Research Spotlight: Comparing the GI Side Effects of Four Medications for Alcohol Use Disorder
Researchers found that injectable naltrexone had the fewest reported GI and liver-related side effects compared to the other drugs.
Alcohol-induced liver disease is caused by heavy use of alcohol. The liver's job is to break down alcohol. If you drink more than it can process, it can become badly damaged.
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Alcohol-induced liver disease is common. But it can be prevented. There are three types. Many heavy drinkers progress through these three types over time:
The liver is a large organ that sits up under the ribs on the right side of the belly (abdomen). The liver:
Alcohol-induced liver disease is caused by heavy use of alcohol. The liver's job is to break down alcohol. If you drink more than it can process, it can become badly damaged.
Fatty liver can happen in anyone who drinks a lot. Alcoholic hepatitis and alcoholic cirrhosis are linked to the long-term alcohol abuse seen in alcoholics.
Doctors don't know why some people who drink alcohol get liver disease while others do not. Research suggests there may be a genetic link, but this is not yet clear.
The effects of alcohol on the liver depend on how much and how long you have been drinking alcohol. These are the most common symptoms:
Fatty liver
Alcoholic hepatitis
Alcoholic cirrhosis, all of the symptoms of alcoholic hepatitis and the following:
The symptoms of alcohol-induced liver disease may look like other health problems. Always see a doctor for a diagnosis.
Your doctor will do a complete health history and physical exam. Other tests used to diagnose alcohol-induced liver disease may include:
The goal of treatment is to restore some or all normal functioning to the liver.
You must completely stop drinking alcohol. This may involve an alcohol treatment program. Sometimes you may also need to make changes to your diet. The liver is often able to fix some of the damage caused by alcohol so you can live a normal life. The scarring from cirrhosis is sometimes partially reversible. When liver tissue loss is severe enough to cause liver failure, most of the damage may be permanent. But the damage won't have any chance of reversing if you continue to drink alcohol. Different treatments are needed for different complications and symptoms of alcoholic liver disease. For example, you may need dietary changes, vitamins, salt limit, procedures to shrink swollen veins in the digestive tract, water pills (diuretics), medicines to treat confusion, and anti-inflammatory medicines.
In some cases, a liver transplant may be considered. But you must complete a rehab program and go through alcohol detox before this is even a choice.
Many people are embarrassed to tell their doctor about their alcohol intake. But there is help out there. So, it's important to discuss your alcohol intake truthfully with your doctor.
People with alcohol-induced liver disease are at increased risk of also having hepatitis C virus. Others have hepatitis B virus. Your doctor will test you for both and treat you if needed.
People with alcohol-induced liver disease are also at greater risk for liver cancer.
Those with cirrhosis often develop kidney problems, intestinal bleeding, fluid in the belly, confusion, liver cancer, and severe infections.
Tips to help you get the most from a visit to your doctor:
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