Research Roundup
Research at the Mass General is interwoven throughout more than 30 departments, centers and units, and is conducted with the support and guidance of the Mass General Research Institute.
Contact Information
Boston, MAPhone: 617-726-1721
Waltham, MAPhone: 617-726-1721
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Mass General Pulmonary & Critical Care
55 Fruit St.
Boston, MA 02114
Phone: 617-726-1721
Mass General Brigham Healthcare Center
52 Second Ave.
Waltham, MA 02451
Phone: 617-726-1721
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The research in the Medoff Laboratory is dedicated to understanding the molecular basis of immune-mediated lung injury. Specifically we seek to delineate the mechanisms of lung inflammation as it relates to T cell-mediated lung disorders such as asthma, lung transplant rejection and respiratory viral infections. The laboratory utilizes cutting edge molecular biology techniques, genetic manipulation of mice, animal modeling of lung disease, integrative genomics, and translational studies in humans to understand these disease processes.
The laboratory is affiliated with the Pulmonary and Critical Care Unit in the Department of Medicine at MGH, as well as the Center for Immunology and Inflammatory Diseases, and the Division of Rheumatology, Allergy, and Immunology. We have collaborations with MGH laboratories in the Gastroenterology Unit, the Diabetes Unit, the Center for Computational and Integrative Biology, the Department of Molecular Biology, and the Department of Anesthesia, Critical Care, and Pain Medicine.
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Mass General is recognized as a top hospital on the U.S. News Best Hospitals Honor Roll for 2025-2026.
Research at the Mass General is interwoven throughout more than 30 departments, centers and units, and is conducted with the support and guidance of the Mass General Research Institute.
The third lecture in Massachusetts General Hospital’s Medical Grand Rounds’ COVID-19 series focused on the clinical care of acute respiratory failure and the potential for new therapies and treatment strategies.
Bolstered by the support of more than $30 million, researchers at the MGH are now teaming up with colleagues at Brigham and Women’s Hospital and the German pharmaceutical company Bayer AG to study new drug options for chronic lung diseases.

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