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My laboratory studies the role of the TGF-beta/BMP signaling pathways in health and disease.
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Dr. Lin obtained his PhD from the Massachusetts Institute of Technology and Whitehead Institute in 1993. He also received his MD degree from Harvard Medical School in 1995 as part of the Harvard/MIT Division of Health Science and Technology program. He worked briefly as a post-doctoral research fellow at the Hubrecht Laboratory in the Netherlands. Dr. Lin then completed his medical Internship, Residency, and Clinical Fellowship in Nephrology at the Massachusetts General Hospital before joining the faculty of the Program in Membrane Biology and Nephrology Division in 1999. Now also a member of the MGH Center for Systems Biology, Dr. Lin has won numerous awards including the MGH Department of Medicine Stephen Krane Outstanding Young Investigator Award in 2008 and election to the American Society for Clinical Investigation in 2008. Dr. Lin is Board Certified in Internal Medicine and Nephrology by the American Board of Internal Medicine.
Dr. Lin's laboratory studies the role of the TGF-beta/BMP signaling pathways in health and disease. How TGF-beta/BMP ligands interact with receptors, and the role of the RGM/DRAGON family of novel BMP co-receptors in the regulation of iron metabolism are areas of active research. Ultimately, by studying this complex but important signaling system, he and his colleagues hope to shed light on diseases such as ischemic kidney disease, adult polycystic kidney disease, glomeruloscerosis, diabetic neuropathy, inflammatory bowel disease, hemochromatosis and anemia of chronic disease. His laboratory has recently published articles in prestigious journals including Nature Genetics, Nature Chemical Biology, Journal of Clinical Investigations, Blood, and the Journal of Biological Chemistry.
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