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Study Description

The goal of the trial is to study two types of radiation therapy: Intensity Modulated Radiation Therapy (IMRT) and Proton Beam Therapy (PBT). Both treatments are equally effective at killing prostate cancer cells, but each may cause side effects related to the radiation. Scientists have reason to believe that PBT may cause fewer serious side effects than IMRT, but so far research results have been mixed. This study is being done to find out which type of radiation is best for treating prostate cancer and whether there are significant differences in the side effects of each treatment. Our primary endpoint will use patient reports of side effects and general wellbeing two years after completing treatment. This means that your personal experiences will ultimately guide the study’s findings!

Participating Sites

Massachusetts General Hospital - Boston, MA
Status: Actively Enrolling 
Contact: Jason Efstathiou, MD, DPhil: jefstathiou@partners.org or 617-726-5866

University of Pennsylvania - Philadelphia, PA
Status: Actively Enrolling
Contact: Justin Bekelman, MD: bekelman@uphs.upenn.edu or 215-662-7266

Washington University - St. Louis, MO
Status: Actively Enrolling 
Contact: Jeffrey Michalski, MD, MBA: jmichalski@radonc.wustl.edu or 314-362-8566

Northwestern Medicine Chicago Proton Center - Warrenville, IL
Status: Actively Enrolling 
Contact: William Hartsell, MD: whartsell@chicagocancer.org or 630-821-6492

University of Washington - Seattle, WA
Status: Actively Enrolling 
Contact: Jing Zeng, MD: jzeng13@uw.edu or 206-598-4100 

Princeton Radiation Oncology - Somerset, NJ
Status: Actively Enrolling
Contact: Edward Soffen, MD: esoffen@prapa.com or 609-655-5755

Rutgers Cancer Institute of New Jersey - New Brunswick, NJ
Status: Actively Enrolling 
Contact: Rahul Parikh, MD: parikhrr@cinj.rutgers.edu or 732-253-3939

Provision Center for Proton Therapy - Knoxville, TN
Status: Actively Enrolling 
Contact: J. Ben Wilkinson, MD: ben.wilkinson@provisionproton.com or 865-862-1600

Mayo Clinic - Rochester, MN
Status: Actively Enrolling 
Contact: Thomas Pisansky, MD: pisansky.thomas@mayo.edu or 507-284-2511

Maryland Proton Treatment Center - Baltimore, MD
Status: Actively Enrolling 
Contact: Mark Mishra, MD: mmishra@umm.edu or 410-328-6080

University of Florida Health Proton Therapy Institute - Jacksonville, FL
Status: Actively Enrolling 
Contact: Nancy Mendenhall, MD: menden@shands.ufl.edu or 904-588-1475

University Hospitals - Cleveland, OH
Status: Actively Enrolling 
Contact: Rodney Ellis, MD: Rodney.Ellis@UHhospitals.org or 216-286-3903

ClinicalTrials.gov Listing

ClinicalTrials.gov Listing

Find additional information about PARTIQoL at our clinicaltrials.gov posting.

The Prostate Health Education Network

The Prostate Health Education Network

PHEN focuses on helping African American men fight prostate cancer.

Prostate Cancer Foundation

Prostate Cancer Foundation

PCF funds prostate cancer research around the world.

Zero – The End of Prostate Cancer

Zero – The End of Prostate Cancer

ZERO offers comprehensive support for prostate cancer patients and their families.