this is not his specialty or interest. Still, he is helpful, and I like him.


May 2025

Dr Unizony is the best. He knows me, my history, remembers my issues. He is friendly and professional. I've been seeing him for 11 years, wouldn't see anyone else. Plus, a sense of humor!


April 2025

Dr. Unizony is tops in his field for the disease I have. We talked about clinical trials and I was able to get a ether understanding about my situation


April 2025

Excellent! Only concern, this was a consult for my regular rheumatologist. I do not see a write up or report for this visit. My Rheumatologist has not recieved any reoprt or write up. This info is needed.

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