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Corrigan Minehan Heart Center
Cardiac resynchronization therapy involves the placement of an implantable biventricular pacing device with three leads (right atrial, right ventricular and left ventricular) that synchronize ventricular contractions.
Corrigan Minehan Heart Center
The Massachusetts General Hospital Cardiogenic Shock Team provides urgent evaluation and care to patients experiencing cardiogenic shock, a condition where the heart is unable to pump enough blood to support the needs of the body's organs.
Corrigan Minehan Heart Center
The Heart Failure and Cardiac Transplant Program at the Massachusetts General Hospital Corrigan Minehan Heart Center evaluates and manages a range of heart disease conditions that result in heart failure.
Department of Medicine
The Pulmonary Hypertension and Thromboendarterectomy Program at Massachusetts General Hospital is committed to the state-of-the-art evaluation, treatment and support of patients with all forms of pulmonary hypertension.
Corrigan Minehan Heart Center
Ventricular Assist Devices
Ventricular-assist devices aid the pumping ability of hearts in patients with advanced-stage heart failure.
What is heart failure?
The heart is a muscle that pumps oxygen-rich blood to all parts of the body. When you have heart failure, the heart can’t pump as well as it should. Or the heart muscle can’t relax and fill the pumping chamber with blood. Blood and fluid may back up into the lungs. This causes congestive heart failure. And it causes pulmonary edema. Some parts of the body also don’t get enough oxygen-rich blood. This means they can't work well. These problems lead to the symptoms of heart failure.
What causes heart failure?
Heart failure may result from:
Heart valve disease
High blood pressure
Active infections of the heart valves or heart muscle, such as endocarditis
A past heart attack
Coronary artery disease
Disease of the heart muscle (cardiomyopathy)
Heart disease or problems that are present at birth (congenital)
Heart rhythm problems (arrhythmias) that lead to ongoing fast heart rates
Long-term (chronic) lung disease and pulmonary embolism
A reaction to medicines such as those used for chemotherapy
Anemia and too much blood loss
Complications of diabetes
Obstructive sleep apnea
Alcohol and drug abuse
Certain viral infections
What are the symptoms of heart failure?
The most common symptoms of heart failure are:
Shortness of breath while resting, exercising, or lying flat
Weight gain from water retention
Visible swelling of the legs and ankles from fluid buildup. Sometimes the belly (abdomen) may swell.
Severe tiredness (fatigue) and weakness
Loss of appetite, nausea, and belly pain
Cough that doesn’t go away. It can cause blood-tinged or frothy sputum.
The severity of the condition and symptoms depends on how much of the heart's pumping ability has been affected. The first step in managing heart failure symptoms is knowing your baselines or what’s normal for you. How much do you weigh? Are you gaining weight but eating the same amount? How much can you do before you feel short of breath? Do your socks and shoes fit comfortably? Knowing what’s normal for you will help you see when symptoms are getting worse. Once you know your baselines, watch for changes daily.
The symptoms of heart failure may look like other health problems. Always see your healthcare provider for a diagnosis.
How is heart failure diagnosed?
Your healthcare provider will ask about your health history. He or she will give you a physical exam. You may need tests such as:
Chest X-ray. This test makes images of internal tissues, bones, and organs on film. This test shows the size and shape of your heart. Fluid in the lungs will also show up on X-ray.
Echocardiogram. This test is also called echo. It uses sound waves to assess the motion of the heart’s chambers and valves. The sound waves make an image on the screen as an ultrasound transducer is passed over the heart. This shows how well the heart pumps and relaxes. It also shows the thickness of the heart walls, and if the heart is enlarged. It is one of the most useful tests because it shows a lot of information about the heart’s function. And it helps guide treatment choices.
Electrocardiogram (ECG). This test records the electrical activity of the heart. It shows abnormal rhythms. It can sometimes find heart muscle damage.
BNP testing. B-type natriuretic peptide (BNP) is a hormone released from the ventricles that occurs with heart failure. BNP levels are useful in the quick assessment of heart failure. The higher the BNP levels, the worse the heart failure. BNP is measured from a blood sample.
Cardiac MRI. This test uses a magnetic field to make images of the heart and its nearby tissues. It can assess how the heart muscle and valves are working.
How is heart failure treated?
The cause of heart failure will guide the treatment plan. If heart failure is caused by a valve problem or coronary heart disease, then you may need a procedure. This may be a percutaneous coronary intervention. Or it may be surgery. If heart failure is caused by a problem such as anemia or an infection, you may need medicine to treat this problem.
Some causes of heart failure are reversible or short-term, such as in an acute infection. For many causes of heart failure there is no cure. But many forms of treatment can help with symptoms. They are listed below.
These healthy habits may help with heart failure:
Controlling blood pressure
Controlling blood sugar if you have diabetes
Losing weight, if needed
Limiting salt and fat in your diet
Not drinking alcohol or using illicit drugs
Getting enough rest
Other important lifestyle habits include getting vaccines such as for the flu and pneumococcal pneumonia.
If you have sleep problems, getting a sleep study get help find out what’s causing them. You may need to wear a C-PAP mask while you sleep. This will make sure you get enough oxygen. Too little oxygen can put stress on your heart.
Many types of medicines are available for heart failure. They include:
Angiotensin converting enzyme (ACE) inhibitors. These lower the pressure inside the blood vessels. This reduces the pressure that the heart has to pump against. They can also help the heart have better pumping ability over time.
Angiotensin receptor blockers (ARB). Some people get a cough and need to stop taking ACE inhibitors. If that happens, an ARB may work for you. These help relax blood vessels and reduce stress on the heart.
Angiotensin receptor-neprilysin inhibitors (ARNIs). This medicine combines an ARB and a neprilysin inhibitor. This can help the heart as noted above. And it can promote salt and water loss.
Sinus node I-f channel blocker. This may be used to lower your heart rate. Then then puts less stress on your heart.
Diuretics. These reduce the amount of fluid in the body. They are among the most important medicines in helping control fluid buildup in the body.
Vasodilators. These include hydralazine and nitroglycerin. These widen (dilate) the blood vessels. They reduce the workload on the heart.
Digitalis. This medicine helps the heart beat stronger. It may help with controlling heart rate if there is an abnormal heart rhythm.
Antiarrhythmics. These help keep normal heart rhythm.
Beta-blockers. These reduce the heart’s tendency to beat faster. They can also help the heart pump better over time.
Aldosterone blockers. This blocks the effects of the hormone aldosterone. This hormone causes sodium and water retention.
Statins or PCKS9 inhibitors. These lower the amount of bad cholesterol in your blood. They are not used to treat heart failure. But you may take one if you have high cholesterol. Or you may take one if you have had a past heart attack and are at risk for heart failure. People who have inherited forms of high cholesterol (familial hypercholesterolemia) may get help from PCKS9 inhibitors. These medicines lower cholesterol.
These include opening blocked arteries in the heart. This brings back blood flow to the heart muscle. It helps the ventricles squeeze as they should. The procedure can be done in the cardiac catheterization lab. It uses balloons to push plaque and blood clots out of the artery. It also uses stents to keep the artery open. This can also be done by bypassing blockages during surgery (coronary artery bypass surgery).
Heart valve repair or replacement
In some cases medicines can’t help heart failure caused by heart valves that are narrowed (stenosed) or leak (regurgitant). The heart valve can be repaired or replaced. This can be done as an open-heart procedure. Or it can be done by going through a small tube (catheter) that is put into an artery or vein.
If your heart failure has also damaged your heart’s electrical wiring system, a pacemaker can be implanted. This is done to restore normal heart rate and regularity. A cardiac resynchronizing pacemaker is used when 1 of the heart wires is damaged. This is often the wire located in the left ventricle. These pacemakers use implanted left and right sided wires to restore normal timing of the heart contraction in order to improve heart function.
ICD (implantable cardioverter defibrillator)
When heart muscle is damaged, dangerous heart circuits can form in the heart muscle. This leads to heart rhythms that can cause death. An ICD is implanted in the body to sense and treat these cardiac arrest rhythms. It does this by overdrive pacing the heart rhythm. Or it sends an energy shock to the heart.
VAD (ventricular assist devices)
This device is put in the chest during a surgery. It connects to an outside motor. The motor helps pump blood from the heart to the rest of the body. VADs can allow people with advanced heart failure to improve their overall symptoms and to walk more. This can be used as a long-term treatment. Or it can be used while someone waits for a donor heart for a transplant.
In some cases, the diseased heart must be replaced with a healthy one from a donor.
Talk with your healthcare providers about the risks, benefits, and possible side effects of all treatments.
What are possible complications of heart failure?
Complications of heart failure include:
Fluid buildup in the lungs (pulmonary edema)
Kidney and liver failure
Abnormal heart rhythms
Key points about heart failure
When you have heart failure, the heart can’t pump as well as it should.
Heart failure may result from health problems that affect the heart, such as high blood pressure, coronary artery disease, and heart attack.
Some common symptoms are shortness of breath, weight gain, and visible swelling of the legs and ankles.
A chest X-ray can help diagnose lung congestion.
Treatment varies based on the cause of heart failure. Most people are advised to make certain lifestyle changes and to take certain medicines, often for life. Procedures such as coronary intervention and surgery may be needed.
Tips to help you get the most from a visit to your healthcare provider:
Know the reason for your visit and what you want to happen.
Before your visit, write down questions you want answered.
Bring someone with you to help you ask questions and remember what your provider tells you.
At the visit, write down the name of a new diagnosis, and any new medicines, treatments, or tests. Also write down any new instructions your provider gives you.
Know why a new medicine or treatment is prescribed, and how it will help you. Also know what the side effects are.
Ask if your condition can be treated in other ways.
Know why a test or procedure is recommended and what the results could mean.
Know what to expect if you do not take the medicine or have the test or procedure.
If you have a follow-up appointment, write down the date, time, and purpose for that visit.
Know how you can contact your provider if you have questions.
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